Osteoconduction of porous Ti metal enhanced by acid and heat treatments

Bone ingrowth into porous Ti metal is important for stable fixation of Ti metal implants to surrounding bone. However, without surface treatment this is limited to only a thin region of the outer surface of the Ti metal. In the present study, a porous Ti metal with a porosity of ~60 % and interpore connections of 70–200 micrometers in diameter was investigated in terms of its chemical and heat treatments, by implanting it into rabbit femur for periods varying from 3 to 12 weeks. The porous Ti metal subjected to heat treatment at 600 °C after H₂SO₄/HCl mixed acid treatment showed the largest bone ingrowth in comparison with those subjected to no treatment, only acid treatment, and only heat treatment even at an early stage after implantation, and remained as such even 12 weeks after implantation. Their bone ingrowths were well interpreted in terms of apatite-forming abilities of the Ti metals in body environment. Their apatite-forming abilities did not depend upon their surface roughness nor type of crystalline phase, but upon the positive surface charge.     

Barkhausen Noise Measurement System Using a Three-Pole Probe

In the present study, a three-pole probe is proposed for measurement of Barkhausen noise (BN). A system was constructed for forming a magnetic field using the three-pole probe and succeeded in forming rotating magnetic fields of the same amplitude in all directions and arbitrary orientated stationary alternating magnetic fields. Furthermore, a BN measurement system was constructed and used to measure the BN of a grain-oriented electrical steel sheet. The results show that the BN exhibits a large output in the direction of the easy magnetization axis of the specimen, and it is demonstrated that the BN measurement result using the rotating magnetic field formed by the three-pole probe is reliable.     

A Fourier-based algorithm for modelling aberrations in HETE-2''s imaging system

The High-Energy Transient Explorer, launched in October 2000, is a satellite experiment dedicated to the study of γ-ray bursts in a very wide energy range from soft X-ray to γ-ray wavelengths. The intermediate X-ray range (2–30 keV) is covered by the Wide-field X-ray Monitor (WXM), a coded aperture imager. In this article, an algorithm for reconstructing the positions of γ-ray bursts is described, which is capable of correcting systematic aberrations to approximately 1′ throughout the field of view. Functionality and performance of this algorithm have been validated using data from Monte-Carlo simulations as well as from astrometric observations of the X-ray source Scorpius X-1.     

Microlens arrays for integral imaging system

When designing a system capable of capturing and displaying 3D moving images in real time by the integral imaging (II) method, one challenge is to eliminate pseudoscopic images. To overcome this problem, we propose a simple system with an array of three convex lenses. First, the lateral magnification of the elemental optics and the expansion of an elemental image is described by geometrical optics, confirming that the elemental optics satisfies the conditions under which pseudoscopic images can be avoided. In using the II method, adjacent elemental images must not overlap, a condition also satisfied by the proposed optical system. Next, an experiment carried out to acquire and display 3D images is described. The real-time system we have constructed comprises an elemental optics array with 54 H x 59 V elements, a CCD camera to capture a group of elemental images created by the lens array, and a liquid crystal panel to display these images. The results of the experiment confirm that the system produces orthoscopic images in real time, and thus is effective for real-time application of the II method.     

Static characteristics and efficient control of compression- and absorption-type hybrid air conditioning system

A gas engine driven hybrid air conditioning system was constructed; it consisted of a gas engine, a single-stage compression-type refrigerator, and a single-effect absorption-type refrigerator that can be driven by shaft power and waste heat, respectively, from the gas engine. Its efficiency is greatly enhanced as compared to a conventional gas engine heat pump because it utilizes waste heat from the gas engine. This study used simulation and experiments to elucidate the static characteristics of this air conditioning system and develop a control system to drive this combined system efficiently. In the simulation results, the system COP at the design point was about 1.87 and, at 50% partial load operation, the performance increased by 14% because of the simultaneous manipulation of the input gas flow rate and hot water flow rate. The validity of the simulation was confirmed by experiments carried out using the actual constructed machine.     

Development of a novel calcium phosphate cement composed mainly of calcium sodium phosphate with high osteoconductivity

Two novel calcium phosphate cements (CPC) have been developed using calcium sodium phosphate (CSP) as the main ingredient. The first of these cements, labeled CAC, contained CSP, α-tricalcium phosphate (TCP), and anhydrous citric acid, whereas the second, labeled CABC, contained CSP, α-TCP, β-TCP, and anhydrous citric acid. Biopex^®-R (PENTAX, Tokyo, Japan), which is a commercially available CPC (Com-CPC), and OSferion^® (Olympus Terumo Biomaterials Corp., Tokyo, Japan), which is a commercially available porous β-TCP, were used as reference controls for analysis. In vitro analysis showed that CABC set in 5.7 ± 0.3 min at 22 °C and had a compressive strength of 86.0 ± 9.7 MPa after 5 days. Furthermore, this material had a compressive strength of 26.7 ± 3.7 MPa after 2 h in physiologic saline. CAC showed a statistically significantly lower compressive strength in the presence of physiologic saline and statistically significantly longer setting times than those of CABC. CABC and CAC exhibited apatite-forming abilities in simulated body fluid that were faster than that of Com-CPC. Samples of the materials were implanted into the femoral condyles of rabbits for in vivo analysis, and subsequent histological examinations revealed that CABC exhibited superior osteoconductivity and equivalent bioresorbability compared with Com-CPC, as well as superior osteoconductivity and bioresorbability compared with CAC. CABC could therefore be used as an alternative bone substitute material.     

Observation of resonant tunnelling via first excited level in double-barrier diodes

Two clear resonance peaks for each bias direction accompanying negative differential resistance are observed in the Al0.3Ga0.7/GaAs/Al0.3Ga0.7As double-barrier diode of 24 to 26 monolayer well thickness. These two peaks are found to be the resonant tunnelling through the ground and first excited energy levels in the well.     

Immobilization of lysozyme on the layered silicate RUB-15

Adsorption of lysozyme over layered silicate, denoted as RUB-15, and the modified compound RUB-15-nano have been studied. The amount of enzyme adsorbed onto RUB-15 or RUB-15-nano was smaller than that recently reported as being adsorbed onto mesoporous silicas such as MCM-41 or SBA-15. However, lysozyme adsorbed onto RUB-15-nano exhibits enzymatic activity. Lysozyme was found to be immobilized on RUB-15-nano, which was modified from the layered silicate RUB-15. RUB-15-nano may therefore be useful as an inorganic substrate to immobilize enzymes.     

Experimental and numerical investigation of ion temperature in an ECR plasma

The ion temperature in a large diameter plasma is measured with the high-resolution optical emission spectroscopy. It is found that the ion temperature is low when the radial distribution of the plasma is flat profile compared with that in the case of peaked profile. The results of numerical calculation carried out by using the hybrid model validate the assumption of Boltzmann distribution in plasma and agree well with the experimental results. Thus, it is concluded that the decrease of the ion temperature is caused by the decrease of the radial electric field.     

The effect of pressure during sintering on the strength and the fracture toughness of hydroxyapatite ceramics

Hydroxyapatite (HA) is known to be biocompatible and osteoconductive, and can be synthesized chemically. The objective of the present study is to clarify the effect of pressure during sintering on the mechanical properties of HA. HA was sintered using a hot press system at a uniaxial pressure ranging from 7.81 to 62.5 MPa at a maximum temperature of 1200^∘C with a heating rate of 10^∘C/min. The density of the HA increased with increasing pressure and peaked at the sintering pressure of 31.2 MPa. Four-points bending tests and fracture toughness measurements with indentation method were conducted to clarify the effect of sintering pressure. Bending strength decreased at the pressure > 31.2 MPa. This result indicates that residual stress generated during sintering process became larger with increasing pressure. Fracture toughness were also lower with high density HA.