全文获取类型
收费全文 | 273篇 |
免费 | 13篇 |
专业分类
电工技术 | 3篇 |
化学工业 | 68篇 |
金属工艺 | 6篇 |
机械仪表 | 4篇 |
建筑科学 | 11篇 |
矿业工程 | 1篇 |
能源动力 | 6篇 |
轻工业 | 15篇 |
水利工程 | 4篇 |
石油天然气 | 1篇 |
无线电 | 27篇 |
一般工业技术 | 68篇 |
冶金工业 | 36篇 |
自动化技术 | 36篇 |
出版年
2023年 | 5篇 |
2022年 | 8篇 |
2021年 | 8篇 |
2020年 | 10篇 |
2019年 | 12篇 |
2018年 | 12篇 |
2017年 | 15篇 |
2016年 | 6篇 |
2015年 | 4篇 |
2014年 | 14篇 |
2013年 | 11篇 |
2012年 | 14篇 |
2011年 | 14篇 |
2010年 | 9篇 |
2009年 | 9篇 |
2008年 | 7篇 |
2007年 | 6篇 |
2006年 | 6篇 |
2005年 | 8篇 |
2004年 | 7篇 |
2003年 | 5篇 |
2002年 | 6篇 |
2001年 | 3篇 |
2000年 | 4篇 |
1999年 | 7篇 |
1998年 | 10篇 |
1997年 | 9篇 |
1996年 | 2篇 |
1995年 | 5篇 |
1994年 | 4篇 |
1993年 | 4篇 |
1992年 | 3篇 |
1991年 | 3篇 |
1990年 | 6篇 |
1989年 | 2篇 |
1988年 | 3篇 |
1987年 | 3篇 |
1986年 | 2篇 |
1985年 | 2篇 |
1984年 | 2篇 |
1983年 | 2篇 |
1982年 | 1篇 |
1981年 | 4篇 |
1980年 | 1篇 |
1978年 | 2篇 |
1977年 | 1篇 |
1976年 | 3篇 |
1975年 | 2篇 |
排序方式: 共有286条查询结果,搜索用时 0 毫秒
71.
72.
Guruprasad Kunchur; Reddy B.V.Bhasker; Pandit Madhusudan W. 《Protein engineering, design & selection : PEDS》1990,4(2):155-161
Statistical analysis of 12 unstable and 32 stable proteins revealedthat there are certain dipeptides, the occurrence of which issignificantly different in the unstable proteins compared withthose in the stable ones. Based on the impact of these dipeptideson the unstable proteins over the stable ones, a weight valueof instability is assigned to each of the dipeptides. For agiven protein the summation of these weight values normalizedto the length of its sequence helps to distinguish between unstableand stable proteins. Results suggest that the in vivo instabilityof proteins is possibly determined by the order of certain aminoacids in its sequence. An attempt is made to correlate metabolicstability of proteins with features of their primary sequencewhere weight values of instability for a protein of known sequencecould thus be used as an index for predicting its stabilitycharacteristics. 相似文献
73.
The real area of contact between a rough and an ideally flat surface is evaluated from the spectral moments of the profile of the rough surface. A stochastic criterion for plastic deformation of the asperities is developed and applied to determine the percentage of plastic and elastic deformation in the total area of contact at a given separation. An illustration is given to delineate the theory through experimental profile data obtained from a ground surface. 相似文献
74.
Gopal Pandit Nabarupa Chowdhury Sk. Abdul Mohid Anil P. Bidkar Anirban Bhunia Sunanda Chatterjee 《ChemMedChem》2021,16(2):355-367
Herein we report the efficacy and toxicity of three de novo designed cationic antimicrobial peptides (AMPs) LL-14, VV-14 and ββ-14, where side chains of the hydrophobic amino acids were reduced gradually. The AMPs showed broad-spectrum antimicrobial activity against three pathogens from the ESKAPE group and two fungal strains. This study showed that side chains which are either too long or too short increase toxicity and lower antimicrobial activity, respectively. VV-14 was found to be non-cytotoxic and highly potent under physiological salt concentrations against several pathogens, especially Salmonella typhi TY2. These AMPs acted via membrane deformation, depolarization, and lysis. The activity of the AMPs is related to their ability to take on amphipathic helical conformations in the presence of microbial membrane mimics. Among AMPs with the same charge, hydrophobic interactions between the side chains of the residues with cell membrane lipids determine their antimicrobial potency and cytotoxicity. Strikingly, an optimum hydrophobic interaction is the crux of generating highly potent non-cytotoxic AMPs. 相似文献
75.
76.
Haresh T. More Aniruddha B. Pandit 《European Journal of Lipid Science and Technology》2010,112(4):428-433
Ethanol‐soluble (ES) lecithin mainly contains phosphatidylcholine (PC). The incorporation of caprylic acid into PC using immobilized phospholipase A2 (PLA2) and lipase was investigated. The Rhizomucor meihei lipase and the porcine pancreatic PLA2 were immobilized on the hydrophobic resin Diaion HP‐20 and the modification was carried out in hexane as solvent. HPTLC with densitometer technique was successfully used for monitoring the production of structured phospholipids (PL) (ML‐type PC, MM‐type PC, and lysophosphatidylcholine; L: long‐chain fatty acid, M: medium‐chain fatty acid). The various parameters such as the effects of reaction temperature, enzyme loading, and the effect of molar proportion of substrate were studied in order to determine the optimum reaction conditions for the acidolysis reaction. The optimal operating conditions for the PLA2‐catalyzed reaction were obtained as 50°C temperature, 50% (wt/wt of substrate) enzyme loading, and a 1:12 molar proportion of PC/caprylic acid. For the lipase‐catalyzed reaction, the optimized temperature was the same as for PLA2, but the enzyme loading and molar proportion were slightly lower, i.e., 40 % w/w of substrate and 1:9 PC/caprylic acid, respectively. The effects of these parameters on the production of structured PL were compared. Under these optimal conditions, the ML‐type PC content was higher in the PLA2‐catalyzed reaction, i.e., 45.29 mol%, and in the lipase‐catalyzed reaction it was 38.74 mol%. 相似文献
77.
P. K. Mishra A. K. Pradhan M. K. Pandit 《Journal of Adhesion Science and Technology》2016,30(7):708-728
Initiation and propagation of inter-laminar delamination in adhesive bonded spar wingskin joint (SWJ) made with laminated fibre-reinforced plastic (FRP) composite curved panels have been studied employing three-dimensional finite element analyses. In-plane and out-of-plane normal and shear stress distributions are seen to be highly three-dimensional in nature. Tsai-Wu coupled stress failure criteria have been employed to identify critical locations of onset of delamination-induced damage. This occurs underneath the toe-end of the spar overlap and at the inter-laminar surface between the first and second plies of the curved FRP wingskin panel. Significant edge effects on the joint strength have been observed due to the curvature geometry of the composite wingskin panels. Non-linear finite element analyses have been carried out for study of delamination propagation using contact and multi point constraint (MPC) elements. The use of contact elements prevents inter-penetration of delaminated surfaces. Whereas, sequential release of MPC elements facilitates computation of opening, sliding and cross-sliding modes of delamination-induced strain energy release rates (SERR) by using virtual crack closure technique. Variation in delamination lengths significantly effects the variation of peel and inter-laminar shear stresses and different modes of SERRs. Variations on the two delamination fronts are seen to be quite different indicating dis-similar propagation rates. The Mode I SERR (GI) predominantly governs the delamination propagation in the SWJ. 相似文献
78.
P Vaideeswar MJ Pandit JR Deshpande A Sivaraman IM Vora 《Canadian Metallurgical Quarterly》1993,39(3):159-161
Non-bacterial thrombotic endocarditis was found at autopsy in a 17 year old male patient of fibrolamellar type of hepatocellular carcinoma with pericardial metastases. This had resulted in multiple embolic cerebral infarcts with long standing hemiplegia and later death due to acute left ventricular failure. 相似文献
79.
80.
E. C. Pegg B. J. L. Kendrick H. G. Pandit H. S. Gill D. W. Murray 《Journal of the Royal Society Interface》2014,11(96)
The assessment of radiolucency around an implant is qualitative, poorly defined and has low agreement between clinicians. Accurate and repeatable assessment of radiolucency is essential to prevent misdiagnosis, minimize cases of unnecessary revision, and to correctly monitor and treat patients at risk of loosening and implant failure. The purpose of this study was to examine whether a semi-automated imaging algorithm could improve repeatability and enable quantitative assessment of radiolucency. Six surgeons assessed 38 radiographs of knees after unicompartmental knee arthroplasty for radiolucency, and results were compared with assessments made by the semi-automated program. Large variation was found between the surgeon results, with total agreement in only 9.4% of zones and a kappa value of 0.602; whereas the automated program had total agreement in 81.6% of zones and a kappa value of 0.802. The software had a ‘fair to excellent’ prediction of the presence or the absence of radiolucency, where the area under the curve of the receiver operating characteristic curves was 0.82 on average. The software predicted radiolucency equally well for cemented and cementless implants (p = 0.996). The identification of radiolucency using an automated method is feasible and these results indicate that it could aid the definition and quantification of radiolucency. 相似文献