Mauro Comes Franchini  Giovanni Baldi  Daniele Bonacchi  Denis Gentili  Guido Giudetti  Alessandro Lascialfari  Maurizio Corti  Patrick Marmorato  Jessica Ponti  Edoardo Micotti  Uliano Guerrini  Luigi Sironi  Paolo Gelosa  Costanza Ravagli  Alfredo Ricci 《Small (Weinheim an der Bergstrasse, Germany)》2010,6(3):366-370

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  总被引：1，自引：0，他引：1  

Paolo Ruffo  Livia Bazzana  Alberto Consonni  Anna Corradi  Andrea Saltelli  Stefano Tarantola   《Reliability Engineering & System Safety》2006,91(10-11):1155-1162

The evaluation of the exploration risk in the oil industry is a fundamental component of the decision process related to the exploratory phase. In this paper the two basic components of the exploratory risk: trap geometry and trapped hydrocarbon quantities (fluid), are compounded in a single coherent uncertainty and sensitivity approach. The results clarify that the model geometry influences each Petroleum System Modeling step and that the geometric uncertainty is correlated with the fluid uncertainty. The geometric uncertainty evaluation makes use of geostatistical techniques that produce a number of possible realizations of the trap geometry, all compatible with available data. The evaluation of the fluid uncertainty, through a Monte Carlo methodology, allows us to compute the possible quantities of oil and gas, generated in a basin and migrated from the hydrocarbon source location to each single trap. The final result is the probability distribution of oil and gas for each trap in the basin, together with other useful indicators like: the hydrocarbon filling probability map, the closure probability map, the drainage area probability map, the spilling paths probabilities, the trap-filling scenarios.  相似文献   

    

Xavier Joyeux  Paolo Mangiagalli  Jean Pinson 《Advanced materials (Deerfield Beach, Fla.)》2009,21(43):4404-4408

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Paolo Falcaro  Stefano Costacurta  Luca Malfatti  Masahide Takahashi  Tongjit Kidchob  Maria Francesca Casula  Massimo Piccinini  Augusto Marcelli  Benedetta Marmiroli  Heinz Amenitsch  Piero Schiavuta  Plinio Innocenzi 《Advanced materials (Deerfield Beach, Fla.)》2008,20(10):1864-1869

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M Morissette  TD Paolo 《Canadian Metallurgical Quarterly》1996,30(2):95-107

The effect of 17 beta-estradiol (E2) on the response of dopamine (DA) and serotonin (5-HT) to acute lithium in the brains of ovariectomized rats was investigated. An E2 injection (100 ng/s.c.) to ovariectomized rats did not change striatal DA levels, whereas the levels of its metabolites dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), increased 30 min later; concentrations of 5-HT and its metabolite, 5-hydroxyindoleacetic acid (5-HIAA), also remained unchanged. In the frontal cortex, DA, 5-HT, HVA and 5-HIAA levels remained unchanged after the E2 injection, whereas DOPAC levels and DOPAC/DA and HVA/DA ratios increased 30 min later. Injection of LiCl (10 mEq) decreased striatal DA levels, increased DOPAC levels and slightly decreased HVA levels; by contrast, frontal cortex DA and HVA levels increased but DOPAC levels were unchanged. A biphasic response of striatal 5-HT levels occurred, increasing shortly after injection of LiCl, followed by a decrease; 5-HIAA levels, however, increased. In the frontal cortex, injection of rats with LiCl led to a gradual increase in 5-HT levels, whereas 5-HIAA concentrations decreased. In the presence of E2, LiCl effected a greater decrease in striatal DA than injection of LiCl alone, advanced the DOPAC peak by 30 min and increased HVA levels; E2 had less effect on the 5-HT response to LiCl, except the decreases in 5-HT and 5-HIAA at 60 min were greater. Furthermore, in the striatum, the increased DA turnover caused by LiCl, estimated by the DOPAC/DA and HVA/DA ratios, was advanced in rats treated with E2. In the presence of E2, LiCl slightly increased frontal cortex DA, DOPAC and HVA levels compared with treatment with LiCl alone, whereas DOPAC levels decreased in rats treated with LiCl + E2 compared with levels in E2-treated rats. Generally, higher levels of 5-HT and 5-HIAA were measured in the frontal cortices of rats treated with LiCl + Ex compared with rats injected with LiCl. These results indicate that E2 potentiates the acute effect of lithium on striatal and frontal cortex DA and 5-HT levels and metabolism, suggesting a role of the hormonal state on this drug response.  相似文献   

    

Paolo Menesatti  Emiliano Canali  Giulio Sperandio  Gianluca Burchi  Ger Devlin  Corrado Costa 《Packaging Technology and Science》2012,25(4):203-215

Logistics is a fundamental component of the post‐harvest processes, especially in the floricultural sector where the products have to be marketed in short times after the cutting because of their fragility. In the previous years, new approaches to efficiently manage the logistical function and to reduce costs and environmental impacts have been consolidated. In this paper, the investments for two different containers for flower transportation, one disposable and one reusable, are compared, considering a specific supply chain located in central Italy. All data were provided by stakeholders. These were divided into four groups: purchasing, administration, logistical and disposal costs. For the reusable containers, a reverse logistical system, to collect the return components, was hypothesised by using the network analysis tool of the geographic information system (GIS). Results show that the use of a reusable system, which assures a production with less waste and less environmental pressures, is also economically advantageous. Reusable containers involve an initial investment but became cheaper from the second year of the investment and also remained convenient, considering all the costs related to the return collection of the items. Reusable system permits a financial advantage of approximately 140 k€ in total and 21 k€ for each year, considering all the nine years of analysis. Logistics is responsible of the great contribution of total cost in both the reusable and the disposable container (88% and 76%), probably because of the high fragmentation in the delivery service to sale points. Reverse logistics represents the 17% of the reusable container total costs. Copyright © 2011 John Wiley & Sons, Ltd.  相似文献   

    

Emanuele Treossi  Andrea Liscio  Xinliang Feng  Vincenzo Palermo  Klaus Müllen  Paolo Samorì 《Small (Weinheim an der Bergstrasse, Germany)》2009,5(1):112-119

Temperature‐enhanced solvent vapor annealing (TESVA) is used to self‐assemble functionalized polycyclic aromatic hydrocarbon molecules into ordered macroscopic layers and crystals on solid surfaces. A novel C₃ symmetric hexa‐peri‐hexabenzocoronene functionalized with alternating hydrophilic and hydrophobic side chains is used as a model system since its multivalent character can be expected to offer unique self‐assembly properties and behavior in different solvents. TESVA promotes the molecule's long‐range mobility, as proven by their diffusion on a Si/SiO_x surface on a scale of hundreds of micrometers. This leads to self‐assembly into large, ordered crystals featuring an edge‐on columnar type of arrangement, which differs from the morphologies obtained using conventional solution‐processing methods such as spin‐coating or drop‐casting. The temperature modulation in the TESVA makes it possible to achieve an additional control over the role of hydrodynamic forces in the self‐assembly at surfaces, leading to a macroscopic self‐healing within the adsorbed film notably improved as compared to conventional solvent vapor annealing. This surface re‐organization can be monitored in real time by optical and atomic force microscopy.  相似文献   

    

Jianing Chen  Pablo Albella  Zhaleh Pirzadeh  Pablo Alonso‐González  Florian Huth  Stefano Bonetti  Valentina Bonanni  Johan Åkerman  Josep Nogués  Paolo Vavassori  Alexandre Dmitriev  Javier Aizpurua  Rainer Hillenbrand 《Small (Weinheim an der Bergstrasse, Germany)》2011,7(16):2341-2347

The fundamental optical properties of pure nickel nanostructures are studied by far‐field extinction spectroscopy and optical near‐field microscopy, providing direct experimental evidence of the existence of particle plasmon resonances predicted by theory. Experimental and calculated near‐field maps allow for unambiguous identification of dipolar plasmon modes. By comparing calculated near‐field and far‐field spectra, dramatic shifts are found between the near‐field and far‐field plasmon resonances, which are much stronger than in gold nanoantennas. Based on a simple damped harmonic oscillator model to describe plasmonic resonances, it is possible to explain these shifts as due to plasmon damping.  相似文献   

    

Helena de Puig  Stefania Federici  Salmaan H. Baxamusa  Paolo Bergese  Kimberly Hamad‐Schifferli 《Small (Weinheim an der Bergstrasse, Germany)》2011,7(17):2477-2484

A study is presented of the nanomechanical phenomena experienced by nanoparticle‐conjugated biomolecules. A thermodynamic framework is developed to describe the binding of thrombin‐binding aptamer (TBA) to thrombin when the TBA is conjugated to nanorods. Binding results in nanorod aggregation (viz. directed self‐assembly), which is detectable by absorption spectroscopy. The analysis introduces the energy of aggregation, separating it into TBA–thrombin recognition and surface‐work contributions. Consequently, it is demonstrated that self‐assembly is driven by the interplay of surface work and thrombin‐TBA recognition. It is shown that the work at the surface is about ?10 kJ mol^?1 and results from the accumulation of in‐plane molecular forces of pN magnitude and with a lifetime of <1 s, which arises from TBA nanoscale rearrangements fuelled by thrombin‐directed nanorod aggregation. The obtained surface work can map aggregation regimes as a function of different nanoparticle surface conditions. Also, the thermodynamic treatment can be used to obtain quantitative information on surface effects impacting biomolecules on nanoparticle surfaces.  相似文献   

    

Artur Ciesielski  Artur R. Stefankiewicz  Felix Hanke  Mats Persson  Jean‐Marie Lehn  Paolo Samorì 《Small (Weinheim an der Bergstrasse, Germany)》2011,7(3):286-286

Hierarchical self‐assembly of small abiotic molecular modules interacting through noncovalent forces is increasingly being used to generate functional structures and materials for electronic, catalytic, and biomedical applications. The greatest control over the geometry in H‐bond supramolecular architectures, especially in H‐bonded supramolecular polymers, can be achieved by using conformationally rigid molecular modules undergoing self‐assembly through strong H‐bonds. Their binding strength depends on the multiplicity of the H‐bonds, the nature of donor/acceptor pairs and their secondary attractive/repulsive interactions. Here a functionalized molecular module is described, which is capable of self‐associating through self‐complementary H‐bonding patterns comprising four strong and two medium‐strength H‐bonds to form dimers. The self‐association of these phenylpyrimidine‐based dimers through directional H‐bonding between two lateral pyridin‐2(1H)‐one units of neighboring molecules allows the formation of highly compact 1D supramolecular polymers by self‐assembly on graphite. A concentration‐dependent study by scanning tunneling microscopy at the solid–liquid interface, corroborated by dispersion‐corrected density functional studies, reveals the controlled generation of either linear supramolecular 2D arrays, or long helical supramolecular polymers with a high shape persistence.  相似文献