Reaction Pathways in the Reduction of NO x Species by CO over Pt–Ba/Al2O3: Lean NO x Trap Catalytic Systems

The reduction by CO of NO _x species stored over Pt–Ba/Al₂O₃ Lean NO _x Trap systems is analysed in this work. The reaction mechanisms and pathways leading to N₂ formation both under dry and wet conditions are investigated by complementary transient dynamic experiments and FTIR analyses.     

Lipid,fatty acid,protein, amino acid and ash contents in four Brazilian red algae species

Four species of marine benthic algae (Laurencia filiformis, L. intricata, Gracilaria domingensis and G. birdiae) that belong to the phylum Rhodophyta were collected in Espírito Santo State, Brazil and investigated concerning their biochemical composition (fatty acid, total lipid, soluble proteins, amino acid and ash). The total content of lipid (% dry weight) ranged from 1.1% to 6.2%; fatty acid from 0.7% to 1.0%; soluble protein from 4.6% to 18.3%, amino acid from 6.7% to 11.3% and ash from 22.5% to 38.4%. Judging from their composition, the four species of algae appear to be potential sources of dietary proteins, amino acids, lipids and essential fatty acids for humans and animals.     

Influence of processing on the antioxidant capacity and bioactive compounds in jellies from different blackberry cultivars

The effect of thermal processing and the berry cultivar has been the subject of several studies, to serve as a basis for the least possible loss of bioactive compounds and antioxidant capacity. In Brazil, there are numerous blackberry cultivars under cultivation, and in this context, the aim of this work was to study how the bioactive compound contents and antioxidant capacity of blackberry jelly were influenced by the cultivars (Guarani, Brazos, Comanche, Tupy, Cherokee, Caingangue and Choctaw). Analysis was made of 7 fresh blackberry cultivars and 7 blackberry jelly formulations. Analysis of antioxidant activity, total phenolics, total anthocyanins and ascorbic acid was performed. It was verified that the contribution of the heat sensitive antioxidants compounds is considerable in all blackberry cultivars, and the degradation of these compounds was significantly different between the different blackberry cultivars. The Brazos and Caingangue cultivars stand out as undergoing the lowest losses in processing, resulting in jellies richer in bioactive compounds and higher antioxidant capacity.     

Assessing scientific collaboration through coauthorship and content sharing

Over the past decade there have been many investigations aimed at defining the role of scientists and research groups in their coauthorship networks. Starting from the assumptions of network analysis, in this work we propose an analytical definition of a collaboration potential between authors of scientific papers based on both coauthorships and content sharing. The collaboration potential can also be considered a useful tool to investigate the relationships between a single scientist and research groups, thus allowing for the identification of characteristic “types” of scientists (integrated, independent, etc.). We computed the collaboration potential for a set of authors belonging to research groups of an institute specialized in the field of Medical Genetics. The methods presented in the paper are rather general as they can be applied to compute a collaboration potential for a network of cooperating actors in every situation in which one can qualify the content of some activities and which of them are in common among the actors of the network.     

BROCCOLI: overlapping and outlier-robust biclustering through proximal stochastic gradient descent

Data Mining and Knowledge Discovery - Matrix tri-factorization subject to binary constraints is a versatile and powerful framework for the simultaneous clustering of observations and features, also...     

A 3D-CAM system for quick prototyping and microfabrication using excimer laser micromachining

A 3D CAM tool for rapid prototyping and small-scale production of MEMS devices based on excimer laser ablation process has been developed. The system’s algorithms use the 3D geometry of a microstructure, defined in a CAD model, and parameters that influence the process (etch rate, wall angle, stitching errors, etc.) to automatically generate a precise NC part program for the excimer laser machine.The performance of the system has been verified by NC part program generation for several 3D microstructures and subsequent machining trials. Stitching errors of 23.4±2.2 μm wide and 3.4±1.5 μm height were observed when overlap size between adjacent volumes were zero, when ablating 100×100 μm features in PC at fluence of 0.9 J/cm² using a workpiece dragging technique.When the size of the overlap was optimised by software based on optimal process parameters determined by Taguchi design of experiment method (DOE) and incorporated in the mask design the maximum stitching errors are reduced to 13.4±2.2 μm wide and 1.4±0.9 μm in height under the same conditions. Employing the hexagonal shaped mask with incorporated size of the image overlap, horizontal-stitching errors with width of 2.4±0.2 μm wide and 1.4±0.2 μm high were observed.The software simplifies part program creation and is useful for excimer laser operators who currently use a tedious trial and error process to generate microstructure parts.     

The Interplay between PARP Inhibitors and Immunotherapy in Ovarian Cancer: The Rationale behind a New Combination Therapy

Ovarian cancer (OC) has a high impact on morbidity and mortality in the female population. Survival is modest after platinum progression. Therefore, the search for new therapeutic strategies is of utmost importance. BRCA mutations and HR-deficiency occur in around 50% of OC, leading to increased response and survival after Poly (ADP-ribose) polymerase inhibitors (PARPis) administration. PARPis represent a breakthrough for OC therapy, with three different agents approved. On the contrary, immune checkpoint inhibitors (ICIs), another breakthrough therapy for many solid tumors, led to modest results in OC, without clinical approvals and even withdrawal of clinical trials. Therefore, combinations aiming to overcome resistance mechanisms have become of great interest. Recently, PARPis have been evidenced to modulate tumor microenvironment at the molecular and cellular level, potentially enhancing ICIs responsiveness. This represents the rationale for the combined administration of PARPis and ICIs. Our review ought to summarize the preclinical and translational features that support the contemporary administration of these two drug classes, the clinical trials conducted so far, and future directions with ongoing studies.     

Engineering Aspects of Selective Hydrocarbon Oxidation

This review represents an attempt to offer a comprehensive critical collection of information concerning chemical reaction engineering of selective hydrocarbon catalyric oxidation. Many excellent reviews are available in which the fundamental and industrialaspects of hetarogreous selective oxidation of hydrocarbons are presented and discussed[1-11]     

Approaching PM(2.5) and PM(2.5-10) source apportionment by mass balance analysis, principal component analysis and particle size distribution

A chemical characterization was carried out for PM(2.5) and PM(2.5-10) samples collected in a suburban area and the concentrations of 12 elements were determined in 8 size segregated fractions using a Berner Impactor. Two main objectives were proposed in this work: 1) to test for closure among chemical and gravimetric measurements of PM(2.5) and PM(2.5-10) and 2) evaluate the performance of Multilinear Regression Analysis (MLRA) and Mass Balance Analysis (MBA) in the determination of source contribution to Particulate Matter (PM) concentrations. The fraction unaccounted for by chemical analysis comprised on average 17% and 34% of gravimetric PM(2.5) and PM(2.5-10), respectively. The lack of closure in PM(2.5) and PM(2.5-10) mass (i.e., constituent concentrations not adding up to gravimetrically measured) could partly result from the presence of water associated with particles and errors in the estimation of unmeasured species. MLRA and MBA showed very similar results for the temporal variation of the source contributions. However, quantitatively important discrepancies could be observed, principally due to the lack of mass closure in PM(2.5) and PM(2.5-10). Both methods indicated that the major PM(2.5) aerosol mass contributors included secondary aerosol and vehicle exhaust. In the coarse fraction, marine and mineral aerosol contributions were predominant.     

Selective catalytic reduction (SCR) of NO by NH3 over TiO2-supported V2O5–WO3 and V2O5–MoO3 catalysts

A comparison between commercial and model WO₃–V₂O₅/TiO₂ and MoO₃–V₂O₅/TiO₂ SCR catalysts is considered in this study. The data indicate that WO₃ and MoO₃ behave as “structural” and “chemical” promoters for the catalysts. MoO₃-based catalysts are more active but less selective than WO₃–V₂O₅/TiO₂ catalysts in the SCR reaction, although in the presence of water the catalytic performances of the investigated samples are comparable. This revised version was published online in August 2006 with corrections to the Cover Date.