New fully-differential amplifier-less pipelined ADC with wide power scalability and ERBW

A 24 GHz power amplifier for direct-conversion transceiver using standard 0.18 μm CMOS technology is reported. The three-stage power amplifier comprises two cascaded cascode stages for high power gain, followed by a common-source stage for high power linearity. To increase the saturated output power (P_sat) and power-added efficiency (PAE), the output stage adopts a Wilkinson-power-divider- and combiner-based two-way power dividing and combining architecture. The power amplifier consumes 163.8 mW and achieves power gain (S₂₁) of 22.8 dB at 24 GHz. The corresponding 3-dB bandwidth of S₂₁ is 4.2 GHz, from 22.7 to 26.9 GHz. At 24 GHz, the power amplifier achieves P_sat of 15.9 dBm and maximum PAE of 14.6 %, an excellent result for a 24 GHz CMOS power amplifier. In addition, the measured output 1-dB compression point (OP_1dB) is 7 dBm at 24 GHz. These results demonstrate the proposed power amplifier architecture is very promising for 24 GHz short-range communication system applications.     

A single parameter to evaluate stress state in rail head for rolling contact fatigue analysis

Based on the Smith‐Watson‐Topper (SWT) method, a phenomenological approach for multiaxial fatigue analysis, the maximum SWT parameter is proposed as a single parameter to evaluate the stress state in the rail head for assessing the fatigue integrity of the structure. A numerical procedure to calculate the maximum SWT parameter from a finite element analysis is presented and applied in a case study, where the stress and strain fields due to wheel/rail rolling contact are obtained from a three‐dimensional finite element simulation with the steady‐state transport analysis technique. The capability of the SWT method to predict fatigue crack initiation in the rail head is confirmed in the case study. Analogous to von Mises stress for strength analysis, the maximum SWT parameter can be applied to evaluate the fatigue loading state not only in rail head due to rolling contact fatigue but also in a generic structure subjected to a cyclic loading.     

Conditions of applying Oliver–Pharr method to the nanoindentation of particles in composites

The indentation test is a popular experimental method to measure a material’s mechanical properties such as elastic modulus and hardness, and the Oliver–Pharr method is commonly used in commercial indentation instruments to obtain these two quantities. To apply the Oliver–Pharr method correctly in all of these cases, it is essential to know the limitations of this method. The present study focuses on the applicability of the Oliver–Pharr method to measure the mechanical properties of particles in composites. The finite element method is used to undertake virtual indentation tests on a particle embedded in a matrix. In our numerical studies, the indentation “pile-up” phenomenon is generally observed in our numerical case studies, which indicates that the contact area used for predicting the elastic modulus should be measured directly, not be estimated from the indentation curve. The Oliver–Pharr method based on the real contact area is applied to estimate the elastic modulus of the particles by using the indentation curve from the numerical simulation, with the estimated elastic modulus being compared with the input value. Applying the real contact area value (not the one predicted from the indentation curve) we show that the Oliver–Pharr method can still be applied to measure the elastic modulus of the particle with sufficient accuracy if the indentation depth is smaller than the particle-dominated depth, a value defined in this work. The influences of the matrix and particle properties on the particle-dominated depth are studied using a dimensional analysis and parametric study. Our results provide guidelines to allow the practical application of the Oliver–Pharr method to measure the elastic modulus of particles in composites. This could be particularly important where particles are formed in situ in a matrix (as opposed to being preformed and subsequently incorporated in a matrix), or when the modulus of individual performed particles is required such as for subsequent modelling, but the modulus of individual material particles (or its material) cannot readily be determined.     

Development of a Rapid Fluorescent Diagnostic System for Early Detection of the Highly Pathogenic Avian Influenza H5 Clade 2.3.4.4 Viruses in Chicken Stool

Rapid diagnosis is essential for the control and prevention of H5 highly pathogenic avian influenza viruses (HPAIVs). However, highly sensitive and rapid diagnostic systems have shown limited performance due to specific antibody scarcity. In this study, two novel specific monoclonal antibodies (mAbs) for clade 2.3.4.4 H5Nx viruses were developed by using an immunogen from a reversed genetic influenza virus (RGV). These mAbs were combined with fluorescence europium nanoparticles and an optimized lysis buffer, which were further used for developing a fluorescent immunochromatographic rapid strip test (FICT) for early detection of H5Nx influenza viruses on chicken stool samples. The result indicates that the limit of detection (LoD) of the developed FICT was 40 HAU/mL for detection of HPAIV H5 clade 2.3.4.4b in spiked chicken stool samples, which corresponded to 4.78 × 10⁴ RNA copies as obtained from real-time polymerase chain reaction (RT-PCR). An experimental challenge of chicken with H5N6 HPAIV is lethal for chicken three days post-infection (DPI). Interestingly, our FICT could detect H5N6 in stool samples at 2 DPI earlier, with 100% relative sensitivity in comparison with RT-PCR, and it showed 50% higher sensitivity than the traditional colloidal gold-based rapid diagnostic test using the same mAbs pair. In conclusion, our rapid diagnostic method can be utilized for the early detection of H5Nx 2.3.4.4 HPAIVs in avian fecal samples from poultry farms or for influenza surveillance in wild migratory birds.     

In-Situ X-ray Diffraction Analysis of Metastable Austenite Containing Steels Under Mechanical Loading at a Wide Strain Rate Range

Metallurgical and Materials Transactions A - This paper presents and discusses the methodology and technical aspects of mechanical tests carried out at a wide strain rate range with simultaneous...