2000年NIM铯冷原子喷泉时间频率基准装置研究的进展

本文报导了中国计量科学研究院(MM)研制新一代"激光冷却铯原子喷泉"国家时间频率基准装置的进展实现了从磁光阱(MOT)过渡到光学黏胶(OM)装载-冷却铯(Cs)原子,利用飞行时间(TOF)法记录到信噪比优于40的原子云荧光信号;原子经后冷却达到(10～20)μK;用光学黏胶从铯蒸气直接获得了冷原子云.并给出了对实验的讨论.     

不同1、2-含量聚丁二烯及其硅氢加成产物的制备与透气性能的研究

合成了不同1、2-含量聚丁二烯及其硅氢加成产物,对聚丁二烯不饱和主链双键及乙烯基(外双键)的硅氢加成反应活性研究表明乙烯基的硅氢加成活性远高于主链双键。含氢硅烷的极性、反应介质的碱性都有利于硅氢加成反应的进行。硅氢加成产物的抗张强度较加成前提高,伸长率下降。在1、2-含量达到40%左右时成膜后膜对氧气透过率(Po_2)最大,选择分离系数(α+(N_2)~(O_2))最低。聚丁二烯三烷基硅氢加成产物成膜后膜对氧气的透过率均有较大改善,选择分离系数变化不大。     

Architecture engineering of hierarchically porous chitosan/vacuum-stripped graphene scaffold as bioanode for high performance microbial fuel cell

The bioanode is the defining feature of microbial fuel cell (MFC) technology and often limits its performance. In the current work, we report the engineering of a novel hierarchically porous architecture as an efficient bioanode, consisting of biocompatible chitosan and vacuum-stripped graphene (CHI/VSG). With the hierarchical pores and unique VSG, an optimized bioanode delivered a remarkable maximum power density of 1530 mW m(-2) in a mediator-less MFC, 78 times higher than a carbon cloth anode.     

Hydrodynamic Instability Analysis of the Axial Flow Pump in an Ethylene Polymerization Loop Reactor

The hydrodynamic instability of the axial flow pump in a loop reactor has long been a troubling issue to be solved in the polyethylene industry due to the lack of a better mechanismic understanding.Generally,the instability of an axial flow pump can be reflected by the fluctuation of the pump head.In this study,the transient computational fluid dynamics(CFD)simulation is adopted to study the hydrodynamic instability of the axial flow pump used in an ethylene polymerization loop reactor.The resul...     

Secreted HSP90α-LRP1 Signaling Promotes Tumor Metastasis and Chemoresistance in Pancreatic Cancer

The extracellular heat shock protein 90α (eHSP90α) has been reported to promote cancer cell motility. However, whether pancreatic cancer (PC) cells expressed membrane-bound or secreted HSP90α, as well as its underlying mechanism for PC progression, were still unclear. Our study demonstrated that the amounts of secreted HSP90α proteins were discrepant in multiple PC cells. In addition, highly invasive Capan-2 cells have a higher level of secreted HSP90α compared with those of less invasive PL45 cells. The conditioned medium of Capan-2 cells or recombinant HSP90α treatment stimulated the migration and invasion of PC cells, which could be prevented with a neutralizing anti-HSP90α antibody. Furthermore, secreted HSP90α promoted elements of epithelial–mesenchymal transition in PL45 cells, including increases in vimentin and Snail expressions, decreases in E-cadherin expression, and changes in cell shape towards a mesenchymal phenotype, but these phenomena were reversed by the anti-HSP90α antibody in Capan-2 cells. In addition, high levels of low-density lipoprotein receptor-related protein 1 (LRP1) were associated with worsened patient survival in pancreatic adenocarcinoma. We demonstrated LRP1 as a receptor of eHSP90α for its stimulatory role in metastasis, by activating the AKT pathway. In addition, silencing LRP1 enhanced the chemosensitivity to gemcitabine and doxorubicin in Capan-2 cells. Therefore, our study indicated that blocking secreted HSP90α underlies an aspect of metastasis and chemoresistance in PC.     

Studied on a novel human keratinocyte membrane delivery system in vitro

The culture of keratinocytes on flexible membranes has been proposed as a means to simplify, accelerate and improve the efficiency with which proliferating cells are delivered to full thickness or non-healing skin defects. The purpose of this article was to study the ability of chitosan-gelatin manbranes to facilitate the growth of human keratinocytes. The membranes with different chitosan contents were studied. The surface properties of chitosan-gelatin membranes were investigate by SEM, and water contact angle test. The mechanical property of the membranes was tested. Data implied that gelatin could make the membranes more flexible and hydrophilic than chitosan membranes, which may regulate the seeded cells behavior. Loading human keratinocytes on chitosan-gelatin membranes, cells attachment, spread, and growth were investigated by light microscopy, SEM, and MTT test. The results suggested that the adhesion and proliferation of keratinocytes seeded on chitosan-gelatin membranes were same as on tissue culture plate, in which gelatin could modify the interaction between keratinocytes and chitosan membranes. Therefore, chitosan-gelatin membrane is a good candidate for keratinocytes delivery system.     

碳纤维增强碳化硅陶瓷基复合材料的研究

使用CVD技术提高纤维增强陶瓷基复合材料的密度是很困难的,因为它很难使反应气体完全渗入到基体里面.这是由于"瓶颈"效应所致,即CVD过程阻塞了基体表面的小气孔,进而封闭了通向大气孔的入口.为此,提出一种新的方法位控CVD(PCCVD),来克服上述困难.通过控制反应气体通道位置和试样的加热位置,从而达到控制沉积位置,使沉积界面始终处于开孔状态.使用PCCVD技术制造的C/SiC复合材料,实际密度可达其理论密度的96%.