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991.
Daeha Joung Vincent Truong Colin C. Neitzke Shuang‐Zhuang Guo Patrick J. Walsh Joseph R. Monat Fanben Meng Sung Hyun Park James R. Dutton Ann M. Parr Michael C. McAlpine 《Advanced functional materials》2018,28(39)
A bioengineered spinal cord is fabricated via extrusion‐based multimaterial 3D bioprinting, in which clusters of induced pluripotent stem cell (iPSC)‐derived spinal neuronal progenitor cells (sNPCs) and oligodendrocyte progenitor cells (OPCs) are placed in precise positions within 3D printed biocompatible scaffolds during assembly. The location of a cluster of cells, of a single type or multiple types, is controlled using a point‐dispensing printing method with a 200 µm center‐to‐center spacing within 150 µm wide channels. The bioprinted sNPCs differentiate and extend axons throughout microscale scaffold channels, and the activity of these neuronal networks is confirmed by physiological spontaneous calcium flux studies. Successful bioprinting of OPCs in combination with sNPCs demonstrates a multicellular neural tissue engineering approach, where the ability to direct the patterning and combination of transplanted neuronal and glial cells can be beneficial in rebuilding functional axonal connections across areas of central nervous system (CNS) tissue damage. This platform can be used to prepare novel biomimetic, hydrogel‐based scaffolds modeling complex CNS tissue architecture in vitro and harnessed to develop new clinical approaches to treat neurological diseases, including spinal cord injury. 相似文献
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Preparation and properties of pure crystalline perovskite CeFeO3 thin films with vanadium doping 总被引:1,自引:0,他引:1 下载免费PDF全文
Nanxi Lin Lina Huo Haipeng Liu Xiao Fang Shuting Wu Xin Chen Xiaolin Hu Naifeng Zhuang 《Journal of the American Ceramic Society》2017,100(7):2932-2938
Cerium ferrite (CeFeO3) thin films doped with vanadium (V:CeFeO3) were grown on SiO2 quartz glass and <100>‐oriented SrTiO3 (STO) crystal substrates by the radio‐frequency magnetron sputtering method in this study. The effects of crystallization, substrate, and V‐doping on the quality, the magnetic property and the magneto‐optical property of as‐prepared films are investigated. V:CeFeO3 film grown on STO substrate has better crystallinity and has better lattice integrity due to the higher lattice matching between substrate and film. The magnetic hysteresis loop and the magnetic circular dichroism spectra show that the magnetization strength and the magneto‐optical properties of V:CeFeO3 films have the significant anisotropy. Moreover, V‐doping and the stress lead to the change in easy magnetization direction of film. It shows that the perovskite B‐site doping with transition‐metal ion has significant influence on the magnetic and the magneto‐optical properties of CeFeO3 thin films. 相似文献
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Flow properties of polymer melt in longitudinal ultrasonic‐assisted microinjection molding 下载免费PDF全文
Microplastic parts are usually fabricated by microinjection molding (µIM) which is an effective and low cost method. But the defects, such as short shot, often appear during fabricating plastic parts with high aspect ratio structures or complex shapes. a longitudinal ultrasonic‐assisted microinjection molding (LUµIM) method effectively improve the molding quality. In the paper, the mechanism that the ultrasonic vibration impacts on the polymer melt is investigated. Considering from the point view of energy effect, mechanical energy transmission, and mechanical energy conversion, which are divided from the energy of ultrasonic vibration, are analyzed. The model of energy transmission and a new rheological equation including the parameters of ultrasonic vibration are established to describe the rheological behavior of polymer melt in microcavity. The simulation results show that the ultrasonic vibration improves the viscosity field and the velocity field in complex shaped microcavity, and leads to a better filling capability and uniformity of the polymer melt. This research achievement can be used to guide the process flow and parameter selection of LUµIM. POLYM. ENG. SCI., 57:797–805, 2017. © 2016 Society of Plastics Engineers 相似文献
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随着信息时代的到来,计算机和通信在信息的传输、收集、存储、处理和分发中扮演了极其重要的角色,故而,中小企业内部的网络建设已经成为提升中小企业核心竞争力的关键因素. 相似文献
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通过宏观拍照、傅立叶变换红外光谱(FTIR)、热重(TG)分析和扫描电子显微镜(SEM)等方法详细分析了福建省沿海某区域雷击烧蚀的部分失效样品,使用有限元分析方法分析了绝缘子负荷侧的受力情况。结果表明,失效样品主要表现出断链,氧化老化较少。炭黑量过多会使绝缘层过早失效。绝缘子负荷侧存在最大的应力和应力变形,使得设计上"先天不足"架空绝缘导线在电弧电流产生的堆积热量和应力作用下力学性能降低,产生大量裂纹。绝缘材料本身避免"绝缘薄弱处"是从根本上真正提高架空绝缘导线寿命的关键。 相似文献
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Novel Direct Nanopatterning Approach to Fabricate Periodically Nanostructured Perovskite for Optoelectronic Applications 下载免费PDF全文
Jian Mao Wei E. I. Sha Hong Zhang Xingang Ren Jiaqing Zhuang Vellaisamy A. L. Roy Kam Sing Wong Wallace C. H. Choy 《Advanced functional materials》2017,27(10)
While indirectly patterned organic–inorganic hybrid perovskite nanostructures have been extensively studied for use in perovskite optoelectronic devices, it is still challenging to directly pattern perovskite thin films because perovskite is very sensitive to polar solvents and high‐temperature environments. Here, a simple and low‐cost approach is proposed to directly pattern perovskite solid‐state films into periodic nanostructures. The approach is basically perovskite recrystallization through phase transformation with the presence of a periodic mold on an as‐prepared solid‐state perovskite film. Interestingly, this study simultaneously achieves not only periodically patterned perovskite nanostructures but also better crystallized perovskites and improved optical properties, as compared to its thin film counterpart. The improved optical properties can be attributed to the light extraction and increased spontaneous emission rate of perovskite gratings. By fabricating light‐emitting diodes using the periodic perovskite nanostructure as the emission layers, approximately twofold higher radiance and lower threshold than the reference planar devices are achieved. This work opens up a new and simple way to fabricate highly crystalline and large‐area perovskite periodic nanostructures for low‐cost production of high‐performance optoelectronic devices. 相似文献