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赤道几内亚吉部洛水电站厂房为半地下式厂房,原设计方案考虑在机组间设永久变形缝,但由于该厂房上游地下水位很高,厂房底部水头超过30 m,所以在上游边墙和楼板的分缝处会出现局部应力和变形过大。为减小应力和变形,另考虑后浇带方案,以增强其整体性。此方案下厂房成为一个整体结构,不存在变形缝,但同时也形成了超过50 m的大跨度混凝土高边墙和楼板结构,超出了厂房设计规范中允许的最大跨度,有必要对其进行论证。采用地震反应谱法并考虑动静叠加,对两方案在设计地震作用下的地震响应作了对比分析。结果表明:后浇带方案不仅能减小厂房局部应力和变形,还能使厂房满足抗震要求,优于原设缝方案。为类似存在高水头压力问题的水电站厂房设计提供可靠参考和借鉴。 相似文献
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WinPE在启动时会读取TXTSETLTP.SIF内容,用文本安装模式加载第三方驱动.利用这一功能我们可以把驱动封装到WinPE启动系统中. 相似文献
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从一般的网络攻击技术出发,分析现有网络安全技术的弱点,采用主动防御的新思想来应对当前反病毒技术远远落后病毒技术发展的局面。重点对基于动态陷阱生成技术的蠕虫病毒特征码的自动提取进行研究,对收集的新型蠕虫病毒特征扩充IDS的特征库,弥补入侵检测系统对未知病毒攻击无法识别问题,完善防御系统。 相似文献
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Wei Shang Guohao Jing Yulin Wang Tianlong Chen Zhou Liu Zhongzhong Zheng 《Asian journal of control》2023,25(4):2699-2719
The formation control for multiple quadrotors subject to maintaining the formation configuration and collision avoidance in the situation of stochastic links failure is investigated in this paper. First, the distributed formation controller is designed, the position controller is developed to manage the desired formation of position, and the attitude controller is developed to control the translation and rotation movements of the quadrotor. Then, in order to avoid the collisions between multiple quadrotors and the obstacles, a potential energy function method is introduced into the quadrotor formation control combined with the nest adaptive control. Inspired by the design of event trigger controller, a communication compensation controller is designed to ensure the stability of quadrotor formation under the condition of random communication interruption and recovery. Moreover, a prescribed time function is designed, which means the convergence time of the formation system can be set in advance. The prescribed time stability of the formation control system is proved by Lyapunov theory. Finally, the simulation results verify the effectiveness and superiority of this method. 相似文献
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Chung Yen Ang Si Yu Tan Cathleen Teh Jia Min Lee Mun Fei Eddy Wong Qiuyu Qu Li Qing Poh Menghuan Li Yuanyuan Zhang Vladimir Korzh Yanli Zhao 《Small (Weinheim an der Bergstrasse, Germany)》2017,13(7)
Responsive nanomaterials have emerged as promising candidates as drug delivery vehicles in order to address biomedical diseases such as cancer. In this work, polymer‐based responsive nanoparticles prepared by a supramolecular approach are loaded with doxorubicin (DOX) for the cancer therapy. The nanoparticles contain disulfide bonds within the polymer network, allowing the release of the DOX payload in a reducing environment within the endoplasm of cancer cells. In addition, the loaded drug can also be released under acidic environment. In vitro anticancer studies using redox and pH dual responsive nanoparticles show excellent performance in inducing cell death and apoptosis. Zebrafish larvae treated with DOX‐loaded nanoparticles exhibit an improved viability as compared with the cases treated with free DOX by the end of a 3 d treatment. Confocal imaging is utilized to provide the daily assessment of tumor size on zebrafish larva models treated with DOX‐loaded nanoparticles, presenting sustainable reduction of tumor. This work demonstrates the development of functional nanoparticles with dual responsive properties for both in vitro and in vivo drug delivery in the cancer therapy. 相似文献
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Xinlong Fan Jin Liu Xiangkun Jia Yin Liu Hao Zhang Shenqiang Wang Baoliang Zhang Hepeng Zhang Qiuyu Zhang 《Nano Research》2017,10(9):2905-2922
A facile one-step approach to synthesize various phase-separated porous, raspberry-like, flower-like, core–shell and anomalous nanoparticles and nanocapsules via 1,1-diphenylethene (DPE) controlled soap-free emulsion copolymerization of styrene (S) with glycidyl methacrylate (GMA), or acrylic acid (AA) is reported. By regulating the mass ratio of S/GMA, transparent polymer solution, porous and anomalous P(S-GMA) particles could be produced. The P(S-GMA) particles turn from flower-like to raspberry-like and then to anomalous structures with smooth surface as the increase of divinylbenzene (DVB) crosslinker. Transparent polymer solution, nanocapsules and core–shell P(S-AA) particles could be obtained by altering the mole ratio of S/AA; anomalous and raspberry-like P(S-AA) particles are produced by adding DVB. The unpolymerized S resulted from the low monomer conversion in the presence of DPE aggregates to form nano-sized droplets, and migrates towards the external surfaces of the GMA-enriched P(S-GMA) particles and the internal bulk of the AA-enriched P(S-AA) particles. The nano-sized droplets function as in situ porogen, porous P(S-GMA) particles and P(S-AA) nanocapsules are produced when the porogen is removed. This novel, facile, one-step method with excellent controllability and reproducibility will inspire new strategies for creating hierarchical phase-separated polymeric particles with various structures by simply altering the species and ratio of comonomers. The drug loading and release experiments on the porous particles and nanocapsules demonstrate that the release of doxorubicin hydrochloride is very slow in weakly basic environment and quick in weakly acidic environment, which enables the porous particles and nanocapsules with promising potential in drug delivery applications. 相似文献
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Phototherapy: Metal–Organic‐Framework‐Derived Mesoporous Carbon Nanospheres Containing Porphyrin‐Like Metal Centers for Conformal Phototherapy (Adv. Mater. 38/2016) 下载免费PDF全文
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