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排序方式: 共有2910条查询结果,搜索用时 11 毫秒
61.
Rafael K. de Andrades Márcio Dorn Daniel S. Farenzena Luis C. Lamb 《Expert systems with applications》2013,40(13):5210-5218
The Medical and Pharmaceutical industries have shown high interest in the precise engineering of protein hormones and enzymes that perform existing functions under a wide range of conditions. Proteins are responsible for the execution of different functions in the cell: catalysis in chemical reactions, transport and storage, regulation and recognition control. Computational Protein Design (CPD) investigates the relationship between 3-D structures of proteins and amino acid sequences and looks for all sequences that will fold into such 3-D structure. Many computational methods and algorithms have been proposed over the last years, but the problem still remains a challenge for Mathematicians, Computer Scientists, Bioinformaticians and Structural Biologists. In this article we present a new method for the protein design problem. Clustering techniques and a Dead-End-Elimination algorithm are combined with a SAT problem representation of the CPD problem in order to design the amino acid sequences. The obtained results illustrate the accuracy of the proposed method, suggesting that integrated Artificial Intelligence techniques are useful tools to solve such an intricate problem. 相似文献
62.
Rafael Asorey-Cacheda Belén Pedrero-López Francisco J. González-Castaño 《Multimedia Tools and Applications》2013,64(3):627-647
Implicit Error Correction is a near Video-on-Demand (nVoD) schema that trades bandwidth utilization for initial playback delay while potentially allowing an infinite number of users. Additionally, it provides error protection without further bandwidth increase by exploiting the implicit redundancy of nVoD protocols, using linear combinations of the segments transmitted in a given time slot. This paper introduces a new implementation that outperforms the original schema by adding two new mechanisms: redundancy channels and feedback error correction. 相似文献
63.
64.
Gerardo Iñiguez Rafael A. Barrio János Kertész Kimmo K. Kaski 《Computer Physics Communications》2011,182(9):1866-1869
In a previous paper we proposed a model to study the dynamics of opinion formation in human societies by a co-evolution process involving two distinct time scales of fast transaction and slower network evolution dynamics. In the transaction dynamics we take into account short range interactions as discussions between individuals and long range interactions to describe the attitude to the overall mood of society. The latter is handled by a uniformly distributed parameter α, assigned randomly to each individual, as quenched personal bias. The network evolution dynamics is realised by rewiring the societal network due to state variable changes as a result of transaction dynamics. The main consequence of this complex dynamics is that communities emerge in the social network for a range of values in the ratio between time scales. In this paper we focus our attention on the attitude parameter α and its influence on the conformation of opinion and the size of the resulting communities. We present numerical studies and extract interesting features of the model that can be interpreted in terms of social behaviour. 相似文献
65.
Nowadays multi-core processors can be found everywhere. It is well known that one way of improving performance is by parallelization. In this paper we propose a parallelization strategy for Java using algebraic laws. We perform an experiment with two benchmarks and show that our strategy produces a gain similar to a specialized parallel version provided by the Java Grande Benchmark (JGB). 相似文献
66.
Efrén Carrera J. Alejandro González José Talamantes-Silva Rafael Colás 《Metallurgical and Materials Transactions B》2011,42(5):1023-1030
The mechanical properties of cast aluminum alloys can be affected by the delay in time involved between the stages of rapid cooling after solubilization (quenching) and aging. This effect was studied on samples from three different Al-Si alloys that were cast with a wide range of microstructures. It was found that the parameter that exerts the highest influence on the mechanical properties is the degree of microstructural refining, which is referred to dendrite arm spacing, as a finer structure enhances the strength and ductility. It was found that the yield strength and total elongation, and to a lesser extend the ultimate tensile strength, are affected by the delay in time. The material that was treated to the peak-aged condition was found to be more susceptible to the reduction in mechanical properties with the increase in the delay in time. 相似文献
67.
Rafael Libanori Frédéric H.L. MünchDavi M. Montenegro André R. Studart 《Composites Science and Technology》2012
Hierarchically reinforced structures are widespread in nature but less common among man-made materials. In this paper, we show that polyurethane-based thermoplastic polymers can be hierarchically reinforced with laponite nanoplatelets and alumina microplatelets to reach strength and elastic modulus that are, respectively, 7- and 29-fold higher than that of the pure polymer matrix (91.7 MPa and 6.97 GPa, respectively). We find that the selective reinforcement of the polyurethane hard domains with laponite nanoplatelets is key to keep the polymer matrix sufficiently ductile for the incorporation of high concentrations of alumina microplatelets. Effective reinforcement of the polymer with microplatelets of different surface chemistries was only possible after annealing the composite at 130 °C to promote strong bonding at the oxide/polymer interface. Large-area composite films and bulk parts exhibiting good alignment of alumina microplatelets were obtained through conventional tape-casting. The concept of hierarchical reinforcement demonstrated here can be explored to obtain composite materials covering a wide range of mechanical properties using only a few reinforcing building blocks within the same polymer matrix. 相似文献
68.
Yifei Li Akshay Singh Kate Reidy Seong Soon Jo Frances M. Ross Rafael Jaramillo 《Advanced functional materials》2020,30(36)
The synthesis of large‐area TiS2 thin films is reported at temperatures as low as 500 °C using a scalable two‐step method of metal film deposition followed by sulfurization in an H2S gas furnace. It is demonstrated that the lowest‐achievable sulfurization temperature depends strongly on the oxygen background during sulfurization. This dependence arises because Ti? O bonds present a substantial kinetic and thermodynamic barrier to TiS2 formation. Lowering the sulfurization temperature is important to make smooth films, and to enable integration of TiS2 and related transition metal dichalcogenides—including metastable phases and alloys—into device technology. 相似文献
69.
Thin-film transistors (TFTs) fabricated in polysilicon films deposited by plasma enhanced chemical vapor deposition (PECVD)
were characterized. The transistors were fabricated using a low temperature process (i.e., <- 700° C). The characteristics of the devices were found to improve as the deposition temperature of the polysilicon film
increased. The best characteristics (μ
FE of 15 cm2/V
s andV
TH of 2.2V) were measured in the devices fabricated in the film deposited at 700° C. The devices fabricated in the PECVD polysilicon
films were compared to those fabricated in polysilicon films deposited by thermal CVD in the same reactor in order to decouple
the effect of the plasma. A coplanar electrode structure TFT with adequate characteristics (μ
FE of 8 cm2/V
s) was also demonstrated in the PECVD polysilicon films. 相似文献
70.
Selective deposition of TiSi2 on oxide patterned wafers using low pressure chemical vapor deposition
The selective deposition of titanium disilicide was investigated using a cold-wall, low pressure chemical vapor deposition
(LPCVD) technique with silane and titanium tetrachloride as the silicon and titanium sources, respectively. In-situ hydrogen
plasma effectively cleaned the silicon wafer surface for deposition of C54 TiSi2 at 760‡ C with full selectivity. A new method using a plasma only at the beginning of the deposition of the silicide further
decreased the temperature to 680‡ C without losing selectivity. The result was a fine grained film probably due to the enhanced
nucleation rate of the silicide. Cross-sectional TEM studies showed that the silicide grew into the silicon substrate, suggesting
significant silicon consumption. The silicon substrate, consequently, seems to play a major role in the silicide formation.
Silane, on the other hand, plays a minor role as a silicon source but does act as a scavenger of HC1 in the gas or on the
silicide surface. 相似文献