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The energy-efficient deployment of small cells helps to reduce environmental pollution in an ultra-dense network. In contrast, demand for massive connectivity and higher data rate are the promise of the present cellular system and small cell networks. Hence, energy consumption is reduced if base stations are optimally used. One way to improve the energy efficiency is by shutting down the redundant BSs while sustaining the Quality of Service for each user. This paper proposes an efficient cell modeling (ECM) algorithm for small cell formation, and binary particle swarm optimization-based small cell deployment (BPSD) to optimize the deployment of small base stations in the small cell network. The small base stations (s-BSs) exist in two modes: active and sleep which is decided by the proposed algorithm without compromising the network performance. The proposed ECM and BPSD algorithms are implemented and evaluated in MATLAB. The results demonstrate that the proposed approaches improve the energy efficiency and connectivity in the ultra-dense small cell network.
相似文献Significance: Poor aqueous solubility of PGH was overcome by the design of SDs. Level A correlation demonstrated between in vitro release and bioavailability of PGH, suggest its biowaiver potential.
Methods: The effects of semicrystalline copolymers (poloxamer 407 and gelucire 50/13) and methods of preparations on dissolution behavior, in vivo performance, and stability of PGH SDs were investigated. All the SDs were characterized by FTIR, TGA, DSC, XRD, and SEM.
Results: FTIR and TGA showed the compatibility with the polymers. The significant change in melting pattern of the PGH observed in the DSC thermograms supported by XRD patterns & SEM indicated a change from a crystalline to an amorphous state. Gelucire 50/13 was observed to have greater ability to form SDs than poloxamer 407 in solvent evaporation method (SM). Prevention of recrystallization during storage suggested stability of the formulation. Gelucire 50/13 based SD, prepared by SM remarkably increased the dissolution within 15?min (87.27?±?2.25%) and was supported by dissolution parameters (Q15, IDR, RDR, % DE, f1, f2). These SDs showed pH-dependent solubility. In vivo test showed significantly (p?<?.05) higher AUC0–t and Cmax, which were about 3.17 and 4.34 times that of the pure drug respectively.
Conclusion: Gelucire 50/13 was found to be a suitable carrier for SM for preparation of SDs of PGH as evident from increased dissolution and bioavailability. 相似文献
Every year thousands of urban and industrial fires occur, which leads to the destruction of infrastructure, buildings, and loss of lives. One of the reasons behind this is the delayed transmission of information to the fire station and the nearer hospitals for ambulance service as the transmission of information is dependent on observer at the location where the fire is caught and cellular network. This paper proposed an automated routing protocol for the urban vehicular ad-hoc network to send the information from the location where the fire is caught to the nearest fire stations and hospitals with optimum service time. This transmission of information involves Road Side Unit (RSU) at the junction and the vehicles present in the transmission path. Selection of route to transmit faulty vehicle information from the RSU to the required faulty vehicle is based on a parameter called path value. The computation of path value is done by the attributes such as expected End To End (E2E) delay, the shortest distance to destination, the density of vehicle between the junctions, and attenuation. From the current junction, the selection of the next junction is based on minimum path value. The proposed routing protocol considers the performance parameters such as E2E delay, total service time (TST), number of network fragments or network gaps, number of hops, and attenuation for the propagation path for the evaluation of the proposed methodology. The proposed routing algorithm is implemented through OmNet++ and SUMO. Results obtained for the proposed routing protocol is compared with three existing VANET protocols (GSR, A-STAR, and ARP) in terms of End To End delay, number of hops, number of vehicular gaps, and Total Service Time (TST).
相似文献Most of the researches on error rate analysis of direct sequence spread spectrum (DSSS-CDMA) systems assume that the synchronization is perfect. However, in practice, the synchronization is often imperfect due to various effects of channel parameters such as noise and fading. The degree of imperfection further increases due to jamming attacks. The present study, therefore, derives new expressions to compute the probability of error in DSSS-CDMA systems under imperfect synchronisation. It is assumed that the channel is wideband and is subjected to various jamming attacks. A new parameter, called as probability of successful synchronization, was introduced which includes the effects of both the probability of false alarm and detection under fast and slow jammers. Monte Carlo simulations were conducted in MATLAB to establish the validity of the derived mathematical expressions.
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