Hydrothermally grown mixed ternary nickel ferrite oxides as hybrid battery-type electrodes

Journal of Materials Science: Materials in Electronics - In this paper, a facile hydrothermal method is introduced to synthesize MNiFe-oxide (MNFOs: M?=?non, Cu, Co, Mg, Zn or Al)...     

Hybrid Probabilistic Risk Assessment Using Fuzzy FTA and Fuzzy AHP in a Process Industry

Journal of Failure Analysis and Prevention - There are many available techniques which are widely used for failure probability analysis. Fault tree analysis (FTA) is a well-known method to identify...     

Acquiring and Sharing Tacit Knowledge in Failure Diagnosis Analysis Using Intuitionistic and Pythagorean Assessments

Journal of Failure Analysis and Prevention - Nowadays knowledge management has received a considerable attention from both academics and industrial sectors, and expert knowledge is recognized as...     

Introducing a heuristic approach to enhance the reliability of system safety assessment

Probabilistic risk assessment techniques are the important tools which can considerably improve the safety performance of the studied system and reduce the risk to an acceptable level. Typically, decision‐making process is an important part of risk assessment methods that accordingly bring the ambiguity inside. Decision makers as experts commonly express their subjective opinions about the occurrence of the root events in order to obtain the probability of the undesired event. Subsequently, the critical root events are identified, and possible intervention is performed to reduce the probability of the critical events. However, the serious point is the viability of the obtained probabilities and priority ranking of the critical events. In this study, a heuristic optimization model of linear mathematical programming using triangular intuitionistic fuzzy number (TrIFN) is proposed to obtain the feasible, optimum, and reliable results compared with available methods. The Spearman correlation is performed to examine the reliability and behavior of the proposed model. In order to show the effectiveness of the proposed approach, it is applied on a real case study. The application of the model confirms its robustness to prioritize critical root events over the conventional one.     

Transparent magnetic oxide thin films of Fe3O4 on glass

Transparent magnetic oxide (TMO) thin films of magnetite (Fe₃O₄) were grown on top of a (Zn,Al)O transparent conducting oxide on a glass substrate. The polycrystalline magnetite thin films show the typical Raman spectrum of Fe₃O₄, a sharp Verwey transition at 120 K and hysteretic behavior. The highest achieved average transmittance in the visible range (400-800 nm) for the entire multilayer was slightly below 80%. TMOs permit the inclusion of magnetic functionalities into transparent electronics. Our results show that TMOs can be successfully used to add magnetic functionalities to transparent conducting oxides.     

Biosynthesis of SeNPs by Mycobacterium bovis and their enhancing effect on the immune response against HBs antigens: an in vivo study

Conventional hepatitis B vaccine contains alum but is less effective to induce Th1 response. Selenium nanoparticles and Bacillus Calmette–Guerin were reported as immune modulators. In this study, SeNPs were extracted from Mycobacterium bovis and characterised. SeNPs were mixed with HBs‐Ag and administered to the mice to investigate he immune response pattern. With an addition of Se ions at a sub‐inhibitory concentration to the Sauton medium broth after 24 h, SeNPs were extracted from M. bovis and characterised by Fourier transform infrared spectroscopy, dynamic light scattering, atomic forcemicroscopy, energy dispersive X‐ray spectrum, transmission electron microscopy, and thermogravimetric analysis. Furthermore, female inbred BALB/c mice were injected subcutaneously on the first, 14th, 28th day with 100 and 200 µg doses of that SeNPs supplemented with HBs‐Ag vaccine. Later, the total antibody, isotypes of Immunoglobulin G1, Interlukin 4, and interferon‐γ were measured by enzye‐linked immunosorbent assay. The size of the SeNPs was <150 nm. Level of total antibody and immunoglobulin G2a increased significantly in the group that received 200 µg/ml nano selenium extracted from M. bovis. SeNPs in dose of 200 µg coated with organic materials of M. bovis could induce an influential immune response in relation to the conventional HBs‐Ag vaccine.Inspec keywords: selenium, nanoparticles, nanofabrication, microorganisms, Fourier transform spectra, infrared spectra, light scattering, atomic force microscopy, X‐ray chemical analysis, transmission electron microscopy, thermal analysis, nanomedicineOther keywords: biosynthesis, selenium nanoparticles, Mycobacterium bovis, enhnced immune response, HBs antigens, Bacillus Calmette‐Guerin, immune modulators, biogenic SeNPs, immune response pattern, Sauton medium broth, Fourier transform infrared spectroscopy, dynamic light scattering, atomic force microscopy, energy dispersive X‐ray spectrum, transmission electron microscopy, thermogravimetric analysis, female inbred BALB/c mice, antibody, IgG1 isotype, IgG2a isotype, IL₄ isotype, interferon‐γ, enzyme‐linked immunosorbent assay, bacterium, time 24 h, time 14 day, time 28 day, Se     

Estimating Young's modulus of zona pellucida by micropipette aspiration in combination with theoretical models of ovum

The zona pellucida (ZP) is the spherical layer that surrounds the mammalian oocyte. The physical hardness of this layer plays a crucial role in fertilization and is largely unknown because of the lack of appropriate measuring and modelling methods. The aim of this study is to measure the biomechanical properties of the ZP of human/mouse ovum and to test the hypothesis that Young''s modulus of the ZP varies with fertilization. Young''s moduli of ZP are determined before and after fertilization by using the micropipette aspiration technique, coupled with theoretical models of the oocyte as an elastic incompressible half-space (half-space model), an elastic compressible bilayer (layered model) or an elastic compressible shell (shell model). Comparison of the models shows that incorporation of the layered geometry of the ovum and the compressibility of the ZP in the layered and shell models may provide a means of more accurately characterizing ZP elasticity. Evaluation of results shows that although the results of the models are different, all confirm that the hardening of ZP will increase following fertilization. As can be seen, different choices of models and experimental parameters can affect the interpretation of experimental data and lead to differing mechanical properties.     

Implementation of design of experiments approach for the micronization of a drug with a high brittle–ductile transition particle diameter

Objective: To optimize air-jet milling conditions of ibuprofen (IBU) using design of experiment (DoE) method, and to test the generalizability of the optimized conditions for the processing of another non-steroidal anti-inflammatory drug (NSAID).

Methods: Bulk IBU was micronized using an Aljet mill according to a circumscribed central composite (CCC) design with grinding and pushing nozzle pressures (GrindP, PushP) varying from 20 to 110?psi. Output variables included yield and particle diameters at the 50th and 90th percentile (D₅₀, D₉₀). Following data analysis, the optimized conditions were identified and tested to produce IBU particles with a minimum size and an acceptable yield. Finally, indomethacin (IND) was milled using the optimized conditions as well as the control.

Results: CCC design included eight successful runs for milling IBU from the ten total runs due to powder “blowback” from the feed hopper. DoE analysis allowed the optimization of the GrindP and PushP at 75 and 65?psi. In subsequent validation experiments using the optimized conditions, the experimental D₅₀ and D₉₀ values (1.9 and 3.6?μm) corresponded closely with the DoE modeling predicted values. Additionally, the optimized conditions were superior over the control conditions for the micronization of IND where smaller D₅₀ and D₉₀ values (1.2 and 2.7?μm vs. 1.8 and 4.4?μm) were produced.

Conclusion: The optimization of a single-step air-jet milling of IBU using the DoE approach elucidated the optimal milling conditions, which were used to micronize IND using the optimized milling conditions.     

The Application of Bow-Tie Method in Hydrogen Sulfide Risk Management Using Layer of Protection Analysis (LOPA)

Safety systems need to be used in strong and stable ways to achieve the objectives and goals of organizations. The main role of safety systems is highlighted ever than before in maintaining personnel health, environmental protection and improves the reputation of the organizations. Proper functioning of safety system depends on the reliability and the failure probability of the system, which determines the integrated system safety. In this regard, this study aimed to H₂S risk management using bow-tie model with an emphasis on Layer of Protection Analysis (LOPA). An oil processing and gas injection plant is selected as a case of study with considering the high concentration of H₂S (130,000 ppm) as well as very high pressure of gas injection (410 bars). This work commences when hazardous regions is categorized according to H₂S gas leakage resources which followed by H₂S risk assessment (bow-tie model). In the following stage, intelligent safety systems were investigated as one of the LOPAs. Thus, the elements of intelligent safety systems are specified. Based upon the software-defined logic, block diagrams were determined. Then, Probability of Failure on Demand (PFD) and Safety Integrity Level (SIL) were attained. PFD of block diagrams was calculated, and corresponding SIL was obtained using Reliability Block Diagram and the relationships between PFD and reliability. As a result, each of elements or block diagrams was considered the weak points. Accordingly, solutions were proposed to reduce the adverse effects and promote SIL to improve safety performance of plant.     

Slip MHD liquid flow and heat transfer over non-linear permeable stretching surface with chemical reaction

In the present study the magnetohydrodynamic (MHD) liquid flow and heat transfer over non-linear permeable stretching surface has been presented in the presence of chemical reactions and partial slip. By means of proper similarity variables, the fundamental equations of the boundary layer are transformed to ordinary differential equations which for the fixed values of the x-coordinate along the plate local similarity solution would be valid appropriately. The ordinary differential equations are solved numerically using an explicit Runge–Kutta (4, 5) formula, the Dormand–Prince pair and shooting method. As a result, the velocity profiles, the concentration profiles, temperature profiles, the wall shear stress, the local Sherwood number and the local Nusselt number for the various values of the involved parameters of the problem are presented and discussed in details.