Analytical modeling of grinding wheel loading phenomena

Wheel surface condition plays an important role in the grinding operation. Grinding wheel loading, meaning chip accumulation in the space between grains, leads to deteriorating wheel cutting ability and causes excessive force and temperature. This paper presents an analytical model of wheel loading phenomena as a function of cutting parameters, wheel structure, and material properties. The model is based on the adhesion of workpiece material to abrasive grain surface. It is validated by experimental results from grinding nickel-based superalloy with cubic boron nitride vitrified wheel. This model considers wheel specifications including abrasive grains size and the number of cutting edges. Cutting parameters and process temperature are the other determinant factors. On the basis of this model and empirical results, the effects of the various process parameters are presented.     

Improving the surface quality in wire electrical discharge machined specimens by removing the recast layer using magnetic abrasive finishing method

This study explores the feasibility of removing the recast layer formed on aluminum alloy cylindrical specimens machined by wire electrical discharge machining (WEDM) by using magnetic abrasive finishing (MAF). The WEDM is a thermal machining process capable of accurately machining parts with high hardness or complex shapes. The sparks produced during the WEDM process melt the metal’s surface. The molten material undergoes ultra-rapid quenching and forms a layer on the surface defined as recast layer. The recast layer may be full of craters and microcracks which reduce service life of materials tremendously, especially under fatigue loads in corrosive environments. This investigation demonstrates that MAF process, can improve the quality of WEDM machined surfaces effectively by removing the recast layer. The present work studies the effect of some parameters, i.e., linear speed, working gap, abrasive particle size, and finishing time on surface roughness and recast layer thickness using full factorial analysis. Three-level full factorial technique is used as design of experiments for studying the selected factors. In order to indicate the significant factors, the analysis of variance has been used. In addition, an equation based on regression analysis is presented to indicate the relationship between surface roughness and recast layer thickness of cylindrical specimens and finishing parameters. Experimental results show the influence of MAF process on recast layer removal and surface roughness improvement.     

Properties of the slab modes in photonic crystal optical waveguides

We show that by placing a slab of semiconductor material between two photonic bandgap (PBG) mirrors, waveguide modes at frequencies out of the PBG can be obtained. These modes are similar to the modes of a conventional dielectric slab waveguide. Using these modes, we can obtain very good coupling between a PBG waveguide and a dielectric slab waveguide with similar slab properties. We discuss the properties of these slab modes and outline the guideline for the optimization of the PBG waveguides based on these properties     

A time-varying quadratic programming for online clustering of streaming data

An online clustering method based on a time-varying quadratic programming is proposed which can precisely detect streaming data clustering structure when no assumption is desired on the shape and density of data classes. In the proposed method, online clustering is achieved through simulating some dynamical equations which yield optimum solution of the time-varying quadratic programming over time. A new framework is also proposed which efficiently permits streaming data clustering based on a relatively small and renewable dataset. This framework reduces the need for incoming data storage memory to a small and independent of original data size. The performance of the proposed method is evaluated through the experiments using synthetic data as well as the KDD cup 99 dataset. The results illustrate higher performance of the proposed method in comparison with a range of benchmark methods.     

Histological assessment of follicular delivery of flutamide by solid lipid nanoparticles: potential tool for the treatment of androgenic alopecia

Abstract

Context: Flutamide is a potent anti-androgen with the several unwanted side effects in systemic administration, therefore, it has attracted special interest in the development of topically applied formulations for the treatment of androgenic alopecia.

Objective: The purpose of this study was to prepare and characterize the solid lipid nanoparticles (SLNs) of Flutamide for follicular targeting in the treatment of the androgenic alopecia.

Methods: Flutamide-loaded SLNs, promising drug carriers for topical application were prepared by hot melt homogenization method. Drug permeation and accumulation in the exercised rat skin and histological study on the male hamsters were performed to assess drug delivery efficiency in vitro and in vivo, respectively.

Results: The optimized Flutamide-loaded SLNs (size 198?nm, encapsulation efficiency percentage 65% and loading efficiency percentage 3.27%) exhibited a good stability during the period of at least 2 months. The results of X-ray diffraction showed Flutamide amorphous state confirming uniform drug dispersion in the SLNs structure. Higher skin drug deposition (1.75 times) of SLN formulation compared to Flutamide hydroalcoholic solution represented better localization of the drug in the skin. The in vivo studies showed more new hair follicle growth by utilizing Flutamide-loaded SLNs than Flutamide hydroalcoholic solution which could be due to the higher accumulation of SLNs in the hair follicles as well as slowly and continues release of the Flutamide through the SLNs maximizing hair follicle exposure by antiandrogenic drug.

Conclusion: It was concluded Flutamide-loaded SLN formulation can be used as a promising colloidal drug carriers for topical administration of Flutamide in the treatment of androgenic alopecia.     

Experimental study of the effect of zeolite 4A treated with magnesium hydroxide on the characteristics and gas‐permeation properties of polysulfone‐based mixed‐matrix membranes

Nowadays, new methods for gas‐separation processes are being quickly developed. The separation of CH₄/CO₂ and CH₄/H₂ is usually the subject of most related research studies, especially in the membrane gas‐separation process, because of their important role in industry. In this study, we attempted to improve the separation properties of a polysulfone/zeolite 4A mixed‐matrix membrane by modifying the zeolite particle surface. The method included a simple ion‐exchange reaction of magnesium chloride with ammonium hydroxide that yielded the formation and precipitation of magnesium hydroxide whiskers on the surface of the zeolites. The whiskers could omit most of the nonselective voids by interlocking the polymer chains through them and, consequently, improve the permeability, selectivity, and elastic modulus of the membranes. X‐ray diffraction, energy‐dispersive X‐ray spectroscopy, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, and dynamic mechanical analysis proved all the changes recorded after the particle and membrane treatments. SEM images showed the petal‐like morphology of the whiskers that formed on the surface of the particles after the reaction against the smooth surface of the untreated zeolite. At a 30 wt % loading of particles in the polymeric matrix, the selectivities for H₂/CH₄ and CO₂/CH₄ increased by 69 and 56%, respectively; in contrast, the H₂ and CO₂ permeabilities decreased by 2.5 and 10%, respectively. The modulus of elasticity for the treated membrane also increased by 14 and 30% compared to those of the pure and untreated membranes, respectively. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133, 44329.     

Response surface predictions of the viscoelastic properties of vapor‐grown carbon nanofiber/vinyl ester nanocomposites

A full factorial design of experiments and response surface methodology were used to investigate the effects of formulation, processing, and operating temperature on the viscoelastic properties of vapor‐grown carbon nanofiber (VGCNF)/vinyl ester (VE) nanocomposites. Factors included VGCNF type (pristine, oxidized), use of a dispersing agent (DA) (no, yes), mixing method (ultrasonication, high‐shear mixing, and a combination of both), VGCNF weight fraction (0.00, 0.25, 0.50, 0.75, and 1.00 parts per hundred parts resin (phr)), and temperature (30, 60, 90, and 120°C). Response surface models (RSMs) for predicting storage and loss moduli were developed, which explicitly account for the effect of complex interactions between nanocomposite design factors and operating temperature on resultant composite properties; such influences would be impossible to assess using traditional single‐factor experiments. Nanocomposite storage moduli were maximized over the entire temperature range (～20% increase over neat VE) by using high‐shear mixing and oxidized VGCNFs with DA or equivalently by employing pristine VGCNFs without DA at ～0.40 phr of VGCNFs. Ultrasonication yielded the highest loss modulus at ～0.25 phr of VGCNFs. The RSMs developed in this investigation may be used to design VGCNF‐enhanced VE matrices with optimal storage and loss moduli for automotive structural applications. Moreover, a similar approach may be used to tailor the mechanical, thermal, and electrical properties of nanomaterials over a range of anticipated operating environments. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013     

Molecular dynamics simulations of oxidized vapor-grown carbon nanofiber surface interactions with vinyl ester resin monomers

Surface oxidation effects on the liquid vinyl ester (VE) monomer distributions near two oxidized vapor-grown carbon nanofiber (VGCNF) surfaces were studied using molecular dynamics simulations. Two overlapping graphene sheets containing oxygenated functional groups represented the oxidized VGCNF surfaces. Two liquid VE bisphenol-A dimethacrylates (designated VE1 and VE2, respectively) and styrene constituted the resin. Temporally and spatially averaged relative monomer concentrations, calculated in a direction away from the oxidized graphene surfaces, showed increased styrene and VE1 concentrations. Monomer molar ratios found within a 10 Å thick region adjacent to the oxidized graphene sheets were substantially different from those in the bulk resin. Curing should result in the formation of a very thin interphase region of different composition. The crosslink structure of such an interphase will be distinct from that of an unoxidized VGCNF surface. The enhanced VE1 concentration near this oxidized surface should give a higher crosslink density, leading to a stiffer interphase than that adjacent to unoxidized VGCNF surfaces. VGCNF–matrix adhesion may also be modified by the different interphase monomer molar ratios. These studies may facilitate multiscale material design by providing insight into carbon nanofiber–matrix interactions leading to improved macroscale composite properties.     

Secondary grating formation by readout at Bragg-null incidence

We show that when a dynamic hologram is read out by illumination at the Bragg nulls of a previously recorded grating the diffracted beam inside the medium can result in the recording of two secondary gratings that alter the final selectivity curve. This is confirmed experimentally. This effect can cause cross talk in hologram multiplexing that is stronger than interpage cross talk when a small number of holograms with high diffraction efficiencies are multiplexed.