AB9: A neural processor for inference acceleration

We present AB9, a neural processor for inference acceleration. AB9 consists of a systolic tensor core (STC) neural network accelerator designed to accelerate artificial intelligence applications by exploiting the data reuse and parallelism characteristics inherent in neural networks while providing fast access to large on‐chip memory. Complementing the hardware is an intuitive and user‐friendly development environment that includes a simulator and an implementation flow that provides a high degree of programmability with a short development time. Along with a 40‐TFLOP STC that includes 32k arithmetic units and over 36 MB of on‐chip SRAM, our baseline implementation of AB9 consists of a 1‐GHz quad‐core setup with other various industry‐standard peripheral intellectual properties. The acceleration performance and power efficiency were evaluated using YOLOv2, and the results show that AB9 has superior performance and power efficiency to that of a general‐purpose graphics processing unit implementation. AB9 has been taped out in the TSMC 28‐nm process with a chip size of 17 × 23 mm². Delivery is expected later this year.     

Printable Semiconductors for Backplane TFTs of Flexible OLED Displays

Studies on printable semiconductors and technologies have increased rapidly over recent decades, pioneering novel applications in many fields, such as energy, sensing, logic circuits, and information displays. The newest display technologies are already turning to metal oxide semiconductors, i.e., indium gallium zinc oxide, for the improvements needed to drive active matrix organic light‐emitting diodes. Convenience and portability will be realized with flexible and wearable displays in the future. This report summarizes recent progress on the development of solution‐processed thin film transistors, especially those deposited at low temperatures for next‐generation flexible smart displays. The first part provides an overview on the history and current status of displays. Then, recent advances in state‐of‐the‐art solution‐processed transistors based on different semiconductors are presented, including metal oxides, organic materials, perovskites, and carbon nanotubes. Finally, conclusions are drawn and the remaining challenges and future perspectives are discussed.     

Toward Artificial Cells: Novel Advances in Energy Conversion and Cellular Motility

The demand to discover every single cellular component has been continuously increasing along with the development of biological techniques. The bottom‐up approach to construct a cell‐mimicking system from well‐defined and tunable compositions is accelerating, with the ultimate goal of comprehending a biological cell. From among the available techniques, the artificial cell has been increasingly recognized as one of the most powerful tools for building a cell‐like system from scratch. This review summarizes the development of artificial cells, from a pure giant unilamellar vesicle (GUV) to a controllable, self‐fueled proteoliposome, both of which are highly compartmentalized. The basic components of an artificial cell, as well as the optimal conditions required for successful, reproducible GUV formation and protein reconstitution, are discussed. Most importantly, progress in studying the metabolic reactions in and the motility of a reconstituted artificial cell are the main focus of the review. The ability to perform a complicated reaction cascade in a controllable manner is highlighted as a promising perspective to obtaining an autonomous and movable GUV.     

A Multi‐Functional Highly Efficient Upconversion Luminescent Film with an Array of Dielectric Microbeads Decorated with Metal Nanoparticles

Upconversion nanoparticles (UCNPs) have been integrated with photonic platforms to overcome the intrinsically low quantum efficiency limit of upconversion luminescence (UCL). However, platforms based on thin films lack transferability and flexibility, which hinders their broader and more practical application. A plasmonic structure is developed that works as a multi‐functional platform for flexible, transparent, and washable near‐infrared (NIR)‐to‐visible UCL films with ultra‐strong UCL intensity. The platform consists of dielectric microbeads decorated with plasmonic metal nanoparticles on an insulator/metal substrate. Distinct improvements in NIR confinement, visible light extraction, and boosted plasmonic effects for upconversion are observed. With weak NIR excitation, the UCL intensity is higher by three orders of magnitude relative to the reference platform. When the microbeads are organized in a square lattice array, the functionality of the platform can be expanded to wearable and washable UCL films. The platform can be transferred to transparent, flexible, and foldable films and still emit strong UCL with a wide viewing angle.     

Thermally Controlled,Active Imperceptible Artificial Skin in Visible‐to‐Infrared Range

Cephalopods’ extraordinary ability to hide into any background has inspired researchers to reproduce the intriguing ability to readily camouflage in the infrared (IR) and visible spectrum but this still remains as a conundrum. In this study, a multispectral imperceptible skin that enables human skin to actively blend into the background both in the IR‐visible integrated spectrum only by simple temperature control with a flexible bi‐functional device (active cooling and heating) is developed. The thermochromic layer on the outer surface of the device, which produces various colors based on device surface temperature, expands the cloaking range to the visible spectrum (thus visible‐to‐IR) and ultimately completes day‐and‐night stealth platform simply by controlling device temperature. In addition, the scalable pixelization of the device allows localized control of each autonomous pixel, enabling the artificial skin surface to adapt to the background of the sophisticated pattern with higher resolution and eventually heightening the level of imperceptibility. As this proof‐of‐concept can be directly worn and conceals the human skin in multispectral ranges, the work is expected to contribute to the development of next‐generation soft covert military wearables and perhaps a multispectral cloak that belongs to cephalopods or futuristic camouflage gadgets in the movies.     

Nonlinear bilateral teleoperators under event‐driven communication with constant time delays

Bilateral teleoperation systems provide a platform for human operators to remotely manipulate slave robots in engaging various tasks in remote environments. Most of the previous studies in bilateral teleoperation were developed under continuous transmission or periodic communication with fixed data exchanging rates. This paper presents control schemes for bilateral teleoperation systems using nonperiodic event‐driven communication. By using P‐like and PD‐like controllers, this study proposes triggering conditions for teleoperators to reduce network access frequency so that robots only transmit output signals when necessary. Stability and position tracking of the control system are studied, and nonzero minimum interevent time is guaranteed. The proposed event‐driven teleoperation is studied with a velocity estimator to avoid the requirement of velocity information in the controller and triggering condition. Without velocity measurements, the boundedness of tracking errors and stability are ensured for teleoperation systems under event‐driven communication. Simulations and experiments are illustrated to validate the performance of the proposed event‐driven teleoperation systems.     

Design and Experimental Evaluation of a Discrete‐time ASPR‐based Adaptive Output Feedback Control System Using FRIT

This paper describes the design of an adaptive output feedback control system in discrete‐time, based on almost strictly positive real (ASPR)‐ness with a feedforward input. It is well‐known that an adaptive output feedback control system based on ASPR conditions can achieve asymptotic stability via a constant feedback gain. Unfortunately, most realistic systems are not ASPR because of the severe conditions. The introduction of a parallel feedforward compensator (PFC) is an efficient way to alleviate such restrictions. However, the problem remains that there exists a steady state error between the output of the augmented system and the output of the original system. The proposed scheme provides a strategy wherein the feedforward input is utilized such that the steady state error is removed. Furthermore, the fictitious reference iterative tuning (FRIT) approach is employed to determine the control parameters using one‐shot input/output experimental data directly, without prior information about the control system. This paper explains how the FRIT approach is applied in designing an adaptive output feedback control system. The effectiveness of the proposed scheme is confirmed experimentally, by using a motor application.     

Mass Cytometry and Single‐Cell RNA‐seq Profiling of the Heterogeneity in Human Peripheral Blood Mononuclear Cells Interacting with Silver Nanoparticles

Understanding the interactions between nanoparticles (NPs) and human immune cells is necessary for justifying their utilization in consumer products and biomedical applications. However, conventional assays may be insufficient in describing the complexity and heterogeneity of cell–NP interactions. Herein, mass cytometry and single‐cell RNA‐sequencing (scRNA‐seq) are complementarily used to investigate the heterogeneous interactions between silver nanoparticles (AgNPs) and primary immune cells. Mass cytometry reveals the heterogeneous biodistribution of the positively charged polyethylenimine‐coated AgNPs in various cell types and finds that monocytes and B cells have higher association with the AgNPs than other populations. scRNA‐seq data of these two cell types demonstrate that each type has distinct responses to AgNP treatment: NRF2‐mediated oxidative stress is confined to B cells, whereas monocytes show Fcγ‐mediated phagocytosis. Besides the between‐population heterogeneity, analysis of single‐cell dose–response relationships further reveals within‐population diversity for the B cells and naïve CD4⁺ T cells. Distinct subsets having different levels of cellular responses with respect to their cellular AgNP doses are found. This study demonstrates that the complementary use of mass cytometry and scRNA‐seq is helpful for gaining in‐depth knowledge on the heterogeneous interactions between immune cells and NPs and can be incorporated into future toxicity assessments of nanomaterials.     

Anti‐Atherogenic Effect of Stem Cell Nanovesicles Targeting Disturbed Flow Sites

Atherosclerosis development leads to irreversible cascades, highlighting the unmet need for improved methods of early diagnosis and prevention. Disturbed flow formation is one of the earliest atherogenic events, resulting in increased endothelial permeability and subsequent monocyte recruitment. Here, a mesenchymal stem cell (MSC)‐derived nanovesicle (NV) that can target disturbed flow sites with the peptide GSPREYTSYMPH (PREY) (PMSC‐NVs) is presented which is selected through phage display screening of a hundred million peptides. The PMSC‐NVs are effectively produced from human MSCs (hMSCs) using plasmid DNA designed to functionalize the cell membrane with PREY. The potent anti‐inflammatory and pro‐endothelial recovery effects are confirmed, similar to those of hMSCs, employing mouse and porcine partial carotid artery ligation models as well as a microfluidic disturbed flow model with human carotid artery‐derived endothelial cells. This nanoscale platform is expected to contribute to the development of new theragnostic strategies for preventing the progression of atherosclerosis.     

Mobility Engineering in Vertical Field Effect Transistors Based on Van der Waals Heterostructures

Vertical integration of 2D layered materials to form van der Waals heterostructures (vdWHs) offers new functional electronic and optoelectronic devices. However, the mobility in vertical carrier transport in vdWHs of vertical field‐effect transistor (VFET) is not yet investigated in spite of the importance of mobility for the successful application of VFETs in integrated circuits. Here, the mobility in VFET of vdWHs under different drain biases, gate biases, and metal work functions is first investigated and engineered. The traps in WSe₂ are the main source of scattering, which influences the vertical mobility and three distinct transport mechanisms: Ohmic transport, trap‐limited transport, and space‐charge‐limited transport. The vertical mobility in VFET can be improved by suppressing the trap states by raising the Fermi level of WSe₂. This is achieved by increasing the injected carrier density by applying a high drain voltage, or decreasing the Schottky barrier at the graphene/WSe₂ and metal/WSe₂ junctions by applying a gate bias and reducing the metal work function, respectively. Consequently, the mobility in Mn vdWH at +50 V gate voltage is about 76 times higher than the initial mobility of Au vdWH. This work enables further improvements in the VFET for successful application in integrated circuits.