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101.
Critically selected thermodynamic data have been used for the calculation of equilibrium conditions in the vanadium-water system at 298·15K. Potential-pH diagrams for concentrations of 10° and 10?2gm atoms vanadium per 1000 gm water and log concentration-pH diagrams for each of the stable oxidation states are presented. 相似文献
102.
Aaron D. Krabill Hao Chen Dr. Sajjad Hussain Dr. Chao Feng Dr. Ammara Abdullah Prof. Chittaranjan Das Dr. Uma K. Aryal Prof. Carol Beth Post Prof. Michael K. Wendt Prof. Paul J. Galardy Prof. Daniel P. Flaherty 《Chembiochem : a European journal of chemical biology》2020,21(5):712-722
The deubiquitinase (DUB) ubiquitin C-terminal hydrolase L1 (UCHL1) is expressed primarily in the central nervous system under normal physiological conditions. However, UCHL1 is overexpressed in various aggressive forms of cancer with strong evidence supporting UCHL1 as an oncogene in lung, glioma, and blood cancers. In particular, the level of UCHL1 expression in these cancers correlates with increased invasiveness and metastatic behavior, as well as poor patient prognosis. Although UCHL1 is considered an oncogene with potential as a therapeutic target, there remains a significant lack of useful small-molecule probes to pharmacologically validate in vivo targeting of the enzyme. Herein, we describe the characterization of a new covalent cyanopyrrolidine-based UCHL1 inhibitory scaffold in biochemical and cellular studies to better understand the utility of this inhibitor in elucidating the role of UCHL1 in cancer biology. 相似文献
103.
Litrel Joseph Guillen Donna Post McKellar Michael 《JOM Journal of the Minerals, Metals and Materials Society》2019,71(5):1616-1622
JOM - Attractive power generation cycles from economic and sustainability considerations are highly efficient and require minimal cooling water. Air Brayton cycles (ABCs) require no cooling water;... 相似文献
104.
105.
韶山Ⅳ型电力机车谐波分析 总被引:8,自引:0,他引:8
扼要介绍了韶山Ⅳ型电力机车主电路的工作原理,根据其实际运行工况及整流电路的换相过程分析,规范地建立了主电路数学模型,导出了机车取用电流完整、准确的数学表达式,并利用快速傅立叶变换计算出机车取用电流的各次谐波分量。文中还给出了部分运行工况下的实际计算结果。 相似文献
106.
107.
Modelling Temperature,Body Size,Prey Density,and Stream Gradient Impacts on Longitudinal Patterns of Potential Production of Drift‐Feeding Trout
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In this study, we modelled idealized stream reaches using empirical hydrodynamic and bioenergetic parameters to predict how rainbow trout production depends on physical and biological variations across a downstream gradient, and we compared these downstream effects in a low and high‐gradient stream reach. We found that longitudinal production potential (i.e. net rate of energetic intake per 100 m of stream length) generally increased with increasing stream size when stream gradient was low. This was not the case, however, for high‐gradient streams, wherein maximum longitudinal production potential was associated with middle or low stream size (QMAD = 2.5 to 25 m3 s?1). Areal production potential (net rate of energetic intake per m2 of wetted stream bed) reached a maximum at low stream size (QMAD = 2.5 m3 s?1) with both high and low gradients. We also showed that high stream temperature and low drift density could potentially cause adult rainbow trout to be excluded from stream reaches with high flow. The models presented here have a stronger mechanistic basis for predicting fish production across heterogeneous stream environments and provide more nuanced predictions in response to variation in environmental features than their physical habitat‐based predecessors. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
108.
Alessandro Martucci Mirko Pasquale Massimo Guglielmi Mike Post Jean Claude Pivin 《Journal of the American Ceramic Society》2003,86(9):1638-1640
Sol–gel derived silica (SiO2 ) films doped with nickel oxide (NiO) nanocrystals were fabricated. A bifunctional ligand was used, bearing amine groups capable of coordinating the nickel ions and hydrolysable siloxane groups for anchoring the metal complex moiety to the silicate matrix. Nickel oxide nanocrystals precipitated at 500°C while the film was still porous. The nanocomposite films showed a reversible change in the optical transmittance in the VIS-NIR range when exposed to carbon monoxide gas. The effects of residual porosity, testing temperature, and carbon monoxide gas concentration on optical transmittance were studied. 相似文献
109.
垃圾邮件不仅浪费大量的网络资源,并且给用户带来很大的不便,如何有效地防范垃圾邮件,已成为网络信息安全领域的主要课题之一。本文通过对传统垃圾邮件过滤技术的分析,提出了一种基于指纹的定量过滤方法。对白名单和黑名单过滤、定时过滤、基于指纹的定量过滤和贝叶斯过滤技术进行了整合,建立了一种客户端垃圾邮件过滤系统的模型,该系统具有较高的过滤准确性,并且能适应用户的个性化需求。 相似文献
110.
本文针对公共建筑采取值班采暖运行方式进行了节能分析,公共建筑应实施供热计量收费,同时根据正常供暖与值班供暖的时间关系,供热外网实施24h供热调节,使公共建筑即节能又经济,促进全社会的建筑节能。 相似文献