Viscoelastic solid relations for the deformation of ice

A frame indifferent differential operator law relating stress, stress-rate, strain, and strain-rate is constructed to describe the qualitative features of both constant load and constant displacement rate response in uni-axial stress experiments. No lower order differential relation can describe both responses, but the two responses are not sufficient to determine the response coefficients of the relation. The jump relation is determined for a stress discontinuity applied in a general configuration. A simple initially isotropic model is proposed to investigate the effects of loading history and the anisotropy induced in a configuration following a loading-unloading cycle. Both uni-axial stress and shear cycles are treated, followed by uni-axial stress loading in different directions. The respective deformation histories are determined in the small strain approximation, and demonstrate a significant influence of the initial load cycle on response from the unloaded configuration.     

Video microscopic image processing facilitates the evaluation of light microscopic autoradiography at high magnification

Light microscopic autoradiographs of H-thymidine labelled unstained semithin sections of Xenopus laevis embryonic nuclei were examined with conventional Nomarski differential interference contrast, phase-contrast and video microscopy. Whereas at low magnification it was possible to obtain a photograph of the nuclear structure and the silver grains in one focal plain, at high magnification, with small depths of focus, a satisfactory image was not attainable. Therefore, we stored the images of the two different focus levels with a digital image processing system and combined both images by an arithmetic operation. This video microscopic technique allows the use of high magnification light microscopy with oil immersion objectives and the application of additional electronic contrast enhancing methods for an adequate and rapid analysis of light microscopic autoradiographs.     

An approach to an objective background subtraction for elemental mapping with core-edges down to 50 eV: description, evaluation and application

To image the distribution of a specific element in a specimen with an energy filtering TEM, the element-unspecific background under the core-edge has to be subtracted. The most commonly used procedure is the three-window power-law method leading to considerable systematic errors for low-energy core-edges. Here a new method is described which can be considered as a generalized difference method. Characteristic examples for element detection in biological specimens using this method are shown. The background under the core-edge can be described by one or two pre-edge windows as a polynome of third order. This function can be deduced from specimen areas that are not known to contain the element or from a second specimen used as a standard. Control experiments showed that background subtraction for on-overlapping core-edges in the low-loss region (50-200 eV) needs two pre-edge images, whereas at higher-energy losses (> 300 eV) only one pre-edge image is necessary. With the method described, objective elemental mapping becomes possible even for edges at 50-100 eV. This was proven for the M2,3-edge of iron at 60 eV. The detection of phosphorous was possible with a signal-to-noise ratio five times higher than when using the three-window method. Preliminary data showed that it should be possible to detect calcium with only one image before the edge.     

Antidepressant pharmacotherapy helps some cigarette smokers more than others.

Adult smokers (N?=?253) without clinically significant depression were randomized on a double-blind basis to receive fluoxetine (30 or 60 mg daily) or a placebo for 10 weeks in combination with cognitive-behavioral therapy (CBT). It was predicted that fluoxetine would selectively benefit smokers with higher baseline depression, nicotine dependence, and weight concern and lower self-efficacy about quitting smoking. Among those who completed the prescribed treatment regimen, baseline depression scores moderated the treatment response. Logistic regression analyses showed that 1 and 3 months after the quit date, fluoxetine increased the likelihood of abstinence, as compared with placebo, among smokers with minor depression but not among those with little or no depression. Results suggest that, as an adjunct to CBT, fluoxetine enhances cessation by selectively benefiting medication-compliant smokers who display even subclinical levels of depression. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Oxokohlenstoffe und verwandte Verbindungen. 27. Synthese von Dihydrocyclobuta[a]naphthalen-1,2-dionen und Cyclobuta[a]naphthalen-1,2-dionen durch Anellierung von Alkoxy-(1-alkenyl)benzolen mit 3-Chlor-3-cyclobuten-1,2-dion. Anwendungsbereich und Grenzen

Oxocarbons and Related Compounds. 27. Synthesis of Dihydrocyclobuta[a]naphthalene-1,2-diones and Cyclobuta[a]naphthalene-1,2-diones via Annulation of Alkoxy-(1-alkenyl)benzenes with 3-Chloro-3-cyclobutene-1,2-dione. Scope and Limitations The reaction of alkoxy-(1-alkenyl)benzenes with semisquaric chloride ( 3 ) has been investigated systematically. 1,2-Dialkoxy- and 1-alkoxy'-2-alkoxy″-4-(1-alkenyl)benzenes ( 6a–j ) and ( 11a–i ) react with 3 to give the 3,4-dihydrocyclobuta[a]naphthalene-1,2-diones ( 8a–j ) and ( 12a–i ). Treatment of the dihydrocyclobuta[a]naphthalene-1,2-diones with 1.2 equiv. bromine effects dehydrogenation and affords cyclobuta[a]naphthalene-1,2-diones ( 9a–e ) and ( 13b–f ). Any efforts to extend this annulation reaction to dimethoxy-(1-alkenyl)benzenes with the methoxy groups in other than the 1,2-positions, e. g. 14a, b, 16a, b have been unsuccessful. The reaction of 1,2,3-trimethoxy-4-(1-propenyl) [and 4-(1-butenyl)]-benzenes ( 18a ) and ( 18b ) with semisquaric chloride ( 3 ) leads to the elimination of HCl and CH₃OH and gives 5,6-dimethoxy-3-methyl [and 3-ethyl]-cyclobuta[a]naphthalene-1,2-diones ( 20a ) and ( 20b ). The reaction pathway of this novel annulation reaction is discussed.     

A W7-X experiment program editor––A usage driven development

The set-up of experiment programs for the complex fusion device Wendelstein 7-X has to define a multitude of parameters which have to obey large number of rules arising from physics and technical constraints. Since this is hard to automate as long as the dependencies are not known sufficiently, the W7-X CoDaC team decided to implement an editor following a constructive approach: starting from an established experiment program the user is able to modify parts of it – thus complying the usual workflow of experimenters.Already the very first implementation has been deployed at the W7-X CoDaC prototype, the WEGA stellarator. Driven by agile programming principles the weighting of the requirements has been influenced by the editor usage in the daily experiment routine, thus ensuring client-oriented development steps and short release cycles. At present, a stable program editor implementation with graphical preview, immediate feedback on user actions and instantaneous warnings about incorrect settings is under continuous operation at the CoDaC prototype. It has potential to improve together with growing knowledge about the physical and technical constraints. The experiences gained give certainty that the editor is suitable for future use during the start-up phase and the first years of W7-X operation.     

Effects of Flicker in a Distribution Grid with High PV Penetration

The quantity of installed PV （photovoltaic） systems in the German distribution grid is still increasing. In some areas, the installed PV capacity exceeds 5 kW per HC （house connection）. Therefore, the load flow changes its characteristics and leads to new requirements for the grid. In some areas, the power feedback is higher than the delivery and the installed PV capacity becomes the decisive factor for grid planning. This paper discusses the impact of PV systems on the flicker level. The focus hereby is on the correlation among the flicker level, the grid voltage and the meteorological parameters. Different approaches to investigate if there is an influence of PV systems on the maximum flicker are taken into account. Furthermore, an investigation if the normative limit is exceeded will be shown.     

Measuring ISP topologies with Rocketfuel

To date, realistic ISP topologies have not been accessible to the research community, leaving work that depends on topology on an uncertain footing. In this paper, we present new Internet mapping techniques that have enabled us to measure router-level ISP topologies. Our techniques reduce the number of required traces compared to a brute-force, all-to-all approach by three orders of magnitude without a significant loss in accuracy. They include the use of BGP routing tables to focus the measurements, the elimination of redundant measurements by exploiting properties of IP routing, better alias resolution, and the use of DNS to divide each map into POPs and backbone. We collect maps from ten diverse ISPs using our techniques, and find that our maps are substantially more complete than those of earlier Internet mapping efforts. We also report on properties of these maps, including the size of POPs, distribution of router outdegree, and the interdomain peering structure. As part of this work, we release our maps to the community.     

Involvement of bristle coat structures in surface membrane formations and membrane interactions during coenocytotomic cleavage in caps of Acetabularia mediterranea

In the multinucleate cap rays of the green alga Acetabularia mediterranea the cell surface increases dramatically within a short time period during the final stages of coenocytotomic cleavage. In early stages of cyst formation the cytoplast is traversed by numerous large and prolate cleavage vesicles which are characterized by typical columellar or spinous coat structures. The cleavage vesicles are closely associated with the surface of plastids and, to a lesser degree, of mitochondria. This intimate association seems to be mediated by regularly spaced, densely stained intermembranous cross-bridge structures and is maintained throughout cleavage. These cleavage vesicles contain a finely fibrillar material structurally similar to the hyaline layer of mucilage that fills the space between the plasma membrane and cell wall. They line up with invaginations of the plasmalemma and vacuole membranes and, together with smaller vesicles interspersed, constitute preformed "perforation lines" for the final separation of the coenoblast portions. Equidistantly spaced plaques of attachment of such vesicles with surface membrane are described. We hypothesize (a) that the cleavage vesicle membrane is the immediate precursor to the new postcoenocytotomic surface membrane, (b) that the cleavage vesicle coat structures are integrated into the subsurface coat of the plasma membrane, (c) that growth of the laterally attached cleavage vesicles by intussusception of small fuzzy-coated vesicles is confined to their "free ends," (d) that the intermembranous cross-bridge elements are related to bristle coat structures and play a role in the establishment of the cleavage lines, and (e) that the coenocytotomic cleavage process is organized so that adjacent plastids are separated in a way that guarantees the inclusion of several plastids in each cyst.