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81.
J Suzuki M Isobe S Yamazaki S Horie Y Okubo M Sekiguchi 《Canadian Metallurgical Quarterly》1998,40(2):307-313
BACKGROUND & AIMS: Interleukin 12 (IL-12) is a heterodimeric, macrophage-derived cytokine that is elevated in Crohn's disease (CD). Epstein-Barr virus-induced gene 3 (EBI3) is a recently characterized human glycoprotein that is homologous to the 40-kilodalton chain of IL-12 and forms a heterodimer with the 35-kilodalton chain of IL-12. We investigated the expression of EBI3 in colonic mucosa of normal control subjects, patients with ulcerative colitis (UC), and patients with CD. METHODS: Colonic tissue was analyzed for messenger RNA (mRNA) expression by quantitative polymerase chain reaction and for protein expression by immunohistology and Western blotting. RESULTS: EBI3 mRNA was present in intestinal biopsy specimens from healthy subjects and patients with CD but was elevated only in active UC. EBI3 levels in UC specimens correlated with histological scores of activity and T-cell infiltration. EBI3-positive cells that had a shape consistent with that of macrophages were identified in the lamina propria, and protein was detected by Western blotting. CONCLUSIONS: EBI3 is a novel IL-12-related cytokine that is expressed by macrophage-like cells in normal intestine and CD and has enhanced expression in active UC but not in active CD. 相似文献
82.
A mar-resistant coating system was obtained by screening combinations of silicone and vinyl compounds. It was found that binary systems, such as the γ-glycidoxypropyltrimethoxysilane–glycidyl methacrylate system, were excellent not only in mar resistance but also in adhesion to base resin polymers. Haze values of these coatings, after the sand-falling test, reached less than 10%. The coating process consisted of three steps: the preparation of prepolymer, the coating to plastic surface, and the curing of the coating by heating. It was found that the prepolymerization step could be performed by irradiation very conveniently; the control of viscosity for coating application and thickness control could be possible without any gel formation. These coatings were also good in weather resistance due perhaps to the good adhesion to base resin and could be applicable to plastic spectacles, glazing materials, and a variety of other products. 相似文献
83.
The behavior of polycations as flocculants for kaolinite was examined by means of turbidity measurement, with the use of the following four kinds of cationic polysulfones, with molecular weights ranging from 14,000 to 330,000; diallyldimethylammonium chloride SO2 copolymer [P(DADMAmCl? SO2)], diallyldiethylammonium chloride–SO2 copolymer [P(DADEAmCl? SO2)], diallylmethylamine hydrochloride–SO2 copolymer [P(DAMA? HCl? SO2)], diallylamine hydrochloride–SO2 copolymer [P(DAAHCl? SO2)]. The effect of the degree of polymerization on the flocculation was remarkable at low molecular weight range. The flocculation value, which is defined as the quantity of the polycation required to obtain 50% transparency at 660 mμ of the supernatant fluid of 2% kaolinite suspension, was inversely proportional to the degree of polymerization to the 0.734 power in the case of P(DADMAmCl? SO2). This can be understood as the extension of Schulze-Hardy's law. The four different kinds of polysulfones having a similar molecular weight show almost the same capacity for flocculation in acidic or neutral solution. In alkaline solution, however, P(DAMAHCl? SO2) and P(DAA? HCl? SO2) are less effective and have higher flocculation values than P(DADMAmCl? SO2) and P(DADEAmCl? SO2), which are classified as polyquaternary ammonium chlorides. Moreover the difference increases with increasing pH. This may be attributable to the difference of the dissociability of the polycation. The degree of dissociation of P(DAMA? HCl? SO2) or P(DAA? HCl? SO2) decreases with increasing pH and more additive is required to neutralize negative charges on kaolinite. On the other hand, P(DADMAmCl? SO2) and P(DADEAmCl? SO2) are almost completely dissociated and are good flocculants over a wide range of pH. 相似文献
84.
Matsunaga S Ohshio K Harada E Fujiwara S Uchiyama S Fukui K 《Journal of Bioscience and Bioengineering》2004,98(5):384-386
We applied fluorescent microscopy to monitor the damage of DNA upon exposure to gamma radiation. Our developed dosimetry demonstrated that the number of breaks in DNA is proportional to the dose of the irradiation but is not dependent on dose rate of the irradiation and the GC content of DNA. 相似文献
85.
Mitsuhiro Horade Sommawan Khumpuang Kazuya Fujioka Susumu Sugiyama 《Microsystem Technologies》2007,13(3-4):215-219
We have investigated and report in this paper the factors influencing the deformation caused by the dependence between the
absorbed X-ray energy on the resist and the shape of the absorber on the X-ray mask. Based on the measurement of errors that
occurred during the transferring process between the 2-D shape of mask pattern and the resulting wall of the fabricated 3-D
structure, we have developed newly useful graphical data on the absorbed X-ray energy, dosage, and shape of a microstructure.
As a result, it is being reported as a method for compensation for the deformed shape after the fabrication of a quadruplets-microneedle.
We have considered a number of factors affecting the deformation and finally realized that the effect of a dose–depth nonlinear
curve is the most possible cause. Without the compensation of the mask design, we could observe the deformed shapes of the
sloped sidewall on the exposed structures. Polymethylmethacrylate microneedle structures fabricated by X-ray lithography with
an additional plane-pattern to cross-section transfers technique are directly influenced by the absorber on the X-ray mask
pattern. The sidewall of the microneedle was improved by changing the mask pattern from a double right-triangular pattern
to a double semi-circular pattern, modeled by comparing the results from a mask-pattern and the actual structure. 相似文献
86.
Large-sized β-FeSi2 substrates were successfully prepared for the first time from the silicide bulk crystal grown by the molten salt method. The structural, electrical and optical properties of the as-grown β-FeSi2 bulk crystals were also investigated. The crystal is single phase β-FeSi2, and polycrystalline with no preferable growth crystallographic orientations. It was also determined that the β-FeSi2 shows a p-type conduction, and the hole concentration and the Hall mobility at room temperature were about 1017 cm− 3 and 10 cm2/Vs, respectively. In addition, the PL emission around 0.8 eV was realized from the β-FeSi2 bulk crystal. This simple vacuum-free growth technique of β-FeSi2 and the large-sized substrate preparation procedure encourage us to develop future silicide-based electronics. 相似文献
87.
Kunihiro Suzuki Yuji Kataoka Susumu Nagayama Charles W. Magee Temel H. Buyuklimanli Tsutomu Nagayama 《Electron Devices, IEEE Transactions on》2007,54(2):262-271
We evaluated the redistribution profiles of ion-implanted impurities during solid-phase epitaxy using Rutherford backscattering spectrometry (RBS). RBS data revealed that the As concentration changes only near the moving amorphous/crystal interface. We derived an analytical model for the redistribution profiles using a segregation coefficient m between amorphous and crystalline Si, introduced a parameter of reaction length l that is the distance where impurities were exchanged, and obtained good agreement with experimental data with an m value of 3 and an l value of 1 nm for As. Furthermore, we applied our model to P and B redistribution profiles and obtained good agreement with corresponding m value of 4 and l value of 1 nm for P and m value of 0.3 and l value of 1 nm for B 相似文献
88.
Kojima H. Kinoshita O. Hayakawa N. Endo F. Okubo H. Yoshida M. Ogawa T. 《Dielectrics and Electrical Insulation, IEEE Transactions on》2007,14(6):1492-1497
From the viewpoint of mitigating global warming by SF6 gas, this paper discusses breakdown (BD) characteristics of different electronegative gas mixtures with N2O gas as SF6 gas substitutes for quasi-uniform electric field under lightning impulse voltage applications. Experimental results revealed the positive synergism in breakdown strength of binary N2O / CO2 and ternary N2O / CO2 / O2 gas mixtures, respectively. Furthermore, N2 gas as a retardant gas was also mixed with the electronegative gas mixtures in order to reduce the electron energy into the effective levels of electron attachment ability by the electronegative gas mixtures. As the result, ternary N2O / CO2 / N2 and quaternary N2O / CO2 / O2 / N2 gas mixtures could exhibit the significant synergistic effect in breakdown strength. The optimum mixture rate of quaternary N2O / CO2 / O2 / N2 gas mixtures was consistent with that estimated by assuming the independent contribution of component gases to the improvement of impulse BD characteristics. 相似文献
89.
Saijo Takashige Koike Shigeyoshi Tadakuma Susumu 《Industry Applications, IEEE Transactions on》1981,(5):533-543
Maglev vehicle ML-500 in Japan attained a speed of 517 km/h on December 21, 1979. The linear synchronous motor (LSM) drive cycloconverter fabricated and submitted to the track test has a capacity of approximately 12 000 kVA in a continuously variable frequency range of 0-34 Hz with a sinusoidal current waveform. The current can be arbitrarily controlled in a range of 200-1300 A. Despite the rigorous power conversion and control, excellent current control characteristics were obtained: less than 4 percent in deviation of current peak value, about 4 ° in leading phase deviation and approximately 1.2 ms in zero current interval. Some observations about the LSM driving system are made, and an outline of the design and the data obtained from the super-high-speed running tests on Miyazaki test track are given. 相似文献
90.
This paper describes the fabrication of poly(methyl methacrylate) (PMMA) microstructures with three-dimensional (3-D) sloped sidewalls using synchrotron-radiated (SR) deep X-ray lithography (DXRL). Here, the developer temperature was varied to produce variations in the inclination angle of the sloped sidewalls. We found that the PMMA sidewall inclination angle and height were controlled by the dosage, development time, and development temperature. When the development temperature was low, the inclination angle was nearly 0°, regardless of dosage amounts or exposure time. When the development temperature was high, microstructures with sloped sidewalls were fabricated; as the dosage amount and development time increased, the inclination angle increased. The ability to control the PMMA sidewall inclination angle suggests the application of this technique to microstructure fabrication technologies, such as 3-D microelectromechanical system (MEMS) device components, in which the inclination angle becomes the draft angle for moulding processes. 相似文献