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Honey and its Phytochemicals: Plausible Agents in Combating Colon Cancer through its Diversified Actions
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Balagowtham N. Acchutharaman K. R. Santhosh N. Pandian Muthu Senthil Ramasamy P. 《Journal of Materials Science: Materials in Electronics》2022,33(27):21531-21545
Journal of Materials Science: Materials in Electronics - The remarkable performance of organometallic lead halide perovskites in solar cell technology has drawn attention due to their intriguing... 相似文献
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Quantitative Detection of Nucleoside Analogues by Multi‐enzyme Biosensors using Time‐Resolved Kinetic Measurements
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Fast, simple and cost‐effective methods for detecting and quantifying pharmaceutical agents in patients are highly sought after to replace equipment and labor‐intensive analytical procedures. The development of new diagnostic technology including portable detection devices also enables point‐of‐care by non‐specialists in resource‐limited environments. We have focused on the detection and dose monitoring of nucleoside analogues used in viral and cancer therapies. Using deoxyribonucleoside kinases (dNKs) as biosensors, our chemometric model compares observed time‐resolved kinetics of unknown analytes to known substrate interactions across multiple enzymes. The resulting dataset can simultaneously identify and quantify multiple nucleosides and nucleoside analogues in complex sample mixtures. 相似文献
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The toxicity of phosphine, three alkyl halide fumigants (ethylene dibromide, methyl bromide and methyl iodide), carbon dioxide, mixtures of phosphine + alkyl halide fumigants, and phosphine + carbon dioxide, to 1-, 2-, and 3-day-old eggs of Tribolium castaneum Herbst was studied. Combinations of phosphine and alkyl halide fumigants showed antagonism as evidenced by their joint action ratios at the LD90 (< 1). The mortality data indicated that mixtures of phosphine and carbon dioxide were more effective than either alone. At LD50, the order of toxicity of the individual fumigants for a 24 hr exposure and on a weight basis (mg fumigant/litre of air) was: phosphine > methyl iodide > ethylene dibromide > methyl bromide. A decline in susceptibility of eggs with age for methyl bromide and ethylene dibromide and a peak tolerance at 2 days for carbon dioxide were noted. 相似文献