Study on phase behavior–impact strength relationship of unsaturated polyester/polyurethane hybrid polymer network

The phase behavior of a hybrid polymer network (HPN) composed of poly[(propylene glycol maleate)-co-(propylene glycol phthalate)] crosslinked with styrene and polyester–urethane crosslinked with methylene-bis-ortho-chloroaniline was examined. The correlation between phase separation and impact strength of the HPNs is discussed. The composition of HPNs has an effect on their properties.     

Reasoning about non-immediate triggers in biological networks

Modeling molecular interactions in signalling networks is important from various perspectives such as predicting side effects of drugs, explaining unusual cellular behavior and drug and therapy design. Various formal languages have been proposed for representing and reasoning about molecular interactions. The interactions are modeled as triggered events in most of the approaches. The triggering of events is assumed to be immediate: once an interaction is triggered, it should occur immediately. Although working well for engineering systems, this assumption poses a serious problem in modeling biological systems. Our knowledge about biological systems is inherently incomplete, thus molecular interactions are constantly elaborated and refined at different granularity of abstraction. The model of immediate triggers can not consistently deal with this refinement. In this paper we propose an action language to address this problem. We show that the language allows for refinements of biological knowledge, although at a higher cost in terms of complexity.      

Accuracy of asthma treatment in schoolchildren in NSW, Australia

Insufficient use of anti-inflammatory drugs, such as inhaled corticosteroids and cromoglycate, may contribute to the disease burden associated with asthma. Conversely, aggressive treatment of mild disease may result in avoidable costs and/or adverse drug effects. The aim of this study was to determine the relationship between asthma severity and inhaled corticosteroid/cromoglycate use in a large (n=4,909) random sample of children, aged 8-11 yrs, in NSW, Australia. Asthma and its treatment were assessed by questionnaire responses. Asthma, defined as diagnosis plus current wheeze, was present in 901 children (18% of the sample), of whom 225 (5%) had moderate asthma, defined as asthma plus additional symptoms (sleep disturbance), utilization (hospital, casualty), or disability (reduced activity, school absence). Use of inhaled corticosteroid/cromoglycate was reported by 636 children (13% of the sample). Determinants of use included: asthma diagnosis, current wheeze, and troublesome dry nocturnal cough. There was also a strong relationship between anti-inflammatory treatment and a multicomponent asthma severity score constructed for each child. Inhaled corticosteroids and/or cromoglycate were used by 56% of the children with asthma (24% daily) and by 76% of children with moderate asthma (42% daily). Undertreatment, defined as less than daily inhaled corticosteroids/cromoglycate in moderate asthma, was identified in 130 children (14% of those with asthma or 3% of the sample). Conversely, apparently aggressive treatment, defined as inhaled corticosteroid/cromoglycate use in children with persistent minimal symptoms (asthma severity score of less than 3) was identified in 101 children (2% of the sample). Although there were significant differences between regions in the choice of anti-inflammatory drugs and in the prevalence both of undertreatment and apparently aggressive treatment, there was no clear relationship to regional utilization of emergency and hospital services for asthma. Nevertheless, the frequency of undertreatment suggests an opportunity to reduce asthma morbidity by more consistent application of current therapeutic guidelines.     

Low phase noise millimeter-wave frequency sources using InP-basedHBT MMIC technology

A family of millimeter-wave sources based on InP heterojunction bipolar transistor (HBT) monolithic microwave/millimeter-wave integrated circuit (MMIC) technology has been developed. These sources include 40-GHz, 46-GHz, 62-GHz MMIC fundamental mode oscillators, and a 95-GHz frequency source module using a 23.8-GHz InP HBT MMIC dielectric resonator oscillator (DRO) in conjunction with a GaAs-based high electron mobility transistor (HEMT) MMIC frequency quadrupler and W-band output amplifiers. Good phase noise performance was achieved due to the low 1/f noise of the InP-based HBT devices. To our knowledge, this is the first demonstration of millimeter-wave sources using InP-based HBT MMIC's     

Penicillin vs. erythromycin in the treatment of diphtheria

PURPOSE: To review the University of Florida experience in treating ependymomas, analyze prognostic factors, and provide treatment recommendations. METHODS AND MATERIALS: Forty-one patients with ependymoma and no metastases outside the central nervous system received postoperative radiotherapy with curative intent between 1966 and 1989. Ten patients had supratentorial lesions, 22 had infratentorial lesions, and 9 had spinal cord lesions. All patients had surgery (stereotactic biopsy, subtotal resection, or gross total resection). Most patients with high-grade lesions received radiotherapy to the craniospinal axis. Low-grade intracranial lesions received more limited treatment. Spinal cord lesions were treated using either partial spine or whole spine fields. RESULTS: Of 32 intracranial tumors, 21 recurred, all at the primary site; no spinal cord tumors recurred. Overall 10-year survival rates were 51% (absolute) and 46% (relapse-free); by tumor site: spinal cord, 100%; infratentorial, 45%; supratentorial, 20% (p = 0.002). On multivariate analysis, tumor site was the only factor that influenced absolute survival (p = 0.0004); other factors evaluated included grade, gender, age, duration of symptoms, resection extent, primary tumor dose, treatment field extent, surgery-to-radiotherapy interval, and days under radiotherapy treatment. CONCLUSIONS: Patients with supratentorial or infratentorial tumors receive irradiation, regardless of grade. Craniospinal-axis fields are used when spinal seeding is radiographically or pathologically evident. Spinal cord tumors are treated using localized fields to the primary site if not completely resected. Failure to control disease at the primary site remains the main impediment to cure.     

基于MultiGen Creator/Vega的校园虚拟现实研究

VR与GIS相结合是VR技术的一个非常重要的应用,是实现＂数字地球＂、＂数字城市＂、＂数字区域＂等的关键技术之一。以武汉大学信息学部教学区为研究区域,利用教学区的航空影像、数字化地图、实测数据以及区内建筑物的数字影像,在MultiGen Creator/Vega软件平台上建立该区域的虚拟现实场景,实现三维模型漫游。并将此场景用于GIS,实现了GIS属性查询功能。     

基于模型修正技术的模拟集成电路几何规划优化方法

为了兼顾模拟集成电路设计优化的求解精度和计算效率,提出一种基于正项式模型修正技术的几何规划优化方法.首先将模拟集成电路的设计目标与约束简化为正项式模型,然后在采用几何规划方法迭代优化的过程中利用晶体管级SPICE仿真不断修正这一正项式模型.实例表明,与传统基于公式的优化方法和基于仿真的优化方法相比,该方法能够在尽量保证计算效率和全局最优解的前提下使优化精度满足晶体管级SPICE仿真的要求.     

改进的门单元多输入跳变电流源模型

电压信号的非线性问题和多输入跳变现象给时序分析带来了严重挑战.为更好地解决此问题,文中设计电路对门单元输入端和内部节点间的密勒电容进行了验证,从器件结构上分析了其来源,并通过引入该电容改进了已有多输入跳变电流源模型,以获得更高的模型精度;同时将二输入门单元模型扩展到多输入门单元,并详述了建模方法.多种门单元上的数值实验结果表明,与已有模型相比,在可接受的时间开销内,文中模型能够显著地提高门单元时延和输出波形的仿真精度.     

“三位一体”数字校园的设计与实现

介绍了集＂日常管理＂、＂水平评估＂、＂决策规划＂三位于一体的数字校园设计方案。通过规范基础数据,采用ESB整合各业务子系统,解决＂信息孤岛＂问题,并为状态数据采集提供便利。利用BI软件进行数据挖据,为管理者进行科学规划和决策提供数据支持。系统采用单点登录,个性化的门户展现满足了各类用户对资源和服务的需求。     

青藏高原东南部径流特征的空间规律及控制因子研究

采用青藏高原东南部的水文气象资料,对比分析了该地区23个(区间)流域的年径流深、集中度与集中期、基流系数、退水系数等径流特征及其空间分布规律,并进一步研究了这些径流特征的控制因子。结果表明:该地区径流特征的空间分布规律为年径流深从东南(700~1 300 mm)向西北(<400 mm)递减,而集中度则呈相反的空间格局(从<0.44增加到>0.59);退水系数及基流系数,在低海拔地区随高程增大而增大(分别为0.55~0.69、0.51~0.73),但在高海拔地区则随高程增大而减小(0.74~0.42、0.79~0.63)。本研究发现,青藏东南径流特征空间规律的控制因子,具有显著的区域分异:在低海拔流域(平均高程<3 000 m),降水是径流特征的主要影响因子;而在高海拔流域(平均高程>3 000 m),仅径流深和集中度受降水控制,其他特征则主要受温度、冻土、地形等条件的共同影响。可见,由于青藏高原东南部降水和冻土对气候变化敏感,该地区水资源时空分布格局将面临很大的不确定性,对此应予以充分重视。