Lithium containing silazanes as precursors for SiCN:Li ceramics—A potential material for electrochemical applications

Lithium containing silicon carbonitride ceramics (SiCN:Li) were synthesized via precursor-to-ceramic-transformation of Li-containing (poly)silazanes. The precursors were obtained by lithiation of the model compound 2,4,6-trimethyl-2,4,6-trivinylcyclotrisilazane and of a commercial poly(organosilazane) VL20^® with n-butyllithium in different molar ratios. According to Raman spectroscopic measurements, lithiation takes place at the NH groups of the molecular organosilazane structure. If the amount of n-BuLi exceeds the stoichiometric amount of NH groups, addition of n-BuLi at the vinyl groups (attached as substituents at the Si atoms of the silazane) occurs. Thermal analysis coupled with in situ mass spectrometry evidenced the loss of methane and hydrogen as the main gaseous by-products formed during the precursor-to-ceramic-transformation. The ceramization process is completed at 1100 °C in argon and yielded Li-containing silicon carbonitride, SiCN:Li. X-ray powder diffraction revealed that the resulting SiCN:Li ceramics were basically amorphous and contained LiSi₂N₃ as a crystalline phase with increasing amount of Li. Possible applications of the new SiCN:Li ceramics are seen in the field of Li-ion batteries as alternative anode or solid electrolyte material.     

Selective Isolation of Trypsin Inhibitor and Lectin from Soybean Whey by Chitosan/Tripolyphosphate/Genipin Co-Crosslinked Beads

Selective isolation of Kunitz trypsin inhibitor (KTI) and lectin from soybean whey solutions by different types of chitosan beads was investigated. The chitosan beads were co-crosslinked with tripolyphosphate/genipin in solutions at pH 5, 7 or 9 (CB5, CB7, CB9). The maximum adsorption ratios of chitosan beads to KTI and lectin were observed at pH 4.4 and 5.4, respectively; highly selective separation was also demonstrated at these pHs. The adsorption ratios increased with temperature, rising between 5 and 25 °C. CB9 produced the best adsorption ratio, followed by CB7 then CB5. The critical interaction governing absorption of chitosan beads to KTI and lectin could be hydrogen bonding. At pH 9, KTI and lectin desorbed efficiently from CB7 with desorption ratios of 80.9% and 81.4%, respectively. The desorption was most likely caused predominantly by electrostatic repulsion. KTI and lectin can effectively be selectively isolated from soybean whey using this novel separation technique.     

Flow fields around an intruder immersed in a 2D dense granular layer

We investigated the granular flows around a cylindrical intruder immersed in a two dimensional disordered granular medium for initial packing fractions close to but below the jamming transition. We observed a gradual transition in the flow behavior during the penetration of the intruder within the granular medium. The average longitudinal displacement field induced by the intruder penetration is characterized by a long-range decay in the first stage of motion. However the decay becomes exponential at more advanced stages with more developed recirculation of grains around the intruder. This transition towards a localization of the average flow is associated with the gradual compression of the granular medium in front of the intruder and with the onset of recirculations, in relation with the dynamics of the cavity that forms behind the intruder.     

Electrochemically Stimulated Release from Liposomes Embedded in a Polyelectrolyte Multilayer

Triggered release of an entrapped dye from vesicles embedded in a polyelectrolyte multilayer (PEM), as a consequence of the electrochemically induced local pH change in the vicinity of the electrode, is reported. The PEM was deposited on an indium tin oxide (ITO) electrode wherein lipid vesicles filled with a fluorescent dye were embedded. The use of vesicles with a strong negative charge and the polyelectrolyte species of the PEM matrix with a polycation as topmost layer enabled the generation of a stable layer of liposomes in the PEM.     

Knowledge-based parametric tools for concrete masonry walls: Conceptual design and preliminary structural analysis

The paper explores the potential uses of parametric modeling to embed construction and structural design knowledge in the form of generative rules and feedback rule-checking functions. The goal of the research reported here is to relate knowledge regarding constructive and structural principles during conceptual design in order to improve early decision-making. For that purpose we have developed a series of functions to guide conceptual design exploration by providing timely evaluation of design alternatives. The research focuses on load-bearing concrete masonry walls, and on basic requirements for doubly curved walls as a design case study. The research extends the Building Object Behavior methodology developed by Lee and others to elucidate, translate and implement design expertise into parametric rules and behaviors. The paper introduces the methodology in the context of a prototype modeling tool for early-stage design of concrete masonry walls and discusses the implications of a parametric modeling approach for conceptual design and collaboration.     

Late pulmonary impairment following allogeneic bone marrow transplantation

The pulmonary function of 88 consecutive leukemic patients who had undergone allogeneic bone marrow transplantation (BMT) was studied beforehand, at 3 months, at 6 months, and annually thereafter until 5 years after grafting. The parameters for function which are indicative for obstructive and restrictive lung disease deteriorated in all patient groups during the first 3 to 6 months after BMT but partially recovered within one year. Long-term decline in lung function was similar in all patient groups, and neither the onset nor the magnitude of pulmonary dysfunction was related to the occurrence of pulmonary impairment within 6 months after grafting. Multivariate analysis was then employed to assess predictors for long-term pulmonary disease. Despite the obvious effect of chronic graft versus host disease on the course of lung function, it was in itself not a significant predictor of long-term pulmonary outcome. Rather, the conditioning regimen turned out to be indicative; compared with busulfan, fractionated total body irradiation was demonstrated to be clearly superior with a lower incidence of both restrictive and obstructive long-term lung impairment. Our data indicate a previously unknown long-term side effect of busulfan conditioning.     

CMGC gasket applied to a large reactor vessel

The satisfactory sealing of large reactor vessel flanges in petrochemical plant is a significant problem. It is necessary to accommodate relative flange movement of large pressure vessels and provide a system where adequate bolting can be applied. The leakage from a large flange can be a major contributor to plant emissions. Here a corrugated metal graphite covered gasket has been used to seal a flange 20 feet (6 m) in diameter on a high-temperature (450°C) reactor vessel. This has resulted in a significant reduction in emissions and plant maintenance. This feature is based on the submission by the winning team in the Fluid Sealing Association's 2003 Environmental Achievement Awards.     

Topography of ribosomal proteins: reconsideration of of protein map of small ribosomal subunit

Exposure of proteins on the surface of the small (30S) ribosomal subunit of Escherichia coli was studied by the hot tritium bombardment technique. Eight of 21 proteins of the 30 S subunit (S3, S8, S10, S12, S15, S16, S17, and S19) had virtually no groups exposed on the surface of the particle, i.e., they were mainly hidden inside. Seven proteins (S1, S4, S5, S7, S18, S20, and S21) were all well exposed on the surface of the particle, thus being outside proteins. The remaining proteins (S2, S6, S9 and/or S11, S13, and S14) were partially exposed. On the basis of these results a reconcilement of the three-dimensional protein map of the small ribosomal subunit has been done and corrected model is proposed.