Development of quantitative structure-activity relationships for explanatory modeling of fast reacting (meth)acrylate monomers bearing novel functionality

The photoinitiated polymerization of (meth)acrylate monomers bearing novel carbamate functionality exhibits significantly greater reaction rate when compared to more traditional acrylate monomers undergoing similar polymerization. This unusually fast reactivity has been the subject of much investigation. In order to suggest an explanatory mechanism for the enhanced polymerization rates we have conducted quantitative structure-activity relationship investigations of these novel monomers. These studies have resulted in statistically sound models with coefficients of multiple determination of R(2)>0.93. Principal component and k nearest neighbor similarity analysis were also conducted on the multiple regression models. These results are discussed in light of published experimental investigations of the photopolymerization reactivity of the novel monomers.     

Interface with angels: the future of VIR and AR interfaces

Although real guardian angels aren't easy to get hold of, some of the computer technology needed for such a personal assistant is already available. Other parts exist in the form of research prototypes, but some technological breakthroughs are necessary before we can realize their potential, let alone integrate into our daily routines. Future VR and AR interfaces won't necessarily try to provide a perfect imitation of reality but instead will adapt their display mechanisms to their users' individual requirements. The emergence of these interfaces won't rely on a single technology but will depend on the advances in many areas, including computer graphics, display technology, tracking and recognition devices, natural and intuitive interactions, 3D interaction techniques, mobile and ubiquitous computing, intelligent agents, and conversational user interfaces, to name a few. The guardian angel scenario exemplifies how future developments in AR and VR user interfaces might change the way we interact with computers. Although this example is just one of several plausible scenarios, it demonstrates that AR and VP, in combination with user-centered design of their post-WIMP interfaces, can provide increased access, convenience, usability, and efficiency     

Development of a Virtual Reality Structural Analysis System

This paper discusses the development of virtual structural analysis program (VSAP). This is a virtual environment (VE) based structural analysis system developed through a collaborative effort between the School of Architecture + Design and the Department of Computer Science at Virginia Polytechnic Institute and State Univ. (Virginia Tech). The VSAP was developed by linking a visualization routine using the simple VE library and a structural analysis software, the PC-SAP4. Details of the design of four user interfaces for the VSAP are presented. These user interfaces are: the immersive pen and tablet interface, the desktop interface, the portable immersive interface, and the cave automatic VE immersive interface. Usability studies for each interface were conducted. Results of these studies indicated that the users of VSAP were highly satisfied with the experience. In addition, all the developed interfaces were found to be successful for their specific application.     

Mexitl: Multimedia in Executable Interval Temporal Logic

This paper explores a formalism for describing a wide class of multimedia document constraints, based on an interval temporal logic. We describe the requirements that arise from the multimedia documents application area, and we illustrate these requirements using several examples. Then we present the temporal logic formalism that we use. This logic extends existing interval temporal logic with a number of new features: actions, framing of actions, past operators, a projection-like operator called filter and a new handling of interval length. The notation is applied to the specification of the examples, and in particular a set of logical manipulations, providing feedback to an author, is presented. A model theory, logic and satisfaction relation are defined for the notation.     

Discriminative Stimulus, Reinforcing, Physical Dependence, and Antinociceptive Effects of Oxycodone in Mice, Rats, and Rhesus Monkeys.

Despite oxycodone's (4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one) history of clinical use and the attention it has received as a drug of abuse, few reports have documented its pharmacology's relevance to its abuse or its mechanism of action. The purposes of the present study were to further characterize the analgesic effects of oxycodone, its mechanism of action, and its effects in terms of its relevance to its abuse liability. The results indicate that oxycodone had potent antinociceptive effects in the mouse paraphenylquinone writhing, hot-plate, and tail-flick assays, in which it appeared to be acting as a μ-opioid receptor agonist. It generalized to the heroin discriminative stimulus and served as a positive reinforcer in rats and completely suppressed withdrawal signs in morphinedependent rhesus monkeys. These results suggest that the analgesic and abuse liability effects of oxycodone are likely mediated through μ-opioid receptors and provide the first laboratory report of its discriminative stimulus, reinforcing, and morphine cross-dependency effects. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effect of cellulosic sugar degradation products (furfural and hydroxymethyl furfural) on acetone–butanol–ethanol (ABE) fermentation using Clostridium beijerinckii P260

Studies were performed to identify chemical compounds present in wheat straw hydrolysate (WSH) that enhance acetone butanol ethanol (ABE) productivity. These compounds were identified as furfural and hydroxymethyl furfural (HMF). Control experiment resulted in the production of 21.38 g L^?1 ABE with a productivity of 0.30 g L^?1 h^?1. WSH contained 0.04–0.34 g L^?1 furfural and 0.12–0.88 g L^?1 HMF. Addition of furfural to the fermentation medium at a concentration of 0.50 g L^?1 resulted in a productivity of 0.88 g L^?1 h^?1 which is 293% of the productivity obtained in control experiments. Supplementation with 1.00 g L^?1 HMF into the fermentation medium produced 25.27 g L^?1 ABE with a productivity of 0.68 g L^?1 h^?1. A combination of furfural (0.50 g L^?1) and HMF (0.50 g L^?1) also enhanced ABE production and productivity when added to the fermentation medium. Both furfural and HMF enhanced specific productivity (233–308%) of ABE. In brief, WSH contained an adequate concentration of furfural and HMF that enhanced ABE productivity, specific productivity, and product concentration.     

Influence of Cr3+ on yellowish-green UC emission and energy transfer of Er3+/Cr3+/Yb3+ tri-doped zinc silicate glasses

In this paper, we study the influence of Cr³⁺ on yellowish-green upconversion (UC) emission and the energy transfer (ET) of Er³⁺/Cr³⁺/Yb³⁺ tri-doped in SiO₂–ZnO–Na₂O–La₂O₃ (SZNL) zinc silicate glasses under excitation of the 980 nm laser diode (LD). The influence of Cr³⁺ on enhancing the red UC emission of Er³⁺/Cr³⁺/Yb³⁺ tri-doped in SiO₂–ZnO–Na₂O–La₂O₃ zinc silicate glasses under the excitation of 980nm LD was also investigated. The ET processes between Yb³⁺, Cr^3+, and Er³⁺, together with the combination of Yb³⁺-Cr³⁺-Er³⁺, which led to the green UC emission intensity of Er³⁺/Cr³⁺/Yb³⁺ tri-doped in SiO₂–ZnO–Na₂O–La₂O₃ zinc silicate glasses bands centered at ~546 nm have been significantly enhanced. By increasing the concentration of Cr³⁺ from 0 up to 5 mol.%, we can locate the Commission Internationale de l'éclairage (CIE) 1931 (x; y) chromaticity coordinates for UC emissions of Er³⁺/Cr³⁺/Yb³⁺ tri-doped in the central position of the yellowish-green color region of CIE 1931 chromaticity diagram. Besides, the ET processes between the Yb³⁺, Cr³⁺, and Er³⁺ are also proposed and discussed.     

Categorically defined targets trigger spatiotemporal visual attention.

Transient attention to a visually salient cue enhances processing of a subsequent target in the same spatial location between 50 to 150 ms after cue onset (K. Nakayama & M. Mackeben, 1989). Do stimuli from a categorically defined target set, such as letters or digits, also generate transient attention? Participants reported digit targets among keyboard symbols in a changing array of 8 items. When 1 target preceded a second target in the same location at a stimulus onset asynchrony of 107 ms (but not 213 ms), the second target was reported more often than in a condition in which there was no leading target. When the 2 targets were at different locations, report of the second target was impaired. With both letters and digits as targets, the enhancement effect was shown not to be due to category priming. Critically, the attentional benefit was present whether or not participants reported the leading target. Transient attention, contingent attentional capture, popout, and Lag 1 sparing in the attentional blink may involve a common mechanism for orienting processing resources towards salient and task relevant stimuli. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Discussion of papers

This paper describes a bridge condition assessment model that is based upon the simplification of a computational technique called resolution identity of fuzzy sets. The proposed model utilizes a fuzzy weighted average to combine fuzzy bridge condition ratings. The procedure is based on the decomposition of fuzzy sets into non-fuzzy level-sets or intervals. The utility and effectiveness of this procedure are illustrated with an example of the bridge condition assessment problem.     

Unipolar Fatigue Behavior of BCTZ Lead‐Free Piezoelectric Ceramics

(Ba,Ca)(Ti,Zr)O₃ lead‐free piezoelectric ceramics have been considered to be one of the most potential lead‐free alternatives for PZT in the room‐temperature range. The stability of the piezoelectric performance during unipolar cycling is investigated in this study. It is found that the unipolar fatigue behavior is similar to soft PZT. Developments of bias field, offset polarization, asymmetry in strain, and dielectric hysteresis loops are observed during bipolar measurements. The changes are mainly contributed to the migration of charge carriers to the grain boundaries driven by the unscreened depolarization field. Redistribution of the accumulated charge carriers by bipolar electric cycling or thermal annealing can significantly recover the unipolar fatigued state. The unipolar strain response stabilized after 1000 cycles at 0.053% for an electric field of 0.6 kV/mm (d₃₃*= 883 pm/V), which is a good characteristic for actuator applications.