环氧树脂修补材料固化行为研究

采用差示扫描量热法（DSC）对自行研制的环氧胶黏剂进行了固化反应动力学研究,采用Kissinger微分法对DSC曲线进行处理,求得了体系的固化反应活化能,通过Crane方程得到反应级数为0.891,表明体系的固化反应是一个复杂反应,另外促进剂的加入加速固化反应并降低了反应的活化能;通过动力学数据的分析可知温度每升高10℃,反应速率提高约1倍。另外水工室外应用条件复杂,气温变化大,通过胶黏剂动力学参数与适用期数据的分析,提出了施工中材料适用期的确定方法。     

Oscillation Susceptibility Analysis along the Path of the Longitudinal Flight Equilibriums in ADMIRE Model

Our goal is the oscillation susceptibility analysis in the framework of a nonlinear mathematical model in the so-called ADMIRE or Aero Data Model in a Research Environment. First, we analyze the oscillation susceptibility along the path of the longitudinal flight equilibriums when the flight control system (FCS) is decoupled. After that, a similar analysis is undertaken in the case when the FCS is coupled. For decoupled FCS, it is shown that on the path of the longitudinal flight equilibriums there exists a saddle-node where stability is lost and fold bifurcation occurs. Maneuvers are simulated showing the effect of an instantaneous change of the elevator angle, and the evolution of the unstable equilibriums (due to the maneuvers) to the corresponding exponentially stable equilibriums. It is shown numerically that at the saddle-node oscillations occur when the elevator angle is less than the critical value and the start is from the saddle-node. More precisely, it is shown that if the plane state parameters coincide with the saddle-node coordinates and the elevator angle is changed instantaneously from the critical value to a value which is less than this value, then two of the state parameters (α,q) begin to oscillate with the same period and the third parameter (θ) increases, tending to infinity. Thus, the orbit of the system evolves spiraling. It is shown also, that if the elevator angle is reset, the plane returns to a stable equilibrium. Therefore, a soft or no catastrophic stability loss takes place. When the FCS is coupled, the plane for every value of the amplification factor has a unique equilibrium which is exponentially stable and attracts all the equilibriums which exist in decoupled case. In this case, there are no bifurcation points on the equilibrium path. The dependence of the equilibrium and of the relaxation period on the amplification factor value is found numerically. Finally, it is concluded that when the FCS is decoupled, then along the path of the longitudinal equilibriums oscillations can occur, but when the FCS is coupled and the pilot can modify (instantaneously) only the amplifier factor value, then the vehicle, defined by the considered numerical data, is not anymore susceptible to oscillation.     

Investigating Biomarkers for USH2A Retinopathy Using Multimodal Retinal Imaging

Pathogenic mutations in USH2A are a leading cause of visual loss secondary to non-syndromic or Usher syndrome-associated retinitis pigmentosa (RP). With an increasing number of RP-targeted clinical trials in progress, we sought to evaluate the photoreceptor topography underlying patterns of loss observed on clinical retinal imaging to guide surrogate endpoint selection in USH2A retinopathy. In this prospective cross-sectional study, twenty-five patients with molecularly confirmed USH2A-RP underwent fundus autofluorescence (FAF), spectral-domain optical coherence tomography (SD-OCT) and adaptive optics scanning laser ophthalmoscopy (AOSLO) retinal imaging. Analysis comprised measurement of FAF horizontal inner (IR) and outer (OR) hyperautofluorescent ring diameter; SD-OCT ellipsoid zone (EZ) and external limiting membrane (ELM) width, normalised EZ reflectance; AOSLO foveal cone density and intact macular photoreceptor mosaic (IMPM) diameter. Thirty-two eyes from 16 patients (mean age ± SD, 36.0 ± 14.2 years) with USH2A-associated Usher syndrome type 2 (n = 14) or non-syndromic RP (n = 2) met the inclusion criteria. Spatial alignment was observed between IR-EZ and OR-ELM diameters/widths (p < 0.001). The IMPM border occurred just lateral to EZ loss (p < 0.001), although sparser intact photoreceptor inner segments were detected until ELM disruption. EZ width and IR diameter displayed a biphasic relationship with cone density whereby slow cone loss occurred until retinal degeneration reached ~1350 μm from the fovea, beyond which greater reduction in cone density followed. Normalised EZ reflectance and cone density were significantly associated (p < 0.001). As the strongest correlate of cone density (p < 0.001) and best-corrected visual acuity (p < 0.001), EZ width is the most sensitive biomarker of structural and functional decline in USH2A retinopathy, rendering it a promising trial endpoint.     

Antidiabetic Drugs in the Treatment of Alzheimer’s Disease

The public health burden of type 2 diabetes mellitus and Alzheimer’s disease is steadily increasing worldwide, especially in the population of older adults. Epidemiological and clinical studies suggest a possible shared pathophysiology between the two diseases and an increased risk of AD in patients with type 2 diabetes mellitus. Therefore, in recent years, there has been a substantial interest in identifying the mechanisms of action of antidiabetic drugs and their potential use in Alzheimer’s disease. Human studies in patients with mild cognitive impairment and Alzheimer’s disease have shown that administration of some antidiabetic medications, such as intranasal insulin, metformin, incretins, and thiazolidinediones, can improve cognition and memory. This review aims to examine the latest evidence on antidiabetic medications as a potential candidate for the treatment of Alzheimer’s disease.     

同步采样时统卡的WMD驱动程序设计

WDM是Windows平台下新一代的驱动程序模型.本文介绍了用Numega DriverStudio开发WDM设备驱动程序的流程和步骤,简述了驱动程序的生成,调试和安装的方法.针对基于ISA总线的时统卡,详细介绍了WDM驱动程序的开发过程.     

一种新的XML数据编码方案

如何对XML文档进行高效的查询,特别是包含查询处理,越来越受到研究界的关注。一种好的XML文档树编码方案可以很好地支持在XML文档上进行包含查询。为了加快XML数据的处理,利用完全二叉树的特性,提出了一种新的编码方案BTC。与区间编码和前缀编码相比,该编码具有简单和长度短的优点,实践证明该编码是有效的。     

一种基于温差测量原理工作的集成型流量传感器􀀂

在比较已有的几种低流速流体的流速流量测量方法基础上,提出一种利用与流速相关温差的测量方案,并用芯片集成方法构成流量传感器加以验证,实验结果与理论预期基本相符.该传感器的主要优点是在低流量条件下具有高灵敏度.     

一种新型位移- 数字转换方法的研究

通过对感应同步器位移测量方法的研究，提出了一种以感应同步器为传感器，将软件与硬件有机结合的位移-数字转换新方法。该方法将位移测量功能合理分配，在硬件设计上采用功能强的大规模集成电路，简化系统结构；对于占用硬件资源多而软件上又易实现的功能则直接由软件实现。研究与应用结果表明：利用该方法所设计的宽度测控系统具有测量精度高、结构简单、适应性强等特点，对位移测控系统具有一定的推广价值。     

织机监控系统在企业内部网中的应用

针对现在纺织企业内部网使用的情况,设计了一个织机网络监控系统,其能够实时地监控大量的织机运行状态,及时地保存织机停车的相关信息,同时还可以将相关的织机产量保存于本地数据库中,方便用户进行查询.实现了织机的花形文件更新,大大提高了生产效率.     

基于RBF神经网络的传感器静态误差综合校正方法

以一受环境温度和电源波动影响的压力传感器为例,说明了具体实现方法和校正效果.并与采用BP神经网络进行误差校正的方法进行了比较.实验结果表明,采用RBF神经网络可以明显提高网络收敛速度,大大减小传感器静态误差,校正效果优于BP神经网络.