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排序方式: 共有1234条查询结果,搜索用时 15 毫秒
91.
Fabrizio Quadrini Loredana Santo Vincenzo Tagliaferri Federica Trovalusci 《Polymer Engineering and Science》2010,50(11):2079-2084
A new molding technique is proposed to directly mold small parts from thermoplastic pellets. A small molding machine was designed and fabricated: the mold consisted of a transparent glass and a metallic frame; an infrared (IR) lamp provided the heat for the pellet melting. Molding tests were carried out by using three commercial thermoplastics and two metallic molds. Molding time and IR lamp power were changed to extract a moldability window for each combination of material and metallic mold. In the best process conditions, a high quality of the samples was obtained in terms of mold filling and surface aesthetics. POLYM. ENG. SCI., 2010. © 2010 Society of Plastics Engineers 相似文献
92.
Eva Dreussi Erika Cecchin Jerry Polesel Vincenzo Canzonieri Marco Agostini Caterina Boso Claudio Belluco Angela Buonadonna Sara Lonardi Francesca Bergamo Sara Gagno Elena De Mattia Salvatore Pucciarelli Antonino De Paoli Giuseppe Toffoli 《International journal of molecular sciences》2016,17(9)
Background: Pathological complete response (pCR) to neoadjuvant chemoradiotherapy (CRT) in locally advanced rectal cancer (LARC) is still ascribed to a minority of patients. A pathway based-approach could highlight the predictive role of germline single nucleotide polymorphisms (SNPs). The primary aim of this study was to define new predictive biomarkers considering treatment specificities. Secondary aim was to determine new potential predictive biomarkers independent from radiotherapy (RT) dosage and cotreatment with oxaliplatin. Methods: Thirty germ-line SNPs in twenty-one genes were selected according to a pathway-based approach. Genetic analyses were performed on 280 LARC patients who underwent fluoropyrimidine-based CRT. The potential predictive role of these SNPs in determining pathological tumor response was tested in Group 1 (94 patients undergoing also oxaliplatin), Group 2 (73 patients treated with high RT dosage), Group 3 (113 patients treated with standard RT dosage), and in the pooled population (280 patients). Results: Nine new predictive biomarkers were identified in the three groups. The most promising one was rs3136228-MSH6 (p = 0.004) arising from Group 3. In the pooled population, rs1801133-MTHFR showed only a trend (p = 0.073). Conclusion: This exploratory study highlighted new potential predictive biomarkers of neoadjuvant CRT and underlined the importance to strictly define treatment peculiarities in pharmacogenetic analyses. 相似文献
93.
94.
Biogenic amines are frequently found in wine and other fermented food. We investigated the ability of 133 strains of lactic acid bacteria isolated from musts and wines of different origins to produce histamine, tyramine, and putrescine. We detected the genes responsible for encoding the corresponding amino acid decarboxylases through PCR assays using two primer sets for every gene: histidine decarboxylase (hdc), tyrosine decarboxylase (tdc), and ornithine decarboxylase (odc); these primers were taken from the literature or designed by us. Only one strain of Lactobacillus hilgardii was shown to possess the hdc gene, whereas four strains of Lactobacillus brevis had the tdc gene. None of the Oenococcus oeni strains, the main agents of malolactic fermentation, was a biogenic amine producer. All PCR amplicon band-positive results were confirmed by thin-layer chromatography and high-performance liquid chromatography analyses. 相似文献
95.
Perugini M Giammarino A Olivieri V Di Nardo W Amorena M 《Journal of food protection》2006,69(5):1144-1149
It is estimated that 90% of human exposure to persistent organic pollutants is through food, and fish and shellfish represent an important source of contamination for polychlorinated biphenyls (PCBs) and organochlorine insecticides. To evaluate the levels of seafood contamination coming from the central Adriatic Sea, Italy, a study involving several pools of shellfish, crustaceans, and fish was carried out. Several marine species were selected by their abundance, wide distribution, and common use in the Italian diet and sampled and analyzed during 2004. The concentration of total (sigma) PCBs exceeded that of total dichlorodiphenyltrichloroethanes (DDTs) in all samples. Atlantic mackerel showed the highest concentrations of PCBs, ranging from 514 to 1772 ng/g of fat weight, and DDTs, ranging from 52 to 656 ng/g of fat weight. The lowest concentrations of PCBs and DDTs were found in cephalopods and mussels. Despite this, to protect human health from these pollutants, legal limits have been established for fish and shellfish for DDTs but not PCBs. The most common representative PCB congeners, in all species, were PCB 153 and PCB 138; the most common DDT was p,p'-dichlorodiphenyldichloroethylene. 相似文献
96.
97.
Rahul Sasidharan Pillai Matteo Frasnelli Vincenzo M. Sglavo 《Ceramics International》2018,44(2):1328-1333
The present work focuses on the fabrication of βTCP (β-tricalcium phosphate) and HA/βTCP (hydroxyapatite/β-tricalcium phosphate) composite coatings by plasma spraying. The starting powders were produced via solid-state method using 2 wt% MgO to stabilize βTCP phase. The synthesized powders were preliminarily granulated to be used by the plasma spray process. Coatings obtained on titanium substrates are uniform and well adherent but due to the high temperature and cooling rate typical for plasma spraying process, βTCP phase is almost totally transformed into the α allotrope. Thermal treatment at 800 °C allows the reconversion of the phase αTCP→ βTCP. It is therefore possible to produce coatings with tuneable dissolution properties by selecting the proper initial powder mixture and the specific thermal treatment. 相似文献
98.
Andrea Petrella Valentina Petruzzelli Ezio Ranieri Vincenzo Catalucci 《Chemical Engineering Communications》2016,203(7):940-947
Selective sorption of lead, cadmium, and nickel ions on recycled waste porous glass beads was investigated. Single-metal equilibrations were carried out in demineralized water and ternary metal equilibrations were carried out in demi- and tap water. Freundlich isotherm gave a good correlation of the experimental data. Maximum metal retention (qmax) in single-ion solutions were 18.66 mg/gRPWG (0.090 mmol/gRPWG), 4.83 mg/gRPWG (0.043 mmol/gRPWG), 4.00 mg/gRPWG (0.068 mmol/gRPWG), respectively, for Pb+2, Cd+2, and Ni+2, and lower figures were in the case of ternary systems: 13.50 mg/gRPWG(0.065 mmol/gRPWG), 2.23 (0.020 mmol/gRPWG), 2.05 mg/gRPWG(0.034 mmol/gRPWG), respectively, for Pb+2, Cd+2, and Ni+2, with further drastic reduction in tap water. Metal exhausted beads were used as thermal insulators in cement mortars, minimizing their potential impact in the environment. 相似文献
99.
Indentation Determination of Fatigue Limits in Silicate Glasses 总被引:1,自引:0,他引:1
An experimental approach has been used to measure the threshold stress intensity factor ( K th ) for subcritical crack growth in brittle materials using indentation cracks. The data show that K th values existed in soda-lime-silica and soda-alumina-silica glasses that were tested in a neutral aqueous environment. For the former glass, tests also were performed in acidic and basic solutions. A threshold for subcritical crack growth was observed for acidic conditions but not for alkaline conditions. 相似文献
100.
Vincenzo M. Sglavo Paolo Bosetti Elena Trentini Michele Ceschini 《Journal of the American Ceramic Society》1999,82(8):2269-2272
A technique for precracking brittle materials is presented. This procedure, which is called the sandwiched-beam (SB) technique, allows the production of sharp through-thickness cracks with predetermined length in specimens with a rectangular section. A bar, in which an initial notch is produced by using a conventional saw, is inserted between two supporting beams and the sandwich assembly is loaded in three-point bending. Conditions can be defined that allow the stable propagation of a sharp flaw from the notch as the applied load is increased. Then, the cracked bar can be used to determine the fracture toughness. The SB technique is applied to different brittle materials, including soda-lime-silica glass, alumina, Si3 N4 , a SiC w -Si3 N4 composite, graphite, a Ti-Al intermetallic, and Carrara marble. 相似文献