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91.
    
This study presents a Laser Zone Melting method with potential for producing planar waveguides at large scale, based on the surface coupling of two chemically compatible glass layers which exhibit distinct indices of refraction. The method is based on a recent patent, particularly applicable to process glass and ceramics with low thermal shock resistance. Glass coatings containing 76.24% by weight PbO are thus here reported, as obtained by this method on commercial soda-lime planar glass substrates. Their higher indices of refraction (1.58 vs 1.52 for commercial soda-lime glass) result in attractive waveguiding potential, as demonstrated with measurements using focused light from a He-Ne laser beam. Scanning and transmission electron microscopy studies reveal excellent integration and compatibility between the observed coatings and substrates, where diffusion in the proximity of the interface was studied by EDS analysis. Crystalline phases have not been found within the coating, or within the substrate, as concluded from the absence of Bragg-peaks in XRD experiments.  相似文献   
92.
    
Prolonged sitting is a risk factor for several diseases and the prevalence of worksite-based interventions such as sit-to-stand workstations is increasing. Although their impact on sedentary behaviour has been regularly investigated, the effect of working in alternating body postures on cognitive performance is unclear. To address this uncertainty, 45 students participated in a two-arm, randomised controlled cross-over trial under laboratory conditions. Subjects executed validated cognitive tests (working speed, reaction time, concentration performance) either in sitting or alternating working postures on two separate days (ClinicalTrials.gov Identifier: NCT02863731). MANOVA results showed no significant difference in cognitive performance between trials executed in alternating, standing or sitting postures. Perceived workload did not differ between sitting and alternating days. Repeated measures ANOVA revealed significant learning effects regarding concentration performance and working speed for both days. These results suggest that working posture did not affect cognitive performance in the short term.

Practitioner Summary: Prior reports indicated health-related benefits based on alternated (sit/stand) body postures. Nevertheless, their effect on cognitive performance is unknown. This randomised controlled trial showed that working in alternating body postures did not influence reaction time, concentration performance, working speed or workload perception in the short term.  相似文献   

93.
    
This article outlines advances in molecular modeling and simulation using massively parallel high‐performance computers (HPC). In the SkaSim project, partners from the HPC community collaborated with users from science and industry. The aim was to optimize the prediction of thermodynamic property data in terms of efficiency, quality and reliability using HPC methods. In this context, various topics were dealt with: atomistic simulation of homogeneous gas bubble formation, surface tension of classical fluids and ionic liquids, multicriteria optimization of molecular models, the development of the molecular simulation codes ls1 mardyn and ms2, atomistic simulation of gas separation processes, molecular membrane structure generators, transport resistors and the evaluation of predictive property data models based on specific mixture types.  相似文献   
94.
    
Interrogation and control of cellular fate and function using optogenetics is providing revolutionary insights into biology. Optogenetic control of cells is achieved by coupling genetically encoded photoreceptors to cellular effectors and enables unprecedented spatiotemporal control of signaling processes. Here, a fast and reversibly switchable photoreceptor is used to tune the mechanical properties of polymer materials in a fully reversible, wavelength‐specific, and dose‐ and space‐controlled manner. By integrating engineered cyanobacterial phytochrome 1 into a poly(ethylene glycol) matrix, hydrogel materials responsive to light in the cell‐compatible red/far‐red spectrum are synthesized. These materials are applied to study in human mesenchymal stem cells how different mechanosignaling pathways respond to changing mechanical environments and to control the migration of primary immune cells in 3D. This optogenetics‐inspired matrix allows fundamental questions of how cells react to dynamic mechanical environments to be addressed. Further, remote control of such matrices can create new opportunities for tissue engineering or provide a basis for optically stimulated drug depots.  相似文献   
95.
    
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97.
Among the various possible ways of dealing with notch and crack situations, the scaled boundary finite element method [SBFEM, (Wolf and Song in Finite element modelling of unbounded structures. Wiley, Chichester, 1996; Wolf in The scaled boundary finite element method. Wiley, Chichester, 2003)] has been adopted in this work. This method has been proved to be versatile, much less time consuming than the finite element method and generates highly accurate numerical predictions in cases of structures with notches and cracks. The SBFEM gives the advantage of boundary element method by reducing one dimension in modelling the structures but the mathematical formulations are more related to conventional displacement based finite element method. This method requires a certain scalability of the given structure with respect to a point called similarity center. Like in the case of the boundary element method, the structure needs to be discretized only at the surface where standard displacement based isoparametric finite element formulations are adequate. Unlike in the boundary element method, however, no fundamental solution is required by the scaled boundary finite element method. The similarity or scalability of the method requires separation of coordinates such that in the radial direction (i.e. scaling direction) it yields simple differential equations that can be solved analytically. So this approach can be considered as a semi-analytical method. Several two-dimensional examples have been analysed for crack and notch situations that are well known cases in fracture mechanics. A number of three-dimensional cases have been considered for different crack configurations that yield high order of singularity. The results, according to the authors’ knowledge are up to now unpublished in the open literature. Parametric studies are conducted for structures with bi-material interfaces.  相似文献   
98.
The static fatigue of SiC-based fiber bundles and single fibers has been examined in previous papers, with emphasis placed on the analysis of the stress–rupture time data, and on the modelling of delayed failure from slow crack growth. The present paper investigates the oxidation of the fibers during static fatigue, at temperatures in the intermediate temperature range (500°–800°C). Two oxidation-induced phenomena have been evidenced: the formation of a thin silica film at the surface of fibers and the delayed failure of fiber bundles and single filaments. The stress–rupture time data are interpreted with respect to the chemical and structural characteristics of fibers, and to the oxide film growth rate. The structural analysis of the fibers was carried out using scanning electron microscopy and Auger electron spectroscopy. Delayed failure was found to result from slow crack propagation from surface defects, as a result of the consumption of the free carbon at grain boundaries and the local stresses induced by the SiC→SiO2 transformation at the crack tip. The respective contributions of these phenomena to static fatigue are discussed.  相似文献   
99.
    
High structure or so‐called conductive carbon blacks (CCBs) constitute the major family of conductive additives. They enable one to make polymers permanently conductive at “low” to “very low” loadings, for technical applications involving, e.g., the transport of energy, protection against arcing or discharge. Designing conductive parts requires certain know‐how, as many parameters influence the final electrical conductivity, and many other requirements have to be fulfilled. This paper highlights the impact of the carbon black (CB) type and loading, the polymer type, and the compounding conditions on the conductive, mechanical, dispersion, and flow properties of various plastics compounds. The study especially positions a unique family of low surface area (LSA) CCBs, suggests means to make conductive parts with compounding and transformation ease, and points out that more conductive additive does not automatically give the best overall performance. J. VINYL. ADDIT. TECHNOL., 12:14–18, 2006. © 2006 Society of Plastics Engineers  相似文献   
100.
    
This contribution presents coupling of laws for shear flow and wall slipping by the shear stress at the slipping interface. It includes the special case of Coulombian friction postulated by Uhland as well as the assumption of a constant sliding velocity along the flow channel according to Mooney. As an example, Ostwald and de Waele's law of shear thinning flow is combined with a shear stress of sliding depending on internal pressure by a power law. Examined feedstocks for metal injection molding showed a rheological behavior according to the model presented.  相似文献   
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