利用均匀设计试验进行混凝土配合比优化

提出了混凝土配合比试验的均匀设计方法,采用逐步回归法对试验数据进行回归拟合,以经济成本为目标函数,利用目标规划的方法进行混凝土配合比优化．     

一维驱动二维跟踪太阳自动跟踪系统设计

本文从对太阳方位变化规律的分析计算入手,利用天文时间来提供准确可靠的自动跟踪信号,并采用一维驱动实现二维精密跟踪的新技术。依此所设计的新型太阳能聚光器自动跟踪系统与同类产品相比,具有准确可靠、抗干扰能力强、成本低、方便实用等特点;这对于通过聚光方式推动太阳能应用具有重大的现实意义。     

干涉型光纤水听器灵敏度校准方法研究

研究了利用贝塞尔函数比值来估算得到干涉型光纤水听器光相移的方法,而得到光纤水听器的相移灵敏度。对理论模型进行了模拟,并对一推挽式干涉型零差光纤水听器进行了实际校准。     

Advances in Soft Materials for Sustainable Electronics

In the current shift from conventional fossil-fuel-based materials to renewable energy,ecofriendly mate-rials have attracted extensive research interest due to ...     

Characterization of residual stresses from cold expansion using spatial statistics

Residual stress fields from cold expansion have been widely used to extend the fatigue life of aircraft structures. However, the spatial statistical character of these residual stress fields has not been established and has not been incorporated in current analysis methods. The objective of this study was to establish a spatial statistical method to quantify the residual stress field around a cold expanded hole. A framework called the Spatial Analysis of Residual Stress (SpARS) was developed utilizing spatial correlation, response surface modelling techniques and statistical resampling methods to characterize the residual stress field. Our results showed that tolerance bounds on residual stress can be quantified using this method. We also demonstrated the SpARS method using recently published round robin case studies. The newly developed model will be useful for aircraft structural fatigue crack growth analyses to incorporate residual stress fields for extending inspection intervals for fatigue and fracture critical structures.     

Heat-Killed Enterococcus faecalis EF-2001 Induces Human Dermal Papilla Cell Proliferation and Hair Regrowth in C57BL/6 Mice

Minoxidil is the most widely used treatment for hair growth, but has been associated with several side effects. In this study, we investigated the effects of heat-killed Enterococcus faecalis EF-2001 on hair loss prevention and regrowth using human dermal papilla cells and male C57BL/6 mice. To examine the effects of EF-2001, we used minoxidil as the positive control. In the in vitro experiments, EF-2001 treatment (75–500 μg/mL) led to the proliferation of human dermal papilla cells in a concentration-dependent manner. In the in vivo experiment, the topical application of 200 µL EF-2001 on the dorsal surface of C57BL/6 male mice led to hair growth. Changes in hair regrowth were examined by visual comparison and hematoxylin and eosin staining of skin sections. We also determined the expression levels of marker genes (Wnt) and growth factors (fibroblast growth factor, insulin growth factor 1, and vascular endothelial growth factor) in the skin tissues of the back of each mouse using a quantitative polymerase chain reaction. EF-2001 accelerated the progression of hair regrowth in mice and promoted hair-follicle conversion from telogen to anagen, likely by increasing the expression levels of growth factors and marker genes.     

Towards 3D Bioprinted Spinal Cord Organoids

Three-dimensional (3D) cultures, so-called organoids, have emerged as an attractive tool for disease modeling and therapeutic innovations. Here, we aim to determine if boundary cap neural crest stem cells (BC) can survive and differentiate in gelatin-based 3D bioprinted bioink scaffolds in order to establish an enabling technology for the fabrication of spinal cord organoids on a chip. BC previously demonstrated the ability to support survival and differentiation of co-implanted or co-cultured cells and supported motor neuron survival in excitotoxically challenged spinal cord slice cultures. We tested different combinations of bioink and cross-linked material, analyzed the survival of BC on the surface and inside the scaffolds, and then tested if human iPSC-derived neural cells (motor neuron precursors and astrocytes) can be printed with the same protocol, which was developed for BC. We showed that this protocol is applicable for human cells. Neural differentiation was more prominent in the peripheral compared to central parts of the printed construct, presumably because of easier access to differentiation-promoting factors in the medium. These findings show that the gelatin-based and enzymatically cross-linked hydrogel is a suitable bioink for building a multicellular, bioprinted spinal cord organoid, but that further measures are still required to achieve uniform neural differentiation.     

Green revolution in electronic displays expected to ease energy and health crises

The technological revolution of long-awaited energy-saving and vision-friendly displays represented by bistable display technology is conning.Here we discuss methods,challenges,and opportunities for implementing bistable displays in terms of molecular design,device structure,further expansion,and required criteria,hopefully benefiting the light-related community.