Clinically applicable bulk isolation of blood CD34+ cells for autografting in children

The quality of population-based cancer registries has been measured by the indices of the proportion of total incident cases (DCO%) registered by death certificate only (DCO), and the ratio of incidence to mortality (I/D ratio). Recently it has been recommended that DCO% should be used as an index for the reliability of diagnosing cancers and that the proportion of cases first notified via death certificate (DCN, DCN%) be used as an index for the completeness of registration. Parkin introduced a method to estimate the registration rate, the estimated proportion of the "true incidence" that are registered in population-based registries. We recommend a modified method for estimating the registration rate for cancer registries where DCN% is relatively high, as it is in Japan, as Parkin's method may overestimate the registration rate. The method is as follows: the registration rate = (1-DCN% x 1/D ratio)/(1-DCN%). The registration rates at the Osaka Cancer Registry between 1966 and 1992 were estimated using our method. During this period, the yearly registration rate was 74.6-78.4% for males and 69.1-73.3% for females. When the cancer cases were looked at according to site, the yearly registration rate was 74.2-81.6% for stomach cancer, 81.2-89.3% for lung cancer, and 71.3-76.9% for uterine cancer. These results show that the registration rate is high for cancers that have an unfavorable prognosis and low for cancers that have a favorable prognosis. We recommend that all cancer registries in Japan calculate the completeness of registration by utilizing DCN defined as the sum of DCO plus cases not reported as cancer but with supportive clinical information of such obtained through survey of the registry for DCN.     

Blind source extraction of long-term physiological signals from facial thermal images

The amount of mental work using information equipment has been increasing because of a rapid growth of an information society. Accumulation of short-term mental work can cause various stresses and a disturbance of circadian rhythm and lead to fatigue, anxiety, and distraction. Estimation and understanding the physiopsychological states is desired for decreasing or controlling stresses to maintain health. There have been several investigations on the assessment of short-term physiopsychological states using infrared thermography. However, the method has been used rarely for assessing long-term physiopsychological states. In the present study, extraction of independent components related to long-term physiological signals is attempted by applying independent component analysis to facial thermal images obtained over 6 months (July–December). Furthermore, multiple regression analysis is attempted to create psychological model by facial thermal images. As the result, extracted independent components are shown to represent the strong features in nasal, mouth, cheek, eyebrow, and forehead regions. Attempting multiple regression analysis, features in nasal and mouth regions contributed to depression or dejection mood, features in cheek, eyebrow and forehead regions contributed to fatigue and features in tip of nasal, eyebrow and mouth regions contributed to state anxiety.     

Comparison of pool boiling CHF of a polished copper block and carbon steel block on a declined slope

This study conducts a critical heat flux (CHF) experiment on a carbon steel block, and the block is positioned on slope that is declined at angles of 5° and 10°. The results of the carbon steel block experiment were then analyzed and compared with the results obtained from a copper block experiment that had been conducted previously at the same test facility. The comparison showed that several different types of phenomena had occurred, and the carbon steel block CHF at both 5° and 10° was much lower than that of the copper block. Detailed images of the heating surface of each material were acquired by a high-speed camera under different heat fluxes and analyzed. The carbon steel block surface generates more bubbles compared to the copper block under the same heat flux, which indicates that the carbon steel block should have a large number of nucleation sites. This causes a higher CHF. Finally, several existing theories on CHF mechanisms were also analyzed in an attempt to explain the difference of copper and carbon steel. It seemed that the contact angle alone was not sufficient to explain the large CHF decrease in the carbon steel block.     

Augmented reality-based block piling game with superimposed collapse prediction

Understanding what cannot be seen is difficult. Physical behavior can be explained on the basis of physical theories even if the behavior cannot be observed. Explanation of what is physically happening in the real world would become easy, however, if annotations were superimposed on the real objects. Herein, the authors demonstrate how an understanding of a physical event can be facilitated by overlapping a real-world situation with a simulation that predicts a future state. This idea is demonstrated in a game application in which a player stacks blocks into a pile until it collapses. In general, it is easy to estimate whether a block on the edge of a table will fall or not. However, it is more difficult to predict whether a stack of many blocks will collapse, and in what manner the stack will collapse. Even though previous research has demonstrated that the problem of how two-dimensionally stacked blocks collapse can be reduced to solving a sequence of convex quadratic programs, algorithms for convex quadratic programs require massive computational resources. Hence, the authors developed a fast and new algorithm based on a linear program. The proposed algorithm realizes real-time simulation based on physics that superimposes predicted collapse. The block that is predicted to fall is superimposed on the real block with a lit background projection. The system was evaluated in an experiment, and superimposed augmented reality annotation was observed to be efficient. The system was also demonstrated in game contests and received positive feedback and comments.     

Acoustic Resonance in Exhaust Gas Economizer Tube Bundles Prediction and Suppression of Resonance

The tendency for air column resonance generation in structures with a constant volume behind a tube array like that of an exhaust gas economizer has been reported, but many points remain unclear with respect to the mechanism and conditions that generate acoustical resonance. When acoustical resonance is generated, in reality, prevention and suppression measures are implemented by inserting a baffle plate into the ducts through a process of trial and error. The purpose of this study is to clarify the mechanism of generation of acoustical resonance, and to establish an appropriate measure to prevent such resonance. Noise generated in an exhaust gas economizer was correlated with the flow inside the tube array and experimentally analyzed, and the mechanism for resonance generation was considered. In addition, the effectiveness of a baffle plate positioned in order to prevent resonance was investigated. We have successfully employed a single baffle plate to suppress resonance.     

Optical manipulation of multiple stable states in photorefractive four-wave mixing

Abstract

We propose an approach to manipulate the convergence in multiple solutions of phase conjugate reflectivity in photorefractive four-wave mixing. Although a method forcibly adding a π-phase shift to an incident beam has been already proposed to control the reflectivity, some restrictions have been required in the boundary conditions for the successful operation. Here, we control the reflectivity with the boundary conditions in which the phase shift operation is ineffective by itself. In our method, the phase shift operation is combined with the procedure of turning an incident beam on and off. With a numerical analysis of four-wave mixing, we show that our new approach brings drastic change in the spatial distribution of the index grating and leads the phase conjugate reflectivity which was not manipulated previously.