Genetic mechanism and development of the unsteady Sarvak play of the Azadegan oil field,southwest of Iran

The upper Cretaceous Sarvak reservoir in the Azadegan oil field of southwest Iran has its oil–water contact nearly horizontal from the north to the center and dips steeply from the center to the south.The purpose of this paper is to interpret this abnormal reservoir feature by examining the accumulation elements,characteristics,and evolution based on the 3D seismic,coring,and well logging data.Generally,in the field,the Sarvak reservoir is massive and vertically heterogeneous,and impermeable interlayers are rare.The distribution of petrophysical properties is mainly dominated by the depositional paleogeomorphology and degrades from north to south laterally.The source is the lower Cretaceous Kazhdumi Formation of the eastern Dezful sag,and the seal is the muddy dense limestone of the Cenozoic Gurpi and Pebdeh Formations.Combined with the trap evolution,the accumulation evolution can be summarized as follows: the Sarvak play became a paleo-anticlinal trap in the Alpine tectonic activity after the late Cretaceous(96 Ma) and then was relatively peaceful in the later long geologic period.The Kazhdumi Formation entered in the oil window at the early Miocene(12–10 Ma) and charged the Sarvak bed,thus forming the paleo-reservoir.Impacted by the ZagrosOrogeny,the paleo-reservoir trap experienced a strong secondary deformation in the late Pliocene(4 Ma),which shows as the paleo-trap shrank dramatically and the prelow southern area uplifted and formed a new secondary anticline trap,hence evolving to the current two structural highs with the south point(secondary trap) higher than the north(paleo-trap).The trap deformation broke the paleoreservoir kinetic equilibrium and caused the secondary reservoir adjustment.The upper seal prevented vertical oil dissipation,and thus,the migration is mainly in interior Sarvak bed from northern paleo-reservoir to the southern secondary trap.The strong reservoir heterogeneity and the degradation trend of reservoir properties along migration path(north to south) made the reservoir readjustment extremely slow,plus the short and insufficient re-balance time,making the Sarvak form an ‘‘unsteady reservoir'which is still in the readjustment process and has not reached a new balance state.The current abnormal oil–water contact versus the trap evolutionary trend indicates the secondary readjustment is still in its early stage and has only impacted part of paleo-reservoir.Consequently,not all of the reservoir is dominated by the current structure,and some parts still stay at the paleo-reservoir form.From the overview above,we suggest the following for the future development: In the northern structural high,the field development should be focused on the original paleoreservoir zone.In the southern structural high,compared with the secondary reservoir of the Sarvak with the tilted oil–water contact and huge geologic uncertainty,the lower sandstone reservoirs are more reliable and could be developed first,and then the deployment optimized of the upper Sarvak after obtaining sufficient geological data.By the hints of the similar reservoir characteristics and tectonic inheritance with Sarvak,the lower Cretaceous Fahliyancarbonate reservoir is also proved to be an unsteady reservoir with a tilted oil–water contact.     

稀土化合物浆料对CVD金刚石厚膜的刻蚀

ＣＶＤ金刚石厚膜具有极高的硬度,使得对其进行表面抛光极为困难．传统的机械抛光方法既不经济又耗费时间,而一些新的抛光技术又由于实验条件限制而难以推广．针对以上情况,我们寻求到一种新的化学刻蚀方法,即利用稀土化合物浆料对金刚石厚膜生长表面进行刻蚀,破坏表面的晶粒使之成为晶骸,降低表面的耐磨性,以提高表面粗糙的金刚石厚膜的抛光效率．     

传动带制造技术与工艺装备(二)

<正>(接上期)(3)耐油同步带自上世纪60年代,美国通用公司首次将同步带用于新开发的顶制式凸轮(OHC)发动机替代原来使用的滚珠链条以来,由于同步带具有同步性能好、噪音小、无需润滑、重量轻、成本低和     

油菜素甾醇对章姬草莓贮藏品质的影响

目的 探讨章姬草莓果实的贮藏特性与油菜素甾醇(brassinosteroids, BRs)的关系。方法 以章姬草莓为供试材料, 以蒸馏水为对照, 通过不同浓度的BRs溶液(5、10、15 μmol/L)喷洒草莓果实, 观察BRs对其失重率、腐烂情况等贮藏品质的影响。结果 经过BRs处理章姬草莓果实后质量损失明显降低, 腐烂速度减缓, 特别是在10 μmol/L浓度喷洒下章姬草莓果实失重率、可溶性固形物和维生素C (vitamin C, VC)含量的损失均显著低于对照组。在第6 d时, 10 μmol/L BRs处理组章姬草莓果实比对照组的VC含量高1.8倍, 硬度高19.2%; 腐烂率、腐烂指数、丙二醛含量的增加量均显著低于对照组(P<0.05); 对照组比10 μmol/L BRs处理组章姬草莓果实丙二醛含量高1.27倍, 腐烂率高13%, 腐烂指数高20%。结论 10 μmol/L BRs喷洒下对延长章姬草莓果实的贮藏时间具有较好的效果。     

The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease

Human bleomycin hydrolase (hBH) catalyzes deamidation of the anticancer drug bleomycins (BLM). This enzyme is involved in BLM detoxification and drug resistance. Herein, we report the putative BLM-binding site and catalytic mechanism of hBH. The crystal structures and biochemical studies suggest that hBH cleaves its C-terminal residue without significant preference for the type of amino acid, and therefore can accordingly accommodate the β-aminoalanine amide moiety of BLM for deamidation. Interestingly, hBH is capable of switching from a cysteine protease to a serine protease that is unable to cleave the secondary amide of hBH C-terminus but reacts with the primary amide of BLMs.     

紫苏籽油化学组成与检测技术研究进展

紫苏籽油是一种富含多不饱和脂肪酸的食用植物油,从食药同源植物紫苏成熟的种子中获得。紫苏籽含有脂肪、蛋白质、脂肪酸、甾醇、脂溶性维生素等多种营养物质,其主要成分是α-亚麻酸。紫苏籽油是迄今为止发现的草本植物种子油中α-亚麻酸含量最高的食用油,在医药和食品加工方面具有很高的利用价值。通过对国内外紫苏籽油研究进展综述,本文总结了紫苏籽油的功效作用、理化性质、营养成分及检测方法,为后续紫苏籽油及其副产物的开发利用提供参考依据。     

9-O-Terpenyl-Substituted Berberrubine Derivatives Suppress Tumor Migration and Increase Anti-Human Non-Small-Cell Lung Cancer Activity

Lung cancer is one of the most common cancers and the leading cause of death in humans worldwide. Non-small-cell lung cancer (NSCLC) accounts for approximately 85% of lung cancer cases and is often diagnosed at a late stage. Among patients with NSCLC, 50% die within 1 year after diagnosis. Even with clinical intervention, the 5-year survival rate is only approximately 20%. Therefore, the development of an advanced therapeutic strategy or novel agent is urgently required for treating NSCLC. Berberine exerts therapeutic activity toward NSCLC; therefore, its activity as an antitumor agent needs to be explored further. In this study, three terpenylated-bromide derivatives of berberrubine were synthesized and their anti-NSCLC activities were evaluated. Each derivative had higher anti-NSCLCs activity than berberrubine and berberine. Among them, 9-O-gernylberberrubine bromide (B4) and 9-O-farnesylberberrubine bromide (B5) showed greater growth inhibition, cell-cycle regulation, in vitro tumorigenesis suppression, and tumor migration reduction. In addition, some degree of apoptosis and autophagic flux blocking was noted in the cells under B4 and B5 treatments. Our study demonstrates that the berberrubine derivatives, B4 and B5, exhibit impressive anti-NSCLC activities and have potential for use as chemotherapeutic agents against NSCLC.     

汽车传动带行业现状及发展趋势

<正>汽车传动带是发动机的重要部件,它包括用于驱动发动机前端辅件如发电机、转向助力泵、风扇、水泵、增压器以及空调压缩机等部件传动的汽车V带和多楔带,以及用于凸轮轴与曲轴之间的正时传动的同步带(正时皮带)。汽车传动带的技术进步大     

中心距10 μm截止波长2.6 μm的延伸波长InGaAs焦平面探测器

采用ICP (inductively coupled plasma etching) 刻蚀与湿法腐蚀相结合的方式, 研制了像元中心距为10μm、截止波长2. 6μm的p-i-n型10×10元延伸波长In Ga As探测器.不同温度下的电流—电压特性研究和激活能分析, 显示了器件优异的暗电流特性.在室温下, -10 mV偏压时器件的暗电流和优质因子R0A分别为0. 45 nA和14. 7Ω·cm2, 量子效率可达到63%.为了证实像元中心距减小并未影响器件性能, 与同种材料中心距30μm的InGaAs焦平面阵列进行了对比分析.相似的实验结果进一步证明了工艺的可行性, 对今后实现高密度、大面阵延伸波长InGaAs探测器具有重要的指导意义.     

数控技术应用技能型人才培养模块的构建

数控技术应用专业领域技能型人才的培养,必须以突出职业技能培养为特色,实行“双证书”教育,加强实践教学环节,文章按照“阶段、渐进”的方式和顺序,阐述了数控技术应用专业实践教学体系实践教学模块的构建。