Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions

We investigated clinical efficacy of green tea extracts (polyphenon E; poly E and (-)-epigallocatechin-3-gallate [EGCG]) delivered in a form of ointment or capsule in patients with human papilloma virus (HPV) infected cervical lesions. Fifty-one patients with cervical lesions (chronic cervicitis, mild dysplasia, moderate dysplasia and severe dysplasia) were divided into four groups, as compared with 39 untreated patients as a control. Poly E ointment was applied locally to 27 patients twice a week. For oral delivery, a 200 mg of poly E or EGCG capsule was taken orally every day for eight to 12 weeks. In the study, 20 out of 27 patients (74%) under poly E ointment therapy showed a response. Six out of eight patients under poly E ointment plus poly E capsule therapy (75%) showed a response, and three out of six patients (50%) under poly E capsule therapy showed a response. Six out of 10 patients (60%) under EGCG capsule therapy showed a response. Overall, a 69% response rate (35/51) was noted for treatment with green tea extracts, as compared with a 10% response rate (4/39) in untreated controls (P<0.05). Thus, the data collected here demonstrated that green tea extracts in a form of ointment and capsule are effective for treating cervical lesions, suggesting that green tea extracts can be a potential therapy regimen for patients with HPV infected cervical lesions.     

A Novel Body-tied Silicon-On-Insulator(SOI) n-channel Metal-Oxide-Semiconductor Field-Effect Transistor with Grounded Body Electrode

A novel body-tied silicon-on-insulator(SOI) n-channel metal-oxide-semiconductor field-effect transistor with grounded body electrode named GBSOI nMOSFET has been developed by wafer bonding and etch-back technology. It has no floating body effect such as kink phenomena on the drain current curves, single-transistor latch and drain current overshoot inherent in a normal SOI device with floating body. We have characterized the interface trap density, kink phenomena on the drain current (I_DS-V_DS) curves, substrate resistance effect on the I_DS-V_DS curves, subthreshold current characteristics and single transistor latch of these transistors. We have confirmed that the GBSOI structure is suitable for high-speed and low-voltage VLSI circuits.     

Helicoseir as Shape of a Rotating String (I): 2D Theory and Simulation Using ANCF

A physically simple but mathematically cumbersome problem of rotating heavy string with one fixed top point was studied. A nonlinear equation of its two-dimensional shapes of relative equilibrium was obtained and solved numerically. A linear case of small displacements was analyzed in terms of Bessel functions. The qualitative and quantitative behavior of the problem is discussed with the help of a bifurcation diagram. Dynamics of the two-dimensional model near the equilibrium positions were studied with the help of a simulation using the absolute nodal coordinate formulation (ANCF); the equilibriums were found to be instable. The reason for instability is explained using a variational principle. The outlines for further full three-dimensional analysis are briefly proposed in this paper, and the full derivation will be explained in the next paper.     

Efficient traffic prediction scheme for real-time VBR MPEG videotransmission over high-speed networks

The efficient transportation of real-time variable bit rate (VBR) video traffic in high-speed networks is currently an active area of research. The capability to predict VBR video traffic can significantly improve the effectiveness of numerous management tasks, including dynamic bandwidth allocation and congestion control. This paper proposes an adaptive traffic prediction method for VBR MPEG videos, a major multimedia application. Rapid traffic variations due to scene changes are analyzed, then a prediction scheme using the identification of scene changes related to I and P frames is presented. For predicting multiplexed MPEG traffic, a prediction interval is derived that represents a highly correlated traffic sequence. In addition, to reduce the prediction error, a less fluctuating signal instead of the original multiplexed traffic is used as the input for the predictor. Simulation results show that the proposed method is able to predict the original traffic more accurately than the conventional LMS method     

Generation and Mobility of Electronic Charge Carriers in Y1Ba2Cu3Ox

The Hall effect and the conductivity of Y₁Ba₂Cu₃O_x have been measured together for quenched specimens at room temperature as functions of oxygen content (x) in the range of 6 < × < 7. It has been reconfirmed that a hole is generated per every oxygen atom incorporated in the orthorhombic phase (x > 6.5) and per every two oxygen atoms in the tetragonal phase (x < 6.5). The exothermic enthalpy change for hole generation is 2 times or more larger in the tetragonal than in the orthorhombic phase. The mobility of the majority carrier holes has been found to vary discontinuously crossing the phase boundary (x ⋍ 6.5), reflecting a first-order phase transition for these quenched specimens. It is independent of oxygen content in each structure: 0.34 ± 0.03 cm²/(V·s) in the tetragonal phase and 0.51 ± 0.06 cm²/(V·s) in the orthorhombic phase.     

Investigation of driving performance, vection, postural sway, and simulator sickness in a fixed-based driving simulator

This paper reports the results of a pilot study conducted to determine whether there is a relationship between simulator sickness and measures of driver inputs, vection, and postural sway, in a fixed base driving simulator. Seven males and four females performed a series of alternating left and right turns (20 each), with straigth-aways inbetween. The task was designed to promote experiences of circular and linear vection, and associated sway. It was hypothesized that greater driver inputs (i.e., steering wheel and braking activity; deviation from the centerline) would correlate: with reports of vection and measures of postural sway. Ten of the eleven subjects reported moderate sickness, which precluded any statistical comparisons between “sick” and “not sick” however, there was a significant tendency for persons who reported vection to also report sickness. There were no gender differences in reported incidence of vection or sickness, however, males tended to exhibit greater lateral velocity. The next phase of investigation will necessitate reducing the strength of the stimulus (i.e., require less turns) to increase variability of sickness scores amongst subjects and permit comparisons between “sick” and “not sick.” Measurement considerations include increasing the sensitivity of vection ratings, and examination of the timecourse for the development of postural sway.     

Frequency tuning technique for Gm-C filters

A frequency tuning technique based on an envelope locked loop is proposed for Gm-C filters. A degenerated integrator is used as the master circuit to eliminate the problems associated with the DC offset of the operational transconductance amplifier (OTA)