低温地板辐射采暖应用分析

从系统原理、设计以及施工分析了低温地板辐射采暖的应用，指出低温地板辐射采暖系统可以实现按用热量合理计量，进行室内温度的调节，改变室内热环境，克服水力垂直失调现象。具有其它采暖系统不可比拟的优点，是室内采暖系统的发展方向。     

难溶有机药物阿莫西林纳米结构的制备

在表面活性剂SDS的辅助下,运用简单的化学沉淀法制备了三种阿莫西林纳米结构.运用扫描电镜和红外光谱对制备的阿莫西林进行了形貌、尺寸和化学结构的表征.实验发现通过调节阿莫西林钠溶液的pH值,可以得到阿莫西林纳米和微米颗粒纳米带和纳米纤维,在一定程度上实现了这一难溶有机药物的可控生长.     

Nicotinamide Mononucleotide Supplementation Improves Mitochondrial Dysfunction and Rescues Cellular Senescence by NAD+/Sirt3 Pathway in Mesenchymal Stem Cells

In vitro expansion-mediated replicative senescence has severely limited the clinical applications of mesenchymal stem cells (MSCs). Accumulating studies manifested that nicotinamide adenine dinucleotide (NAD⁺) depletion is closely related to stem cell senescence and mitochondrial metabolism disorder. Promoting NAD⁺ level is considered as an effective way to delay aging. Previously, we have confirmed that nicotinamide mononucleotide (NMN), a precursor of NAD⁺, can alleviate NAD⁺ deficiency-induced MSC senescence. However, whether NMN can attenuate MSC senescence and its underlying mechanisms are still incompletely clear. The present study herein showed that late passage (LP) MSCs displayed lower NAD⁺ content, reduced Sirt3 expression and mitochondrial dysfunction. NMN supplementation leads to significant increase in intracellular NAD⁺ level, NAD⁺/ NADH ratio, Sirt3 expression, as well as ameliorated mitochondrial function and rescued senescent MSCs. Additionally, Sirt3 over-expression relieved mitochondrial dysfunction, and retrieved senescence-associated phenotypic features in LP MSCs. Conversely, inhibition of Sirt3 activity via a selective Sirt3 inhibitor 3-TYP in early passage (EP) MSCs resulted in aggravated cellular senescence and abnormal mitochondrial function. Furthermore, NMN administration also improves 3-TYP-induced disordered mitochondrial function and cellular senescence in EP MSCs. Collectively, NMN replenishment alleviates mitochondrial dysfunction and rescues MSC senescence through mediating NAD⁺/Sirt3 pathway, possibly providing a novel mechanism for MSC senescence and a promising strategy for anti-aging pharmaceuticals.     

改进型SIRT法进行电磁波CT反演应用研究

利用声波、地震波CT中广泛应用的SIRT法对BPT法进行改进,用“dij／li”替换“dij”作为第i条射线在第j个网格中的权值,使那些较小的dij（dij=li）在传统的BPT法中权值微小,而在改进型BPT法中却有最大的权值,用其计算结果作为CT反演计算的初值,同时将BPT法融合到SIRT法中去,使射线与网格符合“近则优”的原则,称之为改进型SIRT法,能起到有效地压制野外资料的外界干扰影响。该方法于电磁波CT在生产实践应用中取得显著成效。     

Rational Design of Charge‐Neutral,Near‐Infrared‐Emitting Osmium(II) Complexes and OLED Fabrication

A new series of charge neutral Os(II) isoquinolyl triazolate complexes ( 1 – 4 ) with both trans and cis arrangement of phosphine donors are synthesized, and their structural, electrochemical and photophysical properties are established. In sharp contrast to the cis‐arranged complexes 2 – 4 , the trans derivative 1 , which shows a planar arrangement of chromophoric N‐substituted chelates, offers the most effective extended π‐delocalization and hence the lowest excited state energy gap. These complexes exhibit phosphorescence with peak wavelengths ranging from 692–805 nm in degassed CH₂Cl₂ at room temperature. Near‐infrared (NIR)‐emitting electroluminescent devices employing 6 wt % of 1 (or 4 ) doped in Alq₃ host material are successfully fabricated. The devices incorporating 1 as NIR phosphor exhibit fairly intense emission with a peak wavelength at 814 nm. Forward radiant emittance reaches as high as 65.02 µW cm^?2, and a peak EQE of ～1.5% with devices employing Alq₃, TPBi and/or TAZ as electron‐transporting/exciton‐blocking layers. Upon switching to phosphor 4 , the electroluminescence blue shifts to 718 nm, while the maximum EQE and radiance increase to 2.7% and 93.26 (μW cm^?2) respectively. Their performances are optimized upon using TAZ as the electron transporting and exciton‐blocking material. The OLEDs characterized represent the only NIR‐emitting devices fabricated using charge‐neutral and volatile Os(II) phosphors via thermal vacuum deposition.     

Bio-hydrogen production enhancement by co-cultivating Rhodopseudomonas palustris WP3-5 and Anabaena sp. CH3

Photobiological H₂ production is a promising method for renewable energy development. An innovative system that co-cultivating Rhodopseudomonas palustris WP3-5 and Anabaena sp. CH3 was carried out to estimate the effect of co-cultivation on H₂ production enhancement. H₂ production prolongation and enhancement were observed due to the light and metabolic compatibility of these two strains. Co-culture system served by acetate and fructose as carbon source can accumulate H₂ in 140.8 mL, almost double than the sum of individuals. Moreover, the enhancement of H₂ production was significantly affected by the mixed ratio of two strains. The mixed ratio (WP3-5:CH3) of 1:2 showed a highest H₂ production rate in 44.8 mL-H₂/L-culture/h, and both 2:1 and 1:2 exhibited a relatively high substrate conversion efficiency during the latest period of cultivation, whereas the mixed ratio of 1:1 and 3:1 only revealed a prolongation in H₂ production due to metabolic compatibility of two strains.     

镀银编织铜丝与铜层微电阻点焊接头组织与性能研究

研究了0.1 mm镀银编织铜丝与0.07 mm厚度超薄纯铜层微电阻点焊接头的微观组织和力学性能,分析了不同参数对接头力学性能的影响,采用扫描电子显微镜对典型接头的微观组织结构特征进行了分析。结果表明,当焊接热量足够时,焊点接头主要为钎焊－熔焊混合连接机制,其形成过程中经历银元素润湿铺展、银元素扩散、铜元素熔化和金属凝固四个过程;焊点连接面处组织致密,存在铜银两相与单富铜相构成连接界面形态,后者焊点微观组织结构含有熔焊的特征;试验所用参数范围内,焊点的最大抗剪力可达45 N,焊接时间与焊接电流均在一定的范围内对焊点性能影响较大,当电阻产热达到饱和区间,焊点抗剪切性能变化不大。     

新趋势下住区规划设计策略的探讨

当前,经济的高速发展大大促进了城市化进程,城市规模的不断扩大,让城市近郊的住区逐渐形成,由于这些住区不同于以往城市中心区里的小区,因此此文试对这种新趋势下的住区规划设计提出分析和探讨。     

哈尔滨医科大学附属第一医院外科病房楼——从医院管理模式出发的功能设计

醫院建築的功能布局因外在因素的不同而千變萬化,醫院管理模式、服務患者的來源及特性、醫療資源的分布,以及醫療技術、醫療裝備、建築技術、建築設備的發展與變化等,都對之有所影响。建設是一時的,運營是長久的。設計中我們發現,業主除了對醫院硬件設施有量和質的建設需求