Optimization of antioxidant peptide production from grass carp sarcoplasmic protein using response surface methodology

The sarcoplasmic protein was extracted from the muscle of grass carp, a Chinese freshwater carp, and was hydrolyzed with five proteases to produce antioxidant peptides. Papain hydrolysate was found to have the greatest activity against lipid peroxidation. Response surface methodology (RSM) was applied to optimize the hydrolysis conditions (including enzyme to substrate ratio, time and temperature). The minimum EC₅₀ value (317.25 μg/mL) which signified the maximum antioxidant activity was obtained at an enzyme to substrate ratio of 0.79%, an incubation time of 5.69 h and an incubation temperature of 52.15 °C, which was in agreement with the predicted value (313.99 μg/mL) estimated by RSM within a 95% confidence interval. Also, it was found that moderate denaturation of the sarcoplasmic protein and a modest increase in the degree of hydrolysis promoted the antioxidant activities of the hydrolysates. Oligopeptides (< 3 kDa) contributed more to the antioxidant activity than polypeptides.     

High-speed small-scale InGaP/GaAs HBT technology and itsapplication to integrated circuits

We have developed the advanced performance, small-scale InGaP/GaAs heterojunction bipolar transistors (HBTs) by using WSi/Ti base electrode and buried SiO₂ in the extrinsic collector. The base-collector capacitance C_BC was further reduced to improve high-frequency performance. Improving the uniformity of the buried SiO ₂, reducing the area of the base electrode, and optimizing the width of the base-contact enabled us to reduce the parasitic capacitance in the buried SiO₂ region by 50% compared to our previous devices. The cutoff frequency f_T of 156 GHz and the maximum oscillation frequency f_max of 255 GHz were obtained at a collector current I_C of 3.5 mA for the HBT with an emitter size S_E of 0.5×4.5 μm², and f_T of 114 GHz and f_max of 230 GHz were obtained at I_C of 0.9 mA for the HBT with S_E of 0.25×1.5 μm². We have also fabricated digital and analog circuits using these HBTs. A 1/8 static frequency divider operated at a maximum toggle frequency of 39.5 GHz with a power consumption per flip-flop of 190 mW. A transimpedance amplifier provides a gain of 46.5 dB·Ω with a bandwidth of 41.6 GHz at a power consumption of 150 mW. These results indicate the great potential of our HBTs for high-speed, low-power circuit applications     

Study on creep-fatigue evaluation procedures for high-chromium steels—Part I: Test results and life prediction based on measured stress relaxation

Strong demand for improving thermal efficiency of power generation plants promoted the use of high-chromium steels, which have high creep strength and corrosion resistance. Aiming at cost reduction for future nuclear power plants, these materials are also regarded as candidates for structural materials, being favoured for lower thermal expansion rate compared with austenitic stainless steels. In structural design and life management of these plants, failure due to the combination of fatigue and creep damages has been considered as an important phenomenon to be evaluated, in addition to simple creep failure under sustained loading such as inner pressure. The author has been conducting a series of creep-fatigue tests for three types of high-chromium steels used in fossil power plants and the applicability of life prediction methods has been studied. It was found that the time fraction rule gives a relatively small amount of creep damage and overpredicts the failure life, whereas a simple ductility exhaustion method provides very large creep damage which leads to too conservative prediction of failure lives. A modified ductility exhaustion method developed on the re-definition of creep damage as a ductility consumer gave a moderate amount of creep damage and provided reasonable life predictability. Moreover, an empirical formula was derived which can represent the life reduction in compressive hold tests as a function of pure fatigue life and hold time.     

Modification of Shockley surface state by long-chain n-alkane: Photoemission study on tetratetracontane/Au(111) interface

Modification of quasi two-dimensional surface electron system on Au(111) with adsorption of long-chain n-alkane molecule n-CH₃(CH₂)₄₂CH₃ (tetratetracontane: TTC) was investigated by angle-resolved photoemission spectroscopy. Significant modification of the energy band structure of the Shockley surface state was induced by the adsorption of TTC monolayer with “flat-on” structure. The energy shift of the Shockley surface state toward the Fermi level reaches about 160 meV at Γ? point (k = 0 Å^− 1). The possible origin of the stabilization of the surface electron system with TTC monolayer is discussed.     

A new recovery process of carbon dioxide from alkaline carbonate solution via electrodialysis

Bipolar membrane electrodialysis is applied to CO₂ recovery from alkaline carbonate solution. CO₂ in flue gas is captured by an alkaline hydroxide absorbing solution to form an alkaline carbonate solution. The captured CO₂ is recovered from the alkaline carbonate solution via bipolar membrane electrodialysis, and the alkaline solution is regenerated simultaneously. To reduce the power requirement for CO₂ recovery, this study considers optimal design and operation. Three membrane arrangements were compared, and the results indicate the membrane arrangement comprising a bipolar membrane and cation exchange membrane is the most energy saving. With further optimization of operation conditions, the minimum power requirement for CO₂ recovery was reduced to 2.1 MJ/kg‐CO₂ (or 2.1 GJ/t‐CO₂). © 2009 American Institute of Chemical Engineers AIChE J, 2009     

Improving sinterability of ceramics using hybrid microwave heating

Microwave processing, as a new method for sintering ceramics, has key advantages such as increased heating rate, uniform heating and reduced cost compared to conventional methods. It is generally accepted that microwave sintering can improve the macroscopic mechanical performances of ceramics, however, the performances of microwave-sintered ceramics on the microscopic scale are rarely investigated. In the present study, the ceramics are sintered by hybrid microwave sintering (HMS), which combines the characteristics of microwave heating and conventional heating. To evaluate the homogeneous performance of the sintered ceramics, the behaviors of thermal residual stress distribution in the microwave-sintered and conventionally sintered ceramics were investigated by X-ray diffraction technique. The thermal residual stress investigation shows microwaves can sinter ceramics in entire volume while offering improved mechanical properties. Subsequently, the distribution behaviors of pore ratio and hardness in the ceramics were investigated, respectively. The experiment results confirm that the sinterability of ceramics is homogenously improved by hybrid microwave sintering.     

不同路面条件下轮胎牵引性能数值模拟分析

车辆行驶路面多种多样,如干路面、湿路面、冰路面、雪路面和土路面等.轮胎是车辆与行驶路面之间的唯一接触点,而轮胎牵引性能随着不同路面条件发生相应的变化.轮胎牵引性能是决定车辆安全性能的关键因素,可通过数值模拟的方式研究不同路面条件下轮胎牵引力的变化情况.例如隐-显式有限元方法可用于提高轮胎在干路面条件下的性能,如图1所示,轮胎的预测力和力矩与试验结果吻合.在预测中,有限元分析方法对研究较大侧偏角情况是非常有帮助的.尽管希望对轮胎在其它路面条件下的不同性能进行预测,但目前在数值模拟方面的研究很少,其中一个难点是轮胎与路面的接触问题,不同类型的接触面为研究工作带来一定难度.近几年,解决了流体/结构体相互作用问题的数值模拟方法被用于分析不同路面条件下轮胎的牵引性能.     

Comparison of enteral nutrition with combined enteral and parenteral nutrition in post-pancreaticoduodenectomy patients: a pilot study

Background  

Many clinical studies have demonstrated that early postoperative enteral nutrition (EN) improved the postroperative course. Post-pancreaticoduodenectomy (PD), patients tend to suffer from postoperative nausea, abdominal distention, and diarrhoea, causing difficulty in the introduction of EN. In this pilot study, we investigated the appropriate nutritional mode post-pancreatic surgery.     

Effect of blending on liquefaction of coals

After solvent extraction of Taiheiyo, Miike and Balmer coals using wash oil under nitrogen atmosphere at 370 °C for 30 min, the extraction yield is always within the additivity law. Further studies used Yallourn, Soyakoishi, Taiheiyo, Horonai, Miike, Shin Yubari, Balmer coals and their blends which were hydrogenated in tetralin, wash oil or creosote oil, with or without catalyst, at 400–450 °C under 10 or 3 MPa of initial hydrogen pressure. When hydrogen is available, the additivity law exists for blended coals, but when the hydrogen supply is deficient, the experimental conversion of blended coals is always lower than calculated conversions. This may be due to the faster consumption of the hydrogen by more reactive coals and thus the less reactive coals were unable to react with hydrogen.