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951.
952.
IS Han N Ramamurthy JH Yun U Schaller ME Meyerhoff VC Yang 《Canadian Metallurgical Quarterly》1996,10(14):1621-1626
A novel method to monitor specific peptidase activities in biological samples as complex as undiluted plasma/blood is described. The approach is based on the design of synthetic polypeptide substrates in which di- or triarginine sequences are linked to each other via one or more other amino acids recognized specifically by the peptidase to be determined. Detection of chymotrypsin and renin activities using synthetic substrates P4 (F-R-R-R-F-V-R-R-F-NH2) and P5 (R-R-R-L-L-R-R-L-L-R-R-R), respectively, serves to demonstrate the principles of this new assay system. A polyion-sensitive membrane electrode, prepared by doping polymer films with dinonylnaphthalene-sulfonate (DNNS), is shown to exhibit significant nonequilibrium electromotive force (EMF) responses toward these and other polycationic substrates at microgram/milliliter levels under physiological conditions. The same electrode, however, exhibits much smaller total EMF response toward the shorter fragments of the synthetic peptides generated by peptidase activity; hence, the addition of peptidase to a solution containing the synthetic substrate yields a change in electrode EMF response, the rate of which is proportional to the activity of peptidase present. Other synthetic polycationic peptides as well as natural polycationic peptides (e.g., protamine) that lack specific cleavage sites for chymotrypsin and renin, yet are detected by the DNNS-based membrane electrode, do not elicit any significant change in EMF response in the presence of the peptidases, confirming the feasibility and utility of the proposed bioanalytical method. 相似文献
953.
A two-dimensional finite element model was constructed to analyze the simulated mechanical behavior of a cantilevered fixed partial denture. The variations of the models were made by altering the degree of bone support, the number of splinted abutments, and the length of the pontics. High stress concentrations were observed around the connectors of the fixed prosthesis and the tooth closest to the cantilever. Reduced bone support increased the deflection and stress concentrations. There was reduction in displacement and stress concentration when the teeth were splinted together. To improve the prognosis of the fixed partial denture cantilever, the number of abutments should be increased and the number of pontics decreased. 相似文献
954.
955.
NiTi形状记忆合金基本驱动特性 总被引:2,自引:0,他引:2
研究了预应变NiTi形状记忆合金的基本驱动特性,结果表明,加热和冷却过程回复力存在滞后行为;卸载过程中应力与应变具有与加热、冷却过程相关的非线性关系;卸尖力随卸载应变速率增加而降低,此外研究了预应变NiTi合金丝产生回复力后对外应力的响应行为。 相似文献
956.
S. K. Liu L. Yang D. G. Zhu J. Zhang 《Metallurgical and Materials Transactions A》1994,25(9):1991-2000
A series of Fe-C-X and Fe-C-X1-X2 alloys in which X, X1 and X2 either raise or depress the activity of C iny were investigated by autodilatometer, optical microscopy, and transmission electron microscopy (TEM) to reveal the relations
among the chemical composition, transformation kinetics, and morphology of ferrite plates. The incubation time of austenite
decomposition at the nose temperature in the time-temperature-transformation (TTT) diagrams, the concentration of C in y in
contact with theα/gg boundary, and the growth rate of ferrite were evaluated to estimate the magnitude of the solute drag-like
effect (SDLE) for the different alloying elements used. All the results are consistent qualitatively with the SDLE hypothesis.
This article is based on a presentation made at the Pacific Rim Conference on the “Roles of Shear and Diffusion in the Formation
of Plate-Shaped Transformation Products,” held December 18-22, 1992, in Kona, Hawaii, under the auspices of ASM INTERNATIONAL’S
Phase Transformations Committee. 相似文献
957.
论述了平板玻璃包装技术改进对提高包装质量和企业经济效益的影响,介绍了平板玻璃包装箱(架)的性能,简述了计算机辅助设计及计算机辅助管理在玻璃包装结构设计及包装质量管理中的效用。 相似文献
958.
A finite element (FE) based formulation is utilized to represent the damage-dependent response of laminated composite structures. An internal-state-variable (ISV) approach provides a definition of the stiffness reduction caused by intralaminar crack propagation at the ply level. These ISVs are combined with simple stress criteria to accommodate ply property changes caused by fiber fracture, fiber microbuckling and interior delaminations. A set of orthogonal Ritz vectors are chosen as basis vectors to transform the dynamical equations of motion to a reduced coordinate space. The reduced basis form of the equations provides significant numerical efficiencies, especially for large ordered systems. Furthermore, damping and its variation with damage can be generally represented in any number of vibratory modes. The Newmark integration operator is used to solve the dynamic equations of motion, and equilibrium iterations are performed in each incremental time step to assure convergence. Results are given for laminated beam and plate geometries subjected to dynamic loads. 相似文献
959.
960.
超细铁粉和氧化铁颗粒的研究 总被引:1,自引:1,他引:0
用透射电镜和图像分析仪等研究了超细铁粉和γ-Fe_2O_3粉末的结构、形貌、粒子的平均尺寸以及粒度分布。研究结果表明,多数超细铁粉粒子近似呈球形,并且,铁粉粒子由两相组成,粒子的核心部分是金屑a-Fe,表面的包裹层为氧化物层,它由Fe_3O_4和7-Fe_O_3的混合物组成。氧化层的平均厚度大约占整个粒子直径的20%左右。羰基铁粉粒子(含氧化层)的平均直径为16nm。直径在4~24nm范围的粒子数占总粒子数的91%,而7-Fe_2O_3粉末既有雪茄状粒子,也有小球状粒子。分析表明,球状粒子的平均直径为113nm,雪茄状粒子的平均直径(按<长 宽>/2计算)为148nm。由于超细铁粉粒子很细,且有磁性,制备电镜试样时分散比较困难。本文比较了几种分散方法后,使用了一种较好的分散方法——超声喷管分散法。 相似文献