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101.
Protoporphyria is a genetic disorder in which patients may develop severe protoporphyrin-induced liver damage and require transplantation. Because unique problems occur in the perioperative period and because excess production of protoporphyrin by the bone marrow continues after liver transplantation, the efficacy of this procedure for protoporphyric liver disease is uncertain. We present follow-up of nine patients who underwent liver transplantation. Two patients died within 2 months of transplantation, one from complications of abdominal bleeding and the other from sepsis after bowel perforations. The remaining seven patients had follow-up at 14 months to 8 years after transplantation (mean, 3.8 years). Two of the seven had suffered skin burns from exposure to operating room lights, which healed without scarring. Three had axonal neuropathies in the postoperative period requiring prolonged mechanical ventilation, and motor defects persisted in two. Five patients had normal liver chemistries at follow-up (mean, 3.5 years), with liver biopsy results normal or showing mild portal triad abnormalities, but erythrocyte protoporphyrin levels remained significantly elevated (1,765 +/- 365 mcg/dL; normal, < 65). The other two patients, both of whom had rejection, cytomegalovirus infection, and biliary tract obstruction requiring endoscopic therapy, had a recurrence of protoporphyric liver disease as indicated by liver biopsy features. One died 5 years after transplantation from complications of the liver disease. The other was stable 3.3 years after transplantation and was being monitored for possible retransplantation. Thus, liver transplantation can be performed successfully in patients with protoporphyric liver disease, with intermediate survival rates comparable to the general transplant population. However, disease may recur in the graft, particularly if there are complications that cause cholestasis.  相似文献   
102.
摇臂参数设计方法   总被引:2,自引:0,他引:2  
建立了中小功率内燃机常用摇臂参数化设计模型。采用可变参数构成摇臂结构,并作结构的有限元网络,此后再进行有限元分析,计算出摇的质量、刚度、转动惯量 力。使摇臂的设计归结为几个主要参数的优选。实例分析表明,计算值和实测值基本相符,优选出的摇避设计优于原设计。  相似文献   
103.
The intratracheal instillation of xanthine-xanthine oxidase caused a marked decrease in dynamic respiratory compliance, indicating airway constriction. The constriction was significantly attenuated by fullerenol-1, but not by other agents or receptor antagonists.  相似文献   
104.
Previous analyses of the Wechsler Memory Scale-Revised (WMS-R; Wechsler, 1987) have reported one-, two-, and three-factor solutions and raised questions about the validity of the visual memory subtests. These various findings may stem in part from different methods of analysis, and from the study of different participant samples. To address these issues, we analysed data from the WMS-R and a spatial maze test administered to 154 participants with a history of alcohol dependence. Results from confirmatory factor analysis supported the interpretation of three factors underlying the WMS-R subtests and the spatial maze score in this sample, namely, attention-concentration, immediate memory, and delayed recall. This result held despite the inclusion of the maze score which is a well-validated measure of visuo-spatial memory.  相似文献   
105.
Commercial brewing trials with Zenith hops from the 1982 and 1983 crops have shown that these hops are suitable for producing both ales and lager beers.  相似文献   
106.
响洪甸抽水蓄能电站水下岩塞爆破施工要求高,技术新,难度大.由于施工准备充分,并进行了一系列材料及施工试验,工程进展顺利,排孔造孔、导洞药室开挖、药管与起爆体加工、装药与堵塞、网络施工、充水补气等工程施工质量符合设计要求,岩塞爆破准时成功起爆.  相似文献   
107.
在简要介绍CTS-26型超声探伤仪工作原理及组成的基础上。对其几种典型故障作了具体的分析和处理。  相似文献   
108.
This study examined the efficacy of task analysis training for case managers helping seriously mentally ill patients find roommates and housing. Behavioral objectives and task analysis were used to develop the task-oriented behavioral training program. Case managers were trained to use a checklist for every session with patients, which included the goal of the session, tasks required to accomplish that goal and lists of all the sub-tasks. The results of this study suggest that this methodology: (1) reduced the time required for patients to find roommates and housing; (2) increased the percentage of patients finding housing; and (3) decreased hospitalization rates occurring during the process of looking for roommates and housing.  相似文献   
109.
何广沂  韩治龙 《爆破》1996,13(1):39-43,52
介绍了一种石方开挖新技术--露天石方深孔水压爆破技术。用试验的方法,通过和常规石方爆破进行类比,从而研究了此项新技术在中型孔径小梯段应用条件下的各种爆破参数,并进行了定性和定量分析,得到了一些初步的结论。  相似文献   
110.
This paper proposes an identity-based threshold decryption scheme IB-ThDec and reduces its security to the Bilinear Diffie-Hellman problem. Compared with previous work, this conceals two pairing computations in the ciphertext validity verification procedure. The formal proof of security of this scheme is provided in the random oracle model. Additionally, we show that IB-ThDec can be applied to the threshold key escrow and the mediated cryptosystems.  相似文献   
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