Slow eroding biodegradable multiblock poloxamer copolymers

Biodegradable multiblock poloxamers (BMPs) with gel duration of 8 h to several weeks were prepared by varying their molecular weights from 4000 to 40 000 g mol^?1. The molecular weight of the BMP was controlled by changing the poloxamer to coupling agent ratio. Assuming a micelle packing model of the BMP gel, as in the case of a poloxamer gel, the micelle properties and critical gel concentration of BMPs were investigated on the basis of the scaling concept. The findings suggest that the control of molecular weight by hydrolyzable groups can be a facile approach to optimize the gel properties for biomedical applications. Copyright © 2005 Society of Chemical Industry     

Design of software systems based on axiomatic design

The ability to utilize fully automated flexible manufacturing systems (FMS) or develop reliable computer-integrated manufacturing (CIM) systems will depend on our ability to develop reliable and reusable software for large complex systems on a timely basis. To date, software design has not gone very far beyond the ad hoc trial-and-error stage. Consequently, the development of software is slow, expensive, unreliable, and unmanageable. The purpose of this paper is to provide a scientific basis for designing software. The approach used here is that of axiomatic design, which is based on two design axioms: the Independence Axiom and the Information Axiom. The axiomatic approach is based on the recognition of the following common elements in design: the existence of independent domains (i.e. the consumer domain, the functional domain, the physical domain, and the process domain); the need to map between various domains during the design process; the decomposition of the characteristic vectors (i.e. functional requirements, design parameters, and process variables) in their respective domains; the zig-zagging required between the domains for decomposition; and the need to satisfy the design axioms during the design process. The axiomatic approach discussed in this paper provides decision making tools for software design in addition to systematic means of knowledge and data representation, synthesis and analysis of software, and the construction of the module-junction structure diagram.     

ERCP and CT findings of ectopic drainage of the common bile duct into the duodenal bulb

OBJECTIVE: The purpose of this study was to evaluate ERCP and CT findings of ectopic drainage of the common bile duct into the duodenal bulb. CONCLUSION: Although rare, the diagnosis of ectopic drainage of the common bile duct into the duodenal bulb is important to prevent inadvertent damage during biliary tract or gastric surgery and to clarify the cause of chronic peptic ulcers.     

Effect of the pressure drop rate on cell nucleation in continuous processing of microcellular polymers

Microllular plastics are cellular polymers characterized by cell densities greater than 10⁹ cells/cm³ and cells smaller than 10 μm. One of the critical steps in the continuous production of microcellular plastics is the promotion of high cell nucleation rates in a flowing polymer matrix. These high nucleation rates can be achieved by first forming a polymer/gas solution followed by rapidly decreasing the solubility of gas in the polymer. Since, in the processing range of interest, the gas solubility in the polymer decreases as the pressure decreases, a rapid pressure drop element, consisting of a nozzle, has been employed as a continuous microcellular nucleation device. In this paper, the effects of the pressure drop rate on the nucleation of cells and the cell density are discussed. The experimental results indicate that both the magnitude and the cell density are discussed. The experimental results indicate that both the magnitude and the rate of pressure drop play a strong role in microcellular processing. The pressure phenomenon affects the thermodynamic instability induced in the polymer/gas solution and the competition between cell nucleation and growth.     

Space charge in polyethylene/ionomer blends

Measurements of thermally stimulated currents were made on ionomer/polyethylene blends. The objective of this work was to study space charge formation in these materials. Two ionomers were compared; both ionomers contained methacrylic acid, neutralized by zinc in one and by sodium in the other. A large current peak centered near 60°C was observed in all blends and associated with the motion of space charges injected into the blends during poling. All blends accumulated large negative space charge concentrations. The approach to the equilibrium space charge distribution (negative and spatially uniform in all blends) is much more rapid in the blends containing the sodium ionomer than in the blends containing the zinc ionomer     

ARTIFICIAL INTELLIGENCE CONTROL OF FOOD FREEZER USING ROTATING DISK AIR DISTRIBUTOR FOR UNIFORM FREEZING

A rotating disk air distribution (RDAD) system consisting of a rotating disk with an air supply hole was fabricated to solve the nonuniform freezing problem of a freezer that supplies air through a duct at a fixed location. The RDAD system was installed in a freezer to supply freezing air in various directions by controlling the position of the air supply hole. An equation estimating air velocity in the freezer was developed based on heat balance between a brass block thermocouple (BBT) probe and ambient air stream. The equation was applied to the analysis of airflow patterns developed through the RDAD and the fixed duct system. For control of the RDAD system, a fuzzy matrix was constructed with the measured nodal temperature at 3D locations in the freezer and used to search for the optimum direction of air supply. Uniform cooling was accomplished with the RDAD system using fuzzy and expert algorithms leading to temperature deviation σ=0.666, compared with 0.289 of the fixed air supply system. Cooling rate of model food (BBT) was 1.75 times faster than that of the fixed system.     

Vertex-based inter-frame boundary encoding scheme

The boundary is approximated by a polygon which can be encoded with the smallest number of bits for maximum distortion. The temporal redundancy between two successive frames is efficiently removed with the proposed scheme, resulting in a lower bit rate than the conventional algorithms