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51.
The PVA/PVP, PVA/PVP with 5% and 10% chitosan and PVA/PVP-Iodine fibers were produced via electrospinning technique. Their morphological and chemical characteristics were examined with SEM, TGA, FT-IR, viscometer and four-point probe conductivity measurement apparatus. The addition of chitosan increased the viscosity and the electrical conductivity of the polymer. The increase chitosan contents resulted in the diameters of the fibers smaller than expected. This was attributed to the increase in the viscosity of the solution and the electrical conductivity of the resulting fibers. The DSC results show that iodine was efficiently cross-linked with the polymer, forming an amorphous structure. 相似文献
52.
Juan M. Coronado Javier Soria José Carlos Conesa Ricardo Bellod Cristina Adán Hiroyuki Yamaoka Vittorio Loddo Vincenzo Augugliaro 《Topics in Catalysis》2005,35(3-4):279-286
A continuous photoreactor, working in a total recycle mode and irradiated by a low-pressure Hg lamp, has been used to study
the bactericidal effect of a photocatalyst, formed by TiO2 embedded in SiO2 fibres, on Legionella pneumophila and a consortium of common gram-negative aerobic bacteria: (Escherichia coli, Klebsiella sp., Pseudomona sp. and Proteus sp.) in water. The kinetic modeling of the inactivation process, carried out with the measured values of viable bacteria
concentration at the outlet of photoreactor, evidenced that for each pass inside the photoreactor the ratio between the outlet
and inlet cell concentrations was of order of 0.01 for the inactivation of L. pneumophila. For the other aerobic bacteria, which are usually taken as reference in photocatalytic bacteria inactivation studies, this
ratio was of order of 0.3 for the first hour of illumination, while upon prolonged irradiation (up to 9 h) this ratio increased
to 0.7. Several factors inducing this latter decrease of efficiency are possible, as e.g. competition for photocatalytic attack
between microorganisms and organic compounds released by damaged bacteria or photoinduced alteration of a small fraction of
still viable bacteria making them less interactive with the photocatalyst. The inactivation mechanism normally proposed for
common bacteria involves an initial attack of the photogenerated radicals to the outer membrane; the consequent membrane dispersion
allows the radicals to damage the cytoplasmic membrane. The higher lethality of the photocatalytic method observed towards
Legionella: (in comparison to the other aerobic bacteria) is explained considering that the radicals attack the Legionella secretion system, which is adapted for high virulence and would become activated for and through adhesion to the TiO2 surface. This attack would then be able to inactivate L. pneumophila without dispersing the outer membrane. Apart from this, the water flow through the catalyst fibres can facilitate the bacteria
transport towards the anatase surface, and additionally the generated shear stress may help adhesion, at least for some bacteria
as E. coli, contributing further to improve the photokilling efficiency; both factors may contribute to the efficiency of this photoreactor
configuration. 相似文献
53.
The sex pheromone released by the adult female Tenebrio molitor, 4-methyl-1-nonanol, is well known. In addition, there is evidence that adult males release a pheromone that attracts females.
The purpose of the present study was to isolate and identify male-released pheromone(s). Emissions from virgin adult males
and females were collected on filter paper and extracted with pentane. Extracts were analyzed by gas chromatography-mass spectrometry.
One male-specific compound was detected and identified as (Z)-3-dodecenyl acetate (Z3-12:Ac). In arena bioassays, E3-12:Ac was attractive to females only, at 1 and 10 μg doses. E3-12:Ac
was also attractive to females at a 10-μg dose. The presence of both male and female pheromones, each attracting the opposite
sex, may contribute to maintaining a high-density population of both sexes. 相似文献
54.
Wadman MW van Zadelhoff G Hamberg M Visser T Veldink GA Vliegenthart JF 《Lipids》2005,40(11):1163-1170
Oxylipins are associated with important processes of the fungal life cycle, such as spore formation. Here, we report the formation
of FA metabolites in Agaricus bisporus. Incubation of a crude extract of lamellae with linoleic acid (18∶2) led to the extensive formation of two oxylipins. They
were identified as 8(R)-hydroxy-9Z,12Z-octadecadienoic acid (8-HOD) and 8(R),11(S)-dihydroxy-9Z,12Z-octadecadienoic acid (8,11-diHOD) by using RP-HPLC, GC-MS, IR, GC-MS analysis of diastereomeric derivatives, and 1H NMR and 13C NMR spectroscopy. Neither compound has been reported before in A. bisporus. Oleic (18∶1), α-linolenic (18∶3n−3), and γ-linolenic (18∶3n−6) acids were converted into their 8-hydroxy derivatives as
well, and 18∶3n−3 was further metabolized to its 8,11-diol derivative. Reactions with [U-13C]18∶2 demonstrated that the compounds 8-HOD and 8,11-diHOD were formed from exogenously supplied 18∶2. When [U-13C]8-HOD was supplied, it was not converted into 8,11-diHOD, indicating that it was not an intermediate in the formation of
8,11-diHOD. When a crude extract of A. bisporus was incubated under an atmosphere of 16O2/18O2, the two hydroxyl groups of 8,11-diHOD contained either two 18O atoms or two 16O atoms. Species that contained one of each isotope could not be detected. We propose that the formation of the 8,11-dihydroxy
compounds occurs through either an 8,11-endoperoxy, an 8-peroxo free radical, or an 8-hydroperoxy intermediate. In the latter
case, the reaction should be catalyzed by dioxygenase with novel specificity. 相似文献
55.
A.-M. Hilmen E. Bergene O.A. Lindvg D. Schanke S. Eri A. Holmen 《Catalysis Today》2005,105(3-4):357-2
Monolithic catalysts made of cordierite and γ-Al2O3 have been prepared and tested for the Fischer–Tropsch (FT) synthesis. When operated without oil circulation, washcoated cordierite monoliths have previously been shown to be as active and selective as the corresponding powder catalyst provided that the monoliths have low washcoat loadings. Two-phase operation, i.e. with oil/product circulation during reaction, resulted in improved heat removal and temperature control, in lower apparent activity and faster deactivation, but the C5+ selectivity was equal to or even better than without oil circulation. The lower apparent activities obtained with oil circulation seem to be a combination of catalyst deactivation and flow-related problems in the present experimental set-up. 相似文献
56.
LED光色度测试中存在的问题探讨 总被引:4,自引:1,他引:4
在分析发光二极管(LED)光色特性的特殊性和复杂性的基础上,试着寻求得到更加准确数据的测试方法。封装、温度、探测器、测量定律等都可对LED参数的测量结果产生重大的影响,只有减小各项误差后才可以得到接近真实的测量结果。 相似文献
57.
H. W. Brinks V. A. Yartys B. C. Hauback H. Fjellvg B. Ouladdiaf 《Journal of Alloys and Compounds》2002,340(1-2):62-66
TbNiSiD1.78 has been studied by powder neutron diffraction below 100 K. The compound takes the hexagonal room temperature structure at 100 and 50 K (P63/mmc). At 2 K, below the antiferromagnetic ordering temperature of 10 K, there is a small orthorhombic distortion of the lattice. The refined unit-cell dimensions at 2 K (space group Pnma) are a=7.9505(2), b=4.02502(14), c=6.9823(2) Å. The magnetic moments of Tb are 8.71(6) μB, and are ordered antiferromagnetically along a. 相似文献
58.
Jarosaw Widelski Simon Vlad Luca Adrianna Skiba Monika Macig Barbara Budzyska Laurence Marcourt Jean-Luc Wolfender Krystyna Skalicka-Wo
niak 《International journal of molecular sciences》2021,22(4)
Different types of anxiety disorders have become the number one mental health issue in developed countries. The search for new, safer and effective drug-like molecules among naturally derived substances faces two difficulties: an efficient method of isolation compounds with a high-purity and high-throughput animal model for activity assay. Thus, the aim of the present study was to isolate by liquid–liquid chromatography high-purity rare coumarins from the fruits of Seseli devenyense Simonk. and evaluate their anxiolytic effect (defined as reversed thimotaxis) using a 5-days post-fertilization (dpf) Danio rerio larvae model. Liquid–liquid chromatography enabled the isolation of one simple hydroxycoumarin (devenyol) and four pyranocoumarins (cis-khellactone, d-laserpitin, isolaserpitin and octanoyllomatin). The anxiolytic effect was defined as a decrease in the time spent in the boundaries of the living space (also described as reversed thigmotaxis). Our results show that all isolated courmarins exerted a significant influence on the anxiety behavior (anxiolytic activity) in the zebrafish larvae model. According to our knowledge, this is the first report of anxiolytic activity of pyranocoumarins and devenyol. 相似文献
59.
60.
Alexandra Kiss Csaba Csikos Zsolt Regdon Zsuzsanna Polgr Lszl Virg Csaba Hegeds 《International journal of molecular sciences》2021,22(16)
Osteosarcoma is a frequent and extremely aggressive type of pediatric cancer. New therapeutic approaches are needed to improve the overall survival of osteosarcoma patients. Our previous results suggest that NMNAT1, a key enzyme in nuclear NAD+ synthesis, facilitates the survival of cisplatin-treated osteosarcoma cells. A high-throughput cytotoxicity screening was performed to identify novel pathways or compounds linked to the cancer-promoting role of NMNAT1. Nine compounds caused higher toxicity in the NMNAT1 KO U2OS cells compared to their wild type counterparts, and actinomycin D (ActD) was the most potent. ActD-treatment of NMNAT1 KO cells increased caspase activity and secondary necrosis. The reduced NAD+ content in NMNAT1 KO cells was further decreased by ActD, which partially inhibited NAD+-dependent enzymes, including the DNA nick sensor enzyme PARP1 and the NAD+-dependent deacetylase SIRT1. Impaired PARP1 activity increased DNA damage in ActD-treated NMNAT1 knockout cells, while SIRT1 impairment increased acetylation of the p53 protein, causing the upregulation of pro-apoptotic proteins (NOXA, BAX). Proliferation was decreased through both PARP- and SIRT-dependent pathways. On the one hand, PARP inhibitors sensitized wild type but not NMNAT1 KO cells to ActD-induced anti-clonogenic effects; on the other hand, over-acetylated p53 induced the expression of the anti-proliferative p21 protein leading to cell cycle arrest. Based on our results, NMNAT1 acts as a survival factor in ActD-treated osteosarcoma cells. By inhibiting both PARP1- and SIRT1-dependent cellular pathways, NMNAT1 inhibition can be a promising new tool in osteosarcoma chemotherapy. 相似文献