A multivariable control scheme in a two-stage anaerobic digestion system described by partial differential equations

This paper deals with the design and application of a nonlinear multivariable controller in an anaerobic digestion system (AD) carried out in two interconnected fixed bed bioreactors. The proposed control scheme is derived from a mathematical model of the AD system described by a set of partial differential equations and consists of an estimator and two nonlinear control laws. The first law is developed to regulate the volatile fatty acids in the first bioreactor while the second aims at maintaining the chemical oxygen demand at predetermined set-points in the second bioreactor. The performance of the control algorithm is evaluated via numerical simulations in the face of load disturbances, parameter kinetic uncertainties and set-point changes. Stability and convergence properties of the proposed control scheme are also addressed in this paper.     

Mobile crowdsensing with mobile agents

We introduce mobile agents for mobile crowdsensing. Crowdsensing campaigns are designed through different roles that are implemented as mobile agents. The role-based tasks of mobile agents include collecting data, analyzing data and sharing data in the campaign. Mobile agents execute and control the campaign autonomously as a multi-agent system and migrate in the opportunistic network of participants’ devices. Mobile agents take into account the available resources in the devices and match participants’ privacy requirements to the campaign requirements. Sharing of task results in real-time facilitates cooperation towards the campaign goal while maintaining a selected global measure, such as energy efficiency. We discuss current challenges in crowdsensing and propose mobile agent based solutions for campaign execution and monitoring, addressing data collection and participant-related issues. We present a software framework for mobile agents-based crowdsensing that is seamlessly integrated into the Web. A set of simulations are conducted to compare mobile agent-based campaigns with existing crowdsensing approaches. We implemented and evaluated a small-scale real-world mobile agent based campaign for pedestrian flock detection. The simulation and evaluation results show that mobile agent based campaigns produce comparable results with less energy consumption when the number of agents is relatively small and enables in-network data processing with sharing of data and task results with insignificant overhead.     

A note on the security of PAP

In this letter, we analyze the security of an RFID authentication protocol proposed by Liu and Bailey [1], called privacy and authentication protocol (PAP). We present two traceability attacks and an impersonation attack.     

Applying intelligent agents and semantic web services in eGovernment environments

The increasing volume of eGovernment‐related services is demanding new approaches for service integration and interoperability in this domain. Semantic web (SW) technologies and applications can leverage the potential of eGovernment service integration and discovery, thus tackling the problems of semantic heterogeneity characterizing eGovernment information sources and the different levels of interoperability. eGovernment services will therefore be semantically described in the foreseeable future. In an environment with semantically annotated services, software agents are essential as the entities responsible for exploiting the semantic content in order to automate some tasks, and so enhance the user's experience. In this paper, we present a framework that provides a seamless integration of semantic web services and intelligent agents technologies by making use of ontologies to facilitate their interoperation. The proposed framework can assist in the development of powerful and flexible distributed systems in complex, dynamic, heterogeneous, unpredictable and open environments. Our approach is backed up by a proof‐of‐concept implementation, where the breakthrough of integrating disparate eGovernment services has been tested.     

Interactive Ray Tracing of Large Models Using Voxel Hierarchies

We propose an efficient approach for interactive visualization of massive models with CPU ray tracing. A voxel‐based hierarchical level‐of‐detail (LOD) framework is employed to minimize rendering time and required system memory. In a pre‐processing phase, a compressed out‐of‐core data structure is constructed, which contains the original primitives of the model and the LOD voxels, organized into a kd‐tree. During rendering, data is loaded asynchronously to ensure a smooth inspection of the model regardless of the available I/O bandwidth. With our technique, we are able to explore data sets consisting of hundreds of millions of triangles in real‐time on a desktop PC with a quad‐core CPU.     

On the asymmetrical dependence of the threshold pressure of infiltration on the wettability of the porous solid by the infiltrating liquid

A general equation has been derived for the threshold pressure of infiltration of liquids into porous solids. From this equation all the known equations for the threshold pressure can be obtained, using different assumptions on the morphology of the porous solid and on the way how the liquid infiltrates the solid. Particularly, the Young-Laplace equation, the Carman-equation, and the modification of the Carman equation, suggested by White and later by Mortensen and Cornie have been reproduced as particular cases of the general equation. A new particular solution of this general equation is also suggested, taking into account that the original solid/gas interface inside the porous body is not fully replaced by the solid/liquid interface during infiltration, especially for the case of non-wetting liquids. The new, general equation consists of three semi-empirical parameters, which should be found experimentally for a given type of morphology of the porous solid and for the given ratio of the surface tension to the density of the infiltrating liquid metal. The new equation provides a value of the threshold contact angle to be between 65.5° and 90°, depending on the morphology of the porous solid. Consequently, the threshold pressure appears to be an asymmetrical function of the contact angle. Based on the new equation, the practical constancy of the threshold pressure is predicted in the interval of the contact angles between 120° and 180°.     

Can porous polymeric scaffolds be functionalized by stem cells leading to osteogenic differentiation? A systematic review of in vitro studies

The aim of this study was to analyze the influence of nanoporous structure of polymeric biomaterials on the in vitro osteogenic induction of human stem cells. An electronic search in three databases (MEDLINE, SCOPUS, and Web of Science) was performed for articles that were published before May 2018. In vitro studies were included if they met the following criteria: (1) the use of polymeric scaffolds (natural or synthetic); (2) the co-culture of human stem cells with the scaffold; and (3) cell viability, proliferation, and osteogenic differentiation assays. The main characteristics of the published studies were summarized, and a quality assessment tool was used to analyze methodological features. Eighty-eight potential articles were firstly retrieved. Thirteen were eligible for qualitative analysis. Only three studies characterized cell stemness. Nanostructure of the scaffolds showed a significant influence on viability, proliferation, and osteogenic differentiation of human stem cells. Combination of porosity between 72 and 93% and a large range diameter between 50 and 224 μm resulted in more remarkable cellular proliferation and differentiation. Porous polymeric scaffolds can be functionalized by stem cells leading to osteogenic induction. High standards of laboratory practice and accurate methodological reporting are essential for the credibility of the results.     

Genetics and Epigenetics of Spontaneous Intracerebral Hemorrhage

Intracerebral hemorrhage (ICH) is a complex and heterogeneous disease, and there is no effective treatment. Spontaneous ICH represents the final manifestation of different types of cerebral small vessel disease, usually categorized as: lobar (mostly related to cerebral amyloid angiopathy) and nonlobar (hypertension-related vasculopathy) ICH. Accurate phenotyping aims to reflect these biological differences in the underlying mechanisms and has been demonstrated to be crucial to the success of genetic studies in this field. This review summarizes how current knowledge on genetics and epigenetics of this devastating stroke subtype are contributing to improve the understanding of ICH pathophysiology and their potential role in developing therapeutic strategies.