Meniere's disease. A neuropsychological study

A neuro-psychological study is described comprising 19 patients with Meniere's Disease who were participating in an experimental lithium therapy programme. The patients evidenced an organic dysfunction which is not entirely periphearl. The interpretation of the results are not incompatible with an attempt to reconcile neuro-psychological and psycho-somatic viewpoints regarding etiological aspects of Meniere's Disease. An evaluation of the lithium effect was performed.     

Diagnosis and management of colovesical fistulas

Diagnosis and management may present difficult problems in patients with colovesical fistulas. Symptoms in the urinary tract are most common, and cystoscopy, and cystography are the most valuable diagnostic procedures. It may not always be possible to demonstrate the fistula by diagnostic tests, and a high index of suspicion should be maintained in patients with inflammatory or neoplastic disease of the rectosigmoid area or bladder with recurrent cystitis. Definitive treatment should include resection of the fistula and diseased segment of the intestine. Both one stage and multistage procedures have their place in the treatment of this condition. There are specific criteria for success for a one stage procedure.     

Molecular weight changes in polyacrylates on ultraviolet irradiation

Films of poly(methyl acrylate), poly(ethyl acrylate), and poly(n-butyl acrylate) were irradiated by means of a high-pressure mercury lamp in oxygen and nitrogen atmospheres, and the molecular weight changes accompanying degradation were studied as a function of radiation dose. Crosslinked material was formed in all cases though less crosslinking occurred in oxygen than in nitrogen atmospheres. Scission was the major reaction in the photo-oxidation of poly(ethyl acrylate), and this was explained in terms of acetal formation. In a nitrogen atmosphere, the proportion of units fractured to the proportion of units crosslinked per unit radiation dose was constant for the three polymers. Gel permeation chromatographic studies showed the accumulation of low molecular weight fragments on prolonged photolysis, and this was explained in terms of a chain reaction mechanism.     

Determinants and validity of self-estimates of abilities and self-concept measures.

How accurate are self-estimates of cognitive abilities? An investigation of self-estimates of verbal, math, and spatial abilities is reported with a battery of parallel objective tests of abilities. Self-estimates were obtained prior to and after objective ability testing (without test feedback) in order to examine whether self-estimates change after direct objective testing experience. Self-estimates showed small to large effect-size correlations with objective tests--larger for math and smaller for verbal. The construct space of self-estimates of abilities was explored in the context of self-concept, self-esteem, self-efficacy, personality, interests, motivational traits, and trait complexes. Self-efficacy and self-esteem variables showed the highest correlations with self-estimates of abilities. In general, trait complexes showed the highest correlations with verbal ability self-estimates and the lowest correlations with math ability self-estimates. Results are discussed in relation to the principle of aggregation, the influences of self-evaluative judgments, and uses for self-estimates of abilities measures. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Further explorations of perceptual speed abilities in the context of assessment methods, cognitive abilities, and individual differences during skill acquisition.

Measures of perceptual speed ability have been shown to be an important part of assessment batteries for predicting performance on tasks and jobs that require a high level of speed and accuracy. However, traditional measures of perceptual speed ability sometimes have limited cost-effectiveness because of the requirements for administration and scoring of paper-and-pencil tests. There have also been concerns about the validity of previous computer approaches to administering perceptual speed tests (e.g., see Mead & Drasgow, 1993). The authors developed two sets of computerized perceptual speed tests, with touch-sensitive monitors, that were designed to parallel several paper-and-pencil tests. The reliability and validity of the tests were explored across three empirical studies (N = 167, 160, and 117, respectively). The final study included two criterion tasks with 4.67 and 10 hours of time-on-task practice, respectively. Results indicated that these new measures provide both high levels of reliability and substantial validity for performance on the two skill-learning tasks. Implications for research and application for computerized perceptual speed tests are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Progressive systemic sclerosis: intrathecal pain management

PURPOSE: To determine if lucanthone crossed the blood-brain barrier in experimental animals; and to determine accelerated tumor regression of human brain metastases treated jointly with lucanthone and whole brain radiation. METHODS AND MATERIALS: The organ distribution of 3H lucanthone in mice and 125I lucanthone in rats was determined to learn if lucanthone crossed the blood-brain barrier. Size determinations were made of patients' brain metastases from magnetic resonance images or by computed tomography before and after treatment with 30 Gy whole brain radiation alone or with lucanthone. RESULTS: The time course of lucanthone's distribution in brain was identical to that in muscle and heart after intraperitoneal or intravenous administration in experimental animals. Lucanthone, therefore, readily crossed the blood-brain barrier in experimental animals. CONCLUSION: Compared with radiation alone, the tumor regression in patients with brain metastases treated with lucanthone and radiation was accelerated, approaching significance using a permutation test at p = 0.0536.     

Gender and age differences in employee decisions about new technology: an extension to the theory of planned behavior

This research extends the theory of planned behavior by incorporating gender and age as moderators of user perceptions and individual adoption and sustained use of technology in the workplace. Individual reactions and technology use behavior were studied over a six-month period among 342 workers being introduced to a new software technology application. While previous studies in the literature have reported gender or age differences separately, the pattern of results from the study reported here indicated that gender effects in individual adoption and use of technology differed based on age. Specifically, gender differences in technology perceptions became more pronounced among older workers, but a unisex pattern of results emerged among younger workers. The theory and empirical results are also discussed in relation to the widely employed technology acceptance model. The results from this study suggest that old stereotypes that portray "technology" as a male-oriented domain may be disappearing; particularly among younger workers. In light of these findings, theoretical implications for researchers and practical suggestions for managers are discussed.