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91.
Fatigue is a serious issue for the rail industry, increasing inefficiency and accident risk. The performance of 20 train drivers in a rail simulator was investigated at low, moderate and high fatigue levels. Psychomotor vigilance (PVT), self-rated performance and subjective alertness were also assessed. Alertness, PVT reaction times, extreme speed violations (>25% above the limit) and penalty brake applications increased with increasing fatigue level. In contrast, fuel use, draft (stretch) forces and braking errors were highest at moderate fatigue levels. Thus, at high fatigue levels, errors involving a failure to act (errors of omission) increased, whereas incorrect responses (errors of commission) decreased. The differential effect of fatigue on error types can be explained through a cognitive disengagement with the virtual train at high fatigue levels. Interaction with the train reduced dramatically, and accident risk increased. Awareness of fatigue-related performance changes was moderate at best. These findings are of operational concern. 相似文献
92.
We prove new lower bounds for learning intersections of halfspaces, one of the most important concept classes in computational learning theory. Our main result is that any statistical-query algorithm for learning the intersection of $\sqrt{n}$ halfspaces in n dimensions must make $2^{\varOmega (\sqrt{n})}$ queries. This is the first non-trivial lower bound on the statistical query dimension for this concept class (the previous best lower bound was n Ω(log?n)). Our lower bound holds even for intersections of low-weight halfspaces. In the latter case, it is nearly tight. We also show that the intersection of two majorities (low-weight halfspaces) cannot be computed by a polynomial threshold function (PTF) with fewer than n Ω(log?n/log?log?n) monomials. This is the first super-polynomial lower bound on the PTF length of this concept class, and is nearly optimal. For intersections of k=ω(log?n) low-weight halfspaces, we improve our lower bound to $\min\{2^{\varOmega (\sqrt{n})},n^{\varOmega (k/\log k)}\},$ which too is nearly optimal. As a consequence, intersections of even two halfspaces are not computable by polynomial-weight PTFs, the most expressive class of functions known to be efficiently learnable via Jackson’s Harmonic Sieve algorithm. Finally, we report our progress on the weak learnability of intersections of halfspaces under the uniform distribution. 相似文献
93.
Olle EW Deogracias MP Messamore JE McClintock SD Barron AG Anderson TD Johnson KJ 《Proteomics. Clinical applications》2007,1(10):1212-1220
Wegener's Granulomatosis (WG) is an idiopathic granulomatosis autoimmune vasculitis that primarily affects small vessels and is associated with glomerulonephritis and pulmonary granulomatous vasculitis. Anti‐neutrophil cytoplasmic auto‐antibodies (cANCA) against proteinase‐3 are used to identify WG, but ANCA titers are not present in some patients with the localized disease. The objective of this study was to develop an antibody array to help identify protein expression patterns in serum from patients with WG as compared to normals. The arrays were tested for limits of detection, background, and cross reactivity using standard proteins. The arrays were hybridized with either normal patient serum (n = 30) or with serum samples from a population of WG patients (n = 26) that were age and sex matched. Data analysis and curve fitting of the standard dilution series calculated r2 values and determined a sensitivity of <50 pg/mL for the majority of proteins. A total of 24 proteins were assessed. Several statistically significant increases (p<0.05) were seen in the expression of: angiotensin converting enzyme‐I, IFN‐γ, IL‐8, s‐ICAM‐1 and s‐VCAM in WG patients as compared to controls. Utilizing the antibody microarray technology has led to the identification of potential biomarkers of vascular injury in the serum of WG patients. 相似文献
94.
Balancing systematic and flexible exploration of social networks 总被引:1,自引:0,他引:1
Social network analysis (SNA) has emerged as a powerful method for understanding the importance of relationships in networks. However, interactive exploration of networks is currently challenging because: (1) it is difficult to find patterns and comprehend the structure of networks with many nodes and links, and (2) current systems are often a medley of statistical methods and overwhelming visual output which leaves many analysts uncertain about how to explore in an orderly manner. This results in exploration that is largely opportunistic. Our contributions are techniques to help structural analysts understand social networks more effectively. We present SocialAction, a system that uses attribute ranking and coordinated views to help users systematically examine numerous SNA measures. Users can (1) flexibly iterate through visualizations of measures to gain an overview, filter nodes, and find outliers, (2) aggregate networks using link structure, find cohesive subgroups, and focus on communities of interest, and (3) untangle networks by viewing different link types separately, or find patterns across different link types using a matrix overview. For each operation, a stable node layout is maintained in the network visualization so users can make comparisons. SocialAction offers analysts a strategy beyond opportunism, as it provides systematic, yet flexible, techniques for exploring social networks 相似文献
95.
The confused world of sulfate attack on concrete 总被引:13,自引:0,他引:13
Adam Neville 《Cement and Concrete Research》2004,34(8):1275-1296
External sulfate attack is not completely understood. Part I identifies the issues involved, pointing out disagreements, and distinguishes between the mere occurrence of chemical reactions of sulfates with hydrated cement paste and the damage or deterioration of concrete; only the latter are taken to represent sulfate attack. Furthermore, sulfate attack is defined as deleterious action involving sulfate ions; if the reaction is physical, then, it is physical sulfate attack that takes place. The discussion of the two forms of sulfate attack leads to a recommendation for distinct nomenclature. Sulfate attack on concrete structures in service is not widespread, and the amount of laboratory-based research seems to be disproportionately large. The mechanisms of attack by different sulfates—sodium, calcium, and magnesium—are discussed, including the issue of topochemical and through-solution reactions. The specific aspects of the action of magnesium sulfate are discussed, and the differences between laboratory conditions and field exposure are pointed out.Part II discusses the progress of sulfate attack and its manifestations. This is followed by a discussion of making sulfate-resisting concrete. One of the measures is to use Type V cement, and this topic is extensively discussed. Likewise, the influence of w/c on sulfate resistance is considered. The two parameters are not independent of one another. Moreover, the cation in the sulfate salt has a strong bearing on the efficiency of the Type V cement. Recent interpretations of the Bureau of Reclamation tests, both long term and accelerated, are evaluated, and it appears that they need reworking.Part III reviews the standards and guides for the classification of the severity of exposure of structures to sulfates and points out the lack of calibration of the various classes of exposure. A particular problem is the classification of soils because much depends on the extraction ratio of sulfate in the soil: there is a need for a standardized approach. Taking soil samples is discussed, with particular reference to interpreting highly variable contents of sulfates. The consequences of disturbed drainage of the soil adjacent to foundations and of excessive irrigation, coupled with the use of fertilizer, are described. Whether concrete has undergone sulfate attack can be established by determining the change in the compressive strength since the time of placing the concrete. The rejection of this method and the reliance on determining the tensile strength of concrete because of “layered damage” are erroneous. Scanning electron microscopy (SEM) should not be the primary, and certainly not the first, method of determining whether sulfate attack has occurred. Mathematical modeling will be of help in the future but, at present, cannot provide guidance on the sulfate resistance of concrete in structures.Part IV presents conclusions and an overview of the situation, with consideration of future improvements. Appendix A contains the classification of exposure to sulfate given by various codes and guides. 相似文献
96.
Pawe?czyk A 《Water science and technology》2012,66(3):666-672
This paper presents results of analyses of water in the river Ma?a Panew in South West Poland flowing through a rural area with some chemical industry developed. The aims of the work were to investigate the pollutants level in the river, compare the obtained results with obligatory drinking water standards and determine possible health effects when using the river as a source for drinking water production. Attention was given to nitrogen compounds as nitrate(V) ions (NO(3-)) and nitrite(III) ions (NO(2-)), mostly of anthropogenic origin, were detected in the monitored water. The average concentrations of NO(3-) and NO(2-) were 3.54 and 0.286 mg/dm(3), respectively. The chances for non-carcinogenic effects, namely methemoglobinemia, resulting from possible exposure to the examined chemicals were determined based on the analytical and toxicological data. As infants are the sub-population most susceptible to nitrate-induced methemoglobinemia, the assessment was limited to children aged 0-3 years. The determined values expressed by hazard quotient (HQ) and hazard index (HI) indicate that the water pollutants and their concentrations do not exceed unity; however, in the case of infants, the other nitrate sources should be controlled. 相似文献
97.
Carabalona R Grossi F Tessadri A Castiglioni P Caracciolo A de Munari I 《Ergonomics》2012,55(5):552-563
Brain-computer interface (BCI) systems aim to enable interaction with other people and the environment without muscular activation by the exploitation of changes in brain signals due to the execution of cognitive tasks. In this context, the visual P300 potential appears suited to control smart homes through BCI spellers. The aim of this work is to evaluate whether the widely used character-speller is more sustainable than an icon-based one, designed to operate smart home environment or to communicate moods and needs. Nine subjects with neurodegenerative diseases and no BCI experience used both speller types in a real smart home environment. User experience during BCI tasks was evaluated recording concurrent physiological signals. Usability was assessed for each speller type immediately after use. Classification accuracy was lower for the icon-speller, which was also more attention demanding. However, in subjective evaluations, the effect of a real feedback partially counterbalanced the difficulty in BCI use. PRACTITIONER SUMMARY: Since inclusive BCIs require to consider interface sustainability, we evaluated different ergonomic aspects of the interaction of disabled users with a character-speller (goal: word spelling) and an icon-speller (goal: operating a real smart home). We found the first one as more sustainable in terms of accuracy and cognitive effort. 相似文献
98.
Mihajlo Grbovic Weichang Li Peng Xu Adam K. Usadi Limin Song Slobodan Vucetic 《Journal of Process Control》2012,22(4):738-750
This paper proposes an approach for decentralized fault detection and diagnosis in process monitoring sensor networks. The sensor network is decomposed into multiple, potentially overlapping, blocks using the Sparse Principal Component Analysis algorithm. Local predictions are generated at each block using Support Vector Machine classifiers. The local predictions are then fused via a Maximum Entropy algorithm. Empirical studies on the benchmark Tennessee Eastman Process data demonstrated that the proposed decentralized approach achieves accuracy comparable to that of the fully centralized approach, while offering benefits in terms of fault tolerance, reusability, and scalability. 相似文献
99.
Uday B. Pal Scott A. MacDonald David W. Woolley Adam C. Powell 《Metallurgical and Materials Transactions B》2005,36(2):209-218
Two techniques are described for the enhancement of the kinetics of reduction of iron oxide from slags by carbon in molten
iron. Laboratory experiments have shown that the rate of iron oxide reduction by carbon-saturated iron can be increased by
5 to 10 times when the reaction is carried out under a reduced-pressure atmosphere. This effect is thought to be the result
of the increased volumetric gas evolution through the slag layer and the associated increase in slag stirring. A model is
presented, which relates the mass-transfer coefficient for ferrous ions in the slag to its stirring that is controlled by
varying the ambient pressure. Additional laboratory experiments examined the electrochemical nature of iron oxide reduction
from slag by carbon in liquid iron. Results indicate that the reduction of iron oxide from slag is increased in the presence
of an applied electric field. The external circuit allows for the separation of the half-cell reactions associated with iron
oxide reduction and decarburization and increases the reaction area available for the individual reactions. These results
have significant implications for several important slag metal reactions, which occur during ironmaking and steelmaking operations. 相似文献
100.
Liu Grace T.; Ferguson Adam R.; Crown Eric D.; Bopp Anne C.; Miranda Rajesh C.; Grau James W. 《Canadian Metallurgical Quarterly》2005,119(2):538
Following spinal transection of the upper thoracic spinal cord, male Sprague-Dawley rats given legshock whenever a hindlimb is extended learn to maintain the leg in a flexed position. The region of the cord that mediates this instrumental learning was isolated using neuroanatomical tracing, localized infusion of lidocaine, and surgical transections. DiI and Fluoro-Gold microinjection at the site of shock application labeled motor neuron bodies of lamina IX in the lower lumbar region. Local application of the Na++ channel blocker lidocaine disrupted learning when it was applied over a region extending from the lower lumbar (L3) to upper sacral (S2) cord. The drug had no effect rostral or caudal to this region. Surgical transections as low as L4 had no effect on learning. Learning also survived a dual transection at L4 and S3, but not L4 and S2. The results suggest that the essential neural circuit lies between L4 and S3. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献