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排序方式: 共有510条查询结果,搜索用时 15 毫秒
101.
Dr. Laura Drummond Parab J. Haque Dr. Binbin Gu Julia S. Jung Dr. Hendrik Schewe Prof. Dr. Jeroen S. Dickschat Dr. Markus Buchhaupt 《Chembiochem : a European journal of chemical biology》2022,23(14):e202200091
The natural substance class of terpenoids covers an extremely wide range of different structures, although their building block repertoire is limited to the C5 compounds DMAPP and IPP. This study aims at the characterization of methyltransferases (MTases) that modify these terpene precursors and the demonstration of their suitability for biotechnological purposes. All seven enzymes tested accepted IPP as substrate and altogether five C6 compounds and six C7 compounds were formed within the reactions. A high selectivity for the deprotonation site as well as high stereoselectivity could be observed for most of the biocatalysts. Only the enzyme from Micromonospora humi also accepted DMAPP as substrate, converting it into (2R)-2-methyl-IPP in vitro. In vivo studies demonstrated the production of a C8 compound and a hydride shift step within the MTase-catalyzed reaction. Our study presents IPP/DMAPP MTases with very different catalytic properties, which provide biosynthetic access to many novel terpene-derived structures. 相似文献
102.
Improved voltage tracking of autonomous microgrid technology using a combined resonant controller with lead-lag compensator adopting negative imaginary theorem
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Md. Yah-Ya Ul Haque Md. Rashidul Islam Tanvir Ahme Md. Rafiqul Islam Sheikh 《电力系统保护与控制》2022,7(1):149-164
Growing application of distributed generation units at remote places has led to the evolution of microgrid (MG) technology. When an MG system functions independently, i.e., in autonomous mode, unpredictable loads and uncertainties emerge throughout the system. To obtain stable and flexible operation of an autonomous MG, a rigid control mechanism is needed. In this paper, a robust high-performance controller is introduced to improve the performance of voltage tracking of an MG system and to eliminate stability problems. A combination of a resonant controller and a lead-lag compensator in a positive position feedback path is designed, one which obeys the negative imaginary (NI) theorem, for both single-phase and three-phase autonomous MG systems. The controller has excellent tracking performance. This is investigated through considering various uncertainties with different load dynamics. The feasibility and effectiveness of the controller are also determined with a comparative analysis with some well-known controllers, such as linear quadratic regulator, model predictive and NI approached resonant controllers. This confirms the superiority of the designed controller. 相似文献
103.
Vancha Harish Effi Haque Magdalena
miech Hiroaki Taniguchi Sarah Jamieson Devesh Tewari Anupam Bishayee 《International journal of molecular sciences》2021,22(9)
Xanthohumol (XH) is an important prenylated flavonoid that is found within the inflorescence of Humulus lupulus L. (Hop plant). XH is an important ingredient in beer and is considered a significant bioactive agent due to its diverse medicinal applications, which include anti-inflammatory, antimicrobial, antioxidant, immunomodulatory, antiviral, antifungal, antigenotoxic, antiangiogenic, and antimalarial effects as well as strong anticancer activity towards various types of cancer cells. XH acts as a wide ranging chemopreventive and anticancer agent, and its isomer, 8-prenylnaringenin, is a phytoestrogen with strong estrogenic activity. The present review focuses on the bioactivity of XH on various types of cancers and its pharmacokinetics. In this paper, we first highlight, in brief, the history and use of hops and then the chemistry and structure–activity relationship of XH. Lastly, we focus on its prominent effects and mechanisms of action on various cancers and its possible use in cancer prevention and treatment. Considering the limited number of available reviews on this subject, our goal is to provide a complete and detailed understanding of the anticancer effects of XH against different cancers. 相似文献
104.
M.Ahsanul Haque A.Bakar Sulong L.Kee Shyuan E.Herianto Majlan T. Husaini R.Emilia Rosli 《International Journal of Hydrogen Energy》2021,46(5):4339-4353
In this study, the polymer/MWCNT nanocomposites were synthesized from the pristine MWCNT and polymer binders using functionalization with solution processing methods. The synthesized polymer/MWCNT nanocomposites exhibited high specific surface areas than the pristine MWCNT. The MWCNT/Nafion nanocomposite attributed to the maximum peak current at 5.795 × 10?5 (A) while the peak current of MWCNT/PBI was obtained at 3.662 × 10?5 (A). Moreover, polymer/MWCNT based electrocatalysts performed better electrochemical activity because of polymers binders can assist electrochemical interaction using the high surface areas of the catalyst supporting material. Also, the MEAs fabricated using the hot pressing method, while the acid doped PBI membrane sandwiched between the electrodes. The fabricated MEAs were successfully demonstrated in a single cell and found capable of measuring a maximum power density of 112.10 mW/cm2 under 150 °C temperature. In conclusion, the synthesized catalyst-supporting materials enhanced the electrochemical activity and catalyst stability which fulfilling the main objective of this study. 相似文献
105.
106.
Aminul Islam Monoranjan Debnath Rony Mahmudul Islam Emdadul Haque Chowdhury Mohammad Nasim Hasan 《亚洲传热研究》2021,50(3):2339-2361
The present study numerically explores the mixed convection phenomena in a differentially heated ventilated square cavity with active flow modulation via a rotating plate. Forced convection flow in the cavity is attained by maintaining external fluid flow through an opening at the bottom of the left cavity wall while leaving it through another opening at the right cavity wall. A counter-clockwise rotating plate at the center of the cavity acts as an active flow modulator. Moving mesh approach is used for the rotation of the plate and the numerical solution is achieved using arbitrary Lagrangian-Eulerian finite element formulation with a quadrilateral discretization scheme. Transient parametric simulations have been performed for various frequency of the rotating plate for a fixed Reynolds number (Re) of 100 based on maximum inlet flow velocity while the Richardson number (Ri) is maintained at unity. Heat transfer performance has been evaluated in terms of spatially averaged Nusselt number and time-averaged Nusselt number along the heated wall. Power spectrum analysis in the frequency domain obtained from the fast Fourier transform analysis indicates that thermal frequency and plate frequency start to deviate from each other at higher values of velocity ratio (>4). 相似文献
107.
108.
M. Abdullah M.U. Akhtar T.N. Pasha J.A. Bhatti Z. Ali M. Saadullah M.N. Haque 《Journal of dairy science》2019,102(4):3000-3009
The effects of feeding rumen-inert fat sources on production responses of lactating dairy cows have been well reported but less thoroughly described in lactating dairy buffalo. The objective of this study was to investigate the effect of oil and 2 different rumen-inert fat sources on dry matter intake, milk yield, milk composition, and milk fatty acid (FA) profile in Nili Ravi buffalo. Twelve multiparous mid-lactating Nili Ravi buffaloes received 4 treatments in a 4 × 4 Latin square design with a period length of 21 d. The treatments were (1) the basal diet without supplementation of oil or fats (CTRL), (2) the basal diet supplemented with canola oil (CO), (3) the basal diet supplemented with calcium salts of palm FA (Ca-FA), and (4) the basal diet supplemented with high palmitic acid (PA). Dry matter intake was decreased by 4.4% in the CO compared with Ca-FA and PA. Milk yield and milk fat yield were increased by 7.8 and 14.3%, respectively, in CO, Ca-FA, and PA compared with the CTRL. Milk fat content increased by 7.5%, whereas milk fat yield tended to increase with the supplementation of Ca-FA and PA compared with CO. No effect on milk yield and milk composition was observed in Ca-FA versus PA treatments. The yield of medium-chain FA was increased by Ca-FA and PA versus CO. The CO treatment increased the yield of long-chain FA compared with Ca-FA and PA treatments. Plasma glucose level was higher in CO, Ca-FA, and PA compared with the CTRL. In conclusion, feeding rumen-inert fats in the lactating buffalo diet proved to be a useful strategy to increase the 3.5% fat-corrected milk yield due to the higher milk fat content in this study. 相似文献
109.
110.
All grades of carbon black contain large amounts of unpaired electrons and organic functional groups. Polymerization reaction is possibly initiated by the unpaired electrons on the surface; the functional groups have promotional effect on the initiation process. All the properties like texture, geometry, surface area, pH of the aqueous slurry, ash content, and elemental composition have effects on the polymerization reaction. These pertinent physicochemical and surface properties of unmodified and modified N 220 carbon black have been studied in relation to N-vinylcarbazole polymerization. 相似文献