Synthesis and comparative molecular field analysis (CoMFA) of antitumor 3-arylisoquinoline derivatives

In this study a series of 3-arylisoquinoline derivatives were synthesized and cytotoxicity against human melanoma tumor cell evaluated, and a three dimensional quantitative structure-activity relationship was investigated using the comparative molecular field analysis (CoMFA). The results suggested that the electrostatic, steric and hydrophobic factors of 3-arylisoquinolines were strongly correlated with the antitumor activity. Considerable predictive ability (cross-validated r2 as high as 0.721) was obtained through CoMFA.     

Stability analysis for discrete linear systems with state saturation by a saturation-dependent Lyapunov functional

This paper concerns the stability analysis problem of discrete linear systems with state saturation using a saturation-dependent Lyapunov functional.We introduce a free matrix characterized by the sum of the absolute value of each elements for each row less than 1,which makes the state with saturation constraint reside in a convex polyhedron.A saturation-dependent Lyapunov functional is then designed to obtain a sufficient condition for such systems to be globally asymptotically stable.Based on this stability criterion,the state feedback control law synthesis problem is also studied.The obtained results are formulated in terms of bilinear matrix inequalities that can be solved by the presented iterative linear matrix inequality algorithm.Two numerical examples are used to demonstrate the effectiveness of the proposed method.     

隔离开关二次回路防误闭锁改造与应用

分析泉州电业局220kV老式变电站原隔离开关二次防误闭锁回路存在的隐患,针对改造前存在的安全问题,提出了改造措施。     

基于MACH 4002交换机的煤矿网络系统

以MACH 4002交换机为网络核心,分析了煤矿环境对网络系统的实时性、可靠性要求,比较了多种拓扑结构特性,给出了行之有效的建设方案。     

电视监控系统云台控制器设计

电视监控系统是一种典型的分布式计算机信号采集系统。为了提高监控的范围和效果,云台控制器的优劣直接影响监控的范围和效果,因此对云台控制器的设计具有重要的意义。本系统采用串型通信,通过Modbus协议把控制信号输入单片机,经过对AT89S52单片机的编程,从而对八路继电器输出进行控制。系统不仅结构简单,而且还可以方便的对镜头、防护罩的控制进行扩展,功能强大,可以广泛应用于电视监控系统中的云台控制。     

基于Android的多功能文件管理系统的设计与实现

文章所涉内容是一款基于Android的多功能文件管理系统的设计与实现。该设计以Android系统为开发平台,其目的是开发出一种方便用户使用的管理软件,使其具有文件浏览、文件权限的修改、添加文件到文件库、文件历史记录浏览、文件压缩以及文件加密等功能。     

改进BP网络在航材需求预测中的应用

针对航材备件需求预测问题,在对影响航材备件需求量的多个因素进行分析研究的基础上,运用改进BP神经网络算法进行预测的仿真实验。实验结果表明,改进BP神经网络能够对积累的历史数据进行充分的应用,并且有较高的预测准确性。     

Automatic Channel Detection Using DNN on 2D Seismic Data

Geologists interpret seismic data to understand subsurface properties and subsequently to locate underground hydrocarbon resources. Channels are among the most important geological features interpreters analyze to locate petroleum reservoirs. However, manual channel picking is both time consuming and tedious. Moreover, similar to any other process dependent on human intervention, manual channel picking is error prone and inconsistent. To address these issues, automatic channel detection is both necessary and important for efficient and accurate seismic interpretation. Modern systems make use of real-time image processing techniques for different tasks. Automatic channel detection is a combination of different mathematical methods in digital image processing that can identify streaks within the images called channels that are important to the oil companies. In this paper, we propose an innovative automatic channel detection algorithm based on machine learning techniques. The new algorithm can identify channels in seismic data/images fully automatically and tremendously increases the efficiency and accuracy of the interpretation process. The algorithm uses deep neural network to train the classifier with both the channel and non-channel patches. We provide a field data example to demonstrate the performance of the new algorithm. The training phase gave a maximum accuracy of 84.6% for the classifier and it performed even better in the testing phase, giving a maximum accuracy of 90%.     

The Bivariate Transmuted Family of Distributions: Theory and Applications

The bivariate distributions are useful in simultaneous modeling of two random variables. These distributions provide a way to model models. The bivariate families of distributions are not much widely explored and in this article a new family of bivariate distributions is proposed. The new family will extend the univariate transmuted family of distributions and will be helpful in modeling complex joint phenomenon. Statistical properties of the new family of distributions are explored which include marginal and conditional distributions, conditional moments, product and ratio moments, bivariate reliability and bivariate hazard rate functions. The maximum likelihood estimation (MLE) for parameters of the family is also carried out. The proposed bivariate family of distributions is studied for the Weibull baseline distributions giving rise to bivariate transmuted Weibull (BTW) distribution. The new bivariate transmuted Weibull distribution is explored in detail. Statistical properties of the new BTW distribution are studied which include the marginal and conditional distributions, product, ratio and conditional momenst. The hazard rate function of the BTW distribution is obtained. Parameter estimation of the BTW distribution is also done. Finally, real data application of the BTW distribution is given. It is observed that the proposed BTW distribution is a suitable fit for the data used.     

A dynamic variability management approach working with agile product line engineering practices for reusing features

The Journal of Supercomputing - Agile software development (ASD) and software product line (SPL) have shown significant benefits for software engineering processes and practices. Although both...