Open-hardware e-puck Linux extension board for experimental swarm robotics research

In this paper we describe the implementation of a Linux extension board for the e-puck educational mobile robot, designed to enhance the computation, memory and networking performance of the robot at very low cost. The extension board is based on a 32-bit ARM9 microprocessor and provides wireless network support. The ARM9 extension board runs in parallel with the dsPIC microprocessor on the e-puck motherboard with communication between the two via an SPI bus. The extension board is designed to handle computationally intensive image processing, wireless communication and high-level intelligent robot control algorithms, while the dsPIC handles low-level sensor interfacing, data processing and motor control. The extension board runs an embedded Linux operating system, along with a Debian-based port of the root file system stored in a Micro SD card. The extended e-puck robot platform requires minimal effort to integrate the well-known open-source robot control framework Player and, when placed within a TCP/IP networked infrastructure, provides a powerful and flexible platform for experimental swarm robotics research.     

A SAS(®) macro implementation of a multiple comparison post hoc test for a Kruskal-Wallis analysis

The Kruskal-Wallis (KW) nonparametric analysis of variance is often used instead of a standard one-way ANOVA when data are from a suspected non-normal population. The KW omnibus procedure tests for some differences between groups, but provides no specific post hoc pair wise comparisons. This paper provides a SAS^® macro implementation of a multiple comparison test based on significant Kruskal-Wallis results from the SAS NPAR1WAY procedure. The implementation is designed for up to 20 groups at a user-specified alpha significance level. A Monte-Carlo simulation compared this nonparametric procedure to commonly used parametric multiple comparison tests.     

Adaptive Sampling for Network Management

High-performance networks require sophisticated management systems to identify sources of bottlenecks and detect faults. At the same time, the impact of network queries on the latency and bandwidth available to the applications must be minimized. Adaptive techniques can be used to control and reduce the rate of sampling of network information, reducing the amount of processed data and lessening the overhead on the network. Two adaptive sampling methods are proposed in this paper based on linear prediction and fuzzy logic. The performance of these techniques is compared with conventional sampling methods by conducting simulative experiments using Internet and videoconference traffic patterns. The adaptive techniques are significantly more flexible in their ability to dynamically adjust with fluctuations in network behavior, and in some cases they are able to reduce the sample count by as much as a factor of two while maintaining the same accuracy as the best conventional sampling interval. The results illustrate that adaptive sampling provides the potential for better monitoring, control, and management of high-performance networks with higher accuracy, lower overhead, or both.     

The BIOPHILE Sample Process Management System - Automated Sample Access at Ultra Low Temperatures

The genomics, proteomics, clinical, and drug discovery laboratories have a growing need to maintain valuable samples at ultra-low (−80°C) temperatures in a validated, secure environment. Automated sample processing systems have until now required manual (off-line) storage of samples at −80°C, reducing system reliability and speed. Both of these important needs are addressed by the Sample Process Management System being introduced by BIOPHILE Inc. Conventional sample management processes, such as storage, retrieval, and cataloging, are increasingly strained by the growing sample populations. There are variable sample types, access requirements and storage requirements. Security and inventory procedures are implemented manually. The evolving technologies present in the laboratory cannot interface with conventional manual storage techniques. Addressing these limitations, the primary benefits of BIOPHILE's solutions are:

• Fully validated sample management process that coordinates the life-cycles of samples and their related data.

• Robotic technology to securely store and retrieve samples, improving their accessibility and stability. Thermal shock is reduced, improving sample longevity and quality. The robotic technology allows integration with larger automation systems.

• A process program to develop a Sample Management Strategy. This strategy is developed by analyzing long-term research goals, current baseline processes, and identification of current sample life cycles. A full validation documentation package can be generated, providing a high level of quality assurance.

• Improved sample visibility and quality assurance - automated sample population cataloging; controlled sample management access and security.

     

Learning first-order probabilistic models with combining rules

Many real-world domains exhibit rich relational structure and stochasticity and motivate the development of models that combine predicate logic with probabilities. These models describe probabilistic influences between attributes of objects that are related to each other through known domain relationships. To keep these models succinct, each such influence is considered independent of others, which is called the assumption of “independence of causal influences” (ICI). In this paper, we describe a language that consists of quantified conditional influence statements and captures most relational probabilistic models based on directed graphs. The influences due to different statements are combined using a set of combining rules such as Noisy-OR. We motivate and introduce multi-level combining rules, where the lower level rules combine the influences due to different ground instances of the same statement, and the upper level rules combine the influences due to different statements. We present algorithms and empirical results for parameter learning in the presence of such combining rules. Specifically, we derive and implement algorithms based on gradient descent and expectation maximization for different combining rules and evaluate them on synthetic data and on a real-world task. The results demonstrate that the algorithms are able to learn both the conditional probability distributions of the influence statements and the parameters of the combining rules.     

MobGeoSen: facilitating personal geosensor data collection and visualization using mobile phones

Mobile sensing and mapping applications are becoming more prevalent because sensing hardware is becoming more portable and more affordable. However, most of the hardware uses small numbers of fixed sensors that report and share multiple sets of environmental data which raises privacy concerns. Instead, these systems can be decentralized and managed by individuals in their public and private spaces. This paper describes a robust system called MobGeoSens which enables individuals to monitor their local environment (e.g. pollution and temperature) and their private spaces (e.g. activities and health) by using mobile phones in their day to day life. The MobGeoSen is a combination of software components that facilitates the phone’s internal sensing devices (e.g. microphone and camera) and external wireless sensors (e.g. data loggers and GPS receivers) for data collection. It also adds a new dimension of spatial localization to the data collection process and provides the user with both textual and spatial cartographic displays. While collecting the data, individuals can interactively add annotations and photos which are automatically added and integrated in the visualization file/log. This makes it easy to visualize the data, photos and annotations on a spatial and temporal visualization tool. In addition, the paper will present ways in which mobile phones can be used as noise sensors using an on-device microphone. Finally, we present our experiences with school children using the above mentioned system to measure their exposure to environmental pollution.

Atomic computing

Technological progress comes from pushing hard at the limitsof what is currently possible, not from merely following trendsothers have set. In computing a good illustration of this principleis the life and work of the 19th century computer pioneer CharlesBabbage (1791-1870), who spent most of his adult life tryingto build a digital computer. Babbage first invented such a machinein 1834. He called it the Analytical Engine.     

Top-down proteomic analysis by MALDI-TOF profiling: Concentration-independent biomarkers

Although numerous protein biomarkers have been correlated with advanced disease states, no new clinical assays have been developed. Goals often anticipate disease-specific protein changes that exceed values among healthy individuals, a property common to acute phase reactants. This review considers somewhat different approaches. It focuses on intact protein isoform ratios that present a biomarker without change in the total concentration of the protein. These will seldom be detected by peptide level analysis or by most antibody-based assays. For example, application of an inexpensive method to large sample groups resulted in observation of several polymorphisms, including the first structural polymorphism of apolipoprotein C1. Isoform distribution of this protein was altered and was eventually linked to increased obesity. Numerous other protein isoforms included C- and N-terminal proteolysis, changes of glycoisoform ratios and certain types of sulfhydryl oxidation. While many of these gave excellent statistical correlation with advanced disease, clinical utility was not apparent. More important may be that protein isoform ratios were very stable in each individual. Diagnosis by longitudinal analysis of the same individual might increase sensitivity of protein biomarkers by 20-fold or more. Protein changes that exceed the range of values found among healthy individuals may be uncommon.