Optimization of the properties obtained by quenching in martensitic stainless steels X30-40Cr13 and X40-60CrMoV14

An experimental study of the effects produced by different parameters of the heat-quenching cycle permitted the optimization of the properties typical of these martensitic stainless steels: hardness and corrosion resistance. The results obtained demonstrate that the heating temperatures currently used in industrial quenching treatment of these steels should be modified.     

Arteriovenous malformation presenting as a complex pelvic mass with ureteral obstruction. A case report

BACKGROUND: Arteriovenous malformations (AVMs) are an abnormal communication between arterial and venous structures. Pelvic AVMs have been infrequently described in the literature and represent an uncommon cause of a palpable pelvic mass. CASE: A case of pelvic AVM with ureteral obstruction occurred. The location and radiologic appearance of the AVM suggested a complex adnexal mass. During exploration and resection of the mass, significant bleeding was encountered. The diagnosis of AVM was made only retrospectively, with histologic examination of the specimen. CONCLUSION: AVMs are an uncommon and unique cause of pelvic pathology. Preoperative diagnosis will alert the surgeon as to the technically difficult resection that may be encountered and to the massive bleeding that can be associated with their removal.     

Multi-plant production scheduling in SMEs

Traditionally, companies used to view themselves as separate entities and did not devote efforts to collaborate with other echelons of the extended enterprise. This even happened at multi-site companies owning different plants that belonged to the same supply chain. However, manufacturing facilities of the same supply chain should intensively share information and coordinate planning and scheduling tasks in order to get a globally optimized solution. This paper discusses some specific characteristics of the planning and scheduling problem in the extended enterprise including an analysis of a case study, and reviews the available state-of-the-art research studies in this field. Most studies suggest that integrated approaches can have a significant impact on the system performance, in terms of lower production costs, and less inventory levels. The paper provides some conclusions and suggestions of future works.     

Tolerance of volunteers to cyclosporine A-dilauroylphosphatidylcholine liposome aerosol

Cyclosporine A (CsA) in liposomes of dilauroylphosphatidylcholine (DLPC), containing 118 micrograms of CsA/L of aerosol with a particle size of 1.6 to 1.7 micron diameter, was inhaled by 10 nonsmoking, normal volunteers each for 45 min. Aerosol was administered through an Aerotech II nebulizer (CIS-US, Inc., Bedford, MA) mouthpiece. Eight of the 10 volunteers had tracheal irritation and intermittent coughing following exposure. FEV1 and FVC values were mildly reduced, but returned to normal in 1 h. Blood chemical and hematologic values were unchanged at any time point after as opposed to before inhalation. Nine of the 10 volunteers later inhaled DLPC only, administered through the nebulizer mouthpiece. There was no change in FEV1 or FVC values, and there was no coughing or tracheal irritation. Subsequently, five of the volunteers who had previously had respiratory reactions inhaled CsA-DLPC liposome aerosol for 45-min, but through a mouth-only face mask. There was no tracheal irritation, coughing, or changes in spirometric measures. Blood concentrations of CsA at 15 min after the 45-min inhalation with a face mask averaged 83 +/- 42 ng/ml (mean +/- SD). At 24 h after treatment, CsA was undetectable in blood of the initial 10 volunteers. These studies indicate that CsA-DLPC liposome aerosol can be safely explored as a treatment for patients with moderately severe asthma.     

Yeast exo-β-glucanases can be used as efficient and readily detectable reporter genes in Saccharomyces cerevisiae

Yeast exo-1,3-β-glucanases are secretable proteins whose function is basically trophic and may also be involved in cell wall glucan hydrolytic processes. Since fluorescein di(β-D -glucopyranoside) is a fluorogenic substrate detectable and quantifiable by flow cytometry, it was used for testing the ability of the EXG1 gene product of Saccharomyces cerevisiae and its homologous gene in Candida albicans to function as reporter genes. These open reading frames were coupled to different promoters in multicopy plasmids, and exoglucanase activity quantified at flow cytometry. Exoglucanases were found to be useful tools for the study of promoter regions in S. cerevisiae. This technique has the advantage over other reporter gene systems—such as β-galactosidase fusions—that it does not require permeabilization of yeast cells and therefore it allows the recovery of viable cells—by sorting—after flow cytometry analysis.     

A 2.2 W, 80 MHz superscalar RISC microprocessor

A 28 mW/MHz at 80 MHz structured-custom RISC microprocessor design is described. This 32-b implementation of the PowerPC architecture is fabricated in a 3.3 V, 0.5 μm, 4-level metal CMOS technology, resulting in 1.6 million transistors in a 7.4 mm by 11.5 mm chip size. Dual 8-kilobyte instruction and data caches coupled to a high performance 32/64-b system bus and separate execution units (float, integer, loadstore, and system units) result in peak instruction rates of three instructions per clock cycle. Low-power design techniques are used throughout the entire design, including dynamically powered down execution units. Typical power dissipation is kept under 2.2 W at 80 MHz. Three distinct levels of software-programmable, static, low-power operation-for system power management are offered, resulting in standby power dissipation from 2 mW to 350 mW. CPU to bus clock ratios of 1×, 2×, 3×, and 4× are implemented to allow control of system power while maintaining processor performance. As a result, workstation level performance is packed into a low-power, low-cost design ideal for notebooks and desktop computers     

Process heat integration of a heavy crude hydrotreatment plant

The present paper focuses on the study of process alternatives for heat integration of a heavy crude oil hydrotreatment plant. Experimental information obtained from a pilot scale, kinetics and reactor modeling tools, and a commercial process simulator were employed to develop mass and energy balances. Four study cases, which employ a combination of quenching and heat exchangers, were identified and evaluated. The results indicated that the case with two quenches with hydrogen and three heat exchangers is the best process heat integration (PHI) option from an energetic point of view.     

Development of a predictive model for polymer/solvent diffusion coefficient calculations

A new calculation procedure for free‐volume parameters is considered in this work by using viscosity prediction methods and the Levenberg‐Marquardt calculation scheme. All parameters used in the Vrentas–Duda free‐volume theory can be estimated from pure component properties. The prediction results are compared with experimental data for some polymer/solvent systems. The diffusion coefficient calculated by Vrentas–Duda theory can be used in the modeling of membrane separation processes. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008     

Modelling and Simulation of a Direct Contact Rotary Dryer

A mathematical model able to predict solid and drying gas temperature and moisture content axial profiles along a direct contact rotary dryer was developed. The study was focused on the drying kinetics based on phenomenological models. Two different drying mechanisms in the decreasing drying rate period were tested: proponional to the unbound moisture content and moisture diffusion inside the particle. Experimental data collected in a pilot-scale direct contact rotary dryer was used to validate the model. Soya and fish meals were used as drying material.