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121.
The availability of tools to diagnose Wireless Sensor Network (WSN) failures is a key success factor for this type of networks as already demonstrated by several long-running deployments. By nature, WSNs are resource-constrained, fragile, complex to analyse, and failure-prone. Naturally, with the growing number of installations, it is becoming fundamental to efficiently diagnose failures as soon as possible, in order to deal with the underlying causes. In accordance with this, from 2005 onwards, the offer of diagnostic tools has been increasing, as the other base technologies (e.g. networking, operating system, localisation, synchronisation) become reasonably stable. The purpose of this survey is to provide an overview of existing post-deployment WSN diagnostic tools, by briefly presenting their functionality, architecture and constraints, in order to enable a basic understating of each tool. The survey also includes a multi-dimensional comparative analysis of the various tools, based on a proposed classification scheme and evaluation criteria, as well as an identification of the main open research issues. Although the number of diagnostic tools is high and considerable work has been done in this area, we conclude that there are still several challenges concerning post-deployment WSN diagnostic tools, regarding scope, flexibility, generality, mobility and security. Moreover, there is a need for mature, native diagnostic-oriented functionality in WSN platforms and operating systems.  相似文献   
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Clotrimazole is a common choice for the treatment of vulvovaginal infections, but its low solubility and some side effects pose a challenge to its application. This work evaluated the feasibility to formulate clotrimazole-loaded cationic nanocapsules using Eudragit® RS100 and medium chain triglycerides as polymer and oily core, respectively, by the method of interfacial deposition of a preformed polymer. The physicochemical characteristics of nanocapsule formulations were evaluated at 0 day and 60 days after preparation. Particle size, zeta potential, polydispersity index, pH and drug content were stable during this period. In addition, nanocapsules were able to protect clotrimazole from photodegradation under UV radiation. By the dialysis bag diffusion technique, the nanosized formulations showed prolonged release of clotrimazole by anomalous transport and first order kinetics. A microbiological study was carried out by the microdilution method and showed that nanocapsules (mean size: 144 nm; zeta potential: + 12 mV) maintained the antifungal activity of clotrimazole against Candida albicans and Candida glabrata strains susceptible and resistant to fluconazole.  相似文献   
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Polyesters were synthesized by direct polycondensation of thiophene‐2,5‐dicarboxylic acid and five different silarylene‐containing diphenols using a tosyl chloride/pyridine/N,N‐dimethylformamide system as a condensing agent. Polymers were obtained in good yields and were characterized using Fourier transform infrared and NMR (1H, 13C, 135‐DEPT and 29Si) spectroscopy and elemental analysis. All polymers were completely soluble in aprotic organic polar solvents such as dimethylformamide, dimethylsulfoxide and N‐methyl‐2‐pyrrolidone. The range of effective mass of the polymers (m/z) was 1 × 105–2 × 105, determined using electrospray ionization mass spectrometry. Asymmetry and steric hindrance prevented dense packing of the polymeric chains, showing glass transition temperatures between ? 78 and ? 51 °C and loss of thermal stability at 177–199 °C (10% weight loss). Additionally, the melting points of the polyesters were found to be in the range 62–67 °C. Because of this, the samples were semi‐solid at room temperature. The optical band gaps of the polymers were observed between 4.54 and 4.48 eV, corresponding in all cases to insulator behavior. The molecular structure of the samples was studied using X‐ray diffraction, showing a degree of order that was associated with two monoclinic lattices. Additionally, the conductivity was studied using a two‐point method with contacts on top of polymer films. Prior to the electrical measurement, the samples were polarized in an external electric field of 0.8 to 6.4 V cm?1, and the alignment of the dipoles increased the electrical conductivity. Copyright © 2012 Society of Chemical Industry  相似文献   
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Model management is essential for coping with the complexity introduced by the increasing number and varied nature of artifacts involved in model-driven engineering-based projects. Global model management (GMM) addresses this issue by enabling the representation of artifacts, particularly transformation composition and execution, within a model called a megamodel. Type information about artifacts can be used for preventing type errors during execution. Built on our previous work, in this paper we present the core elements of a type system for GMM that improves its original typing approach and enables both typechecking and type inference on artifacts within a megamodel. This type system is able to deal with non-trivial situations such as the use of higher order transformations. We also present a prototypical implementation of such a type system.  相似文献   
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One of the primary factors that impact the master production scheduling performance is demand fluctuation, which leads to frequently updated decisions, thereby causing instability. Consequently, global cost deteriorates, and productivity decreases. A reactive approach based on parametric mixed-integer programming (MIP) is proposed that aims to provide a set of plans such that a compromise between production cost and production stability is ensured. Several stability measures and their corresponding MIP model are proposed. An experimental study is performed to highlight the effectiveness of the reactive approach with regard to the proposed performance measures. It is observed that an improvement in stability does not mean a significant increase in the total production cost. Furthermore, the procedure yields a set of plans that in practice would enable flexible management of production.  相似文献   
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