Protein Corona Influences Cell–Biomaterial Interactions in Nanostructured Tissue Engineering Scaffolds

Biomaterials are extensively used to restore damaged tissues, in the forms of implants (e.g., tissue engineered scaffolds) or biomedical devices (e.g., pacemakers). Once in contact with the physiological environment, nanostructured biomaterials undergo modifications as a result of endogenous proteins binding to their surface. The formation of this macromolecular coating complex, known as “protein corona,” onto the surface of nanoparticles and its effect on cell–particle interactions are currently under intense investigation. In striking contrast, protein corona constructs within nanostructured porous tissue engineering scaffolds remain poorly characterized. As organismal systems are highly dynamic, it is conceivable that the formation of distinct protein corona on implanted scaffolds might itself modulate cell–extracellular matrix interactions. Here, it is reported that corona complexes formed onto the fibrils of engineered collagen scaffolds display specific, distinct, and reproducible compositions that are a signature of the tissue microenvironment as well as being indicative of the subject's health condition. Protein corona formed on collagen matrices modulated cellular secretome in a context‐specific manner ex vivo, demonstrating their role in regulating scaffold–cellular interactions. Together, these findings underscore the importance of custom‐designing personalized nanostructured biomaterials, according to the biological milieu and disease state. The use of protein corona as in situ biosensor of temporal and local biomarkers is proposed.     

Anisotropic thermal conductivity of polypropylene composites filled with carbon fibers and multiwall carbon nanotubes

Polypropylene‐based composites filled with carbon fibers and multiwall carbon nanotubes were produced by coagulation precipitation technique. Composite articles were produced by conventional injection molding technique. It was shown that the addition of carbon nanotubes (10% of total amount of carbon fibers) results in significantly increased anisotropic thermal conductivity of the composite due to formation of thermal conductive bridges between carbon fibers, which are oriented during molding. The addition of CNTs has a significant effect with more than a 50–70% increase of both the axial and transverse thermal conductivity of the composite. Produced composites were used for injection molding of polymeric radiators for LED lamps, showing sufficient heat dissipation efficiency allowing using them for industrial application in the field. POLYM. COMPOS., 36:1951–1957, 2015. © 2014 Society of Plastics Engineer     

Plasmonic molecules via glass annealing in hydrogen

Growth of self-assembled metal nanoislands on the surface of silver ion-exchanged glasses via their thermal processing in hydrogen followed by out-diffusion of neutral silver is studied. The combination of thermal poling of the ion-exchanged glass with structured electrode and silver out-diffusion was used for simple formation of separated groups of several metal nanoislands presenting plasmonic molecules. The kinetics of nanoisland formation and temporal evolution of their size distribution on the surface of poled and unpoled glass are modeled.

PACS

78.67.Sc (nanoaggregates; nanocomposites); 81.16.Dn (self-assembly); 68.35.bj (surface structure of glasses); 64.60.Qb (Nucleation); 81.16.Nd (micro- and nanolithography)     

Terahertz Switching Focuser Based on Thin Film Vanadium Dioxide Zone Plate

In this paper, we propose a switchable focuser device based on a Fresnel zone plate (FZP) structure for terahertz (THz) applications. Each FZP contains seven rings, etched in thin VO₂ film with the designed focal lengths of 50 and 100 mm for 3.7-THz frequency. Temperature-induced VO₂ phase transition leads to the change in dielectric susceptibility of the material, which allows one to switch on and off the focusing properties of the device. The devices were tested with radiation of 3.1 and 3.7 THz emitted by quantum cascade lasers. Experimental results were compared with numerical simulations. In this article, we compare the FZP based on VO₂ films with different properties and show that a thicker VO₂ film reveals higher focusing efficiency, while a thinner one reveals a higher modulation ratio for the peak intensity at the focal point of FZP. We demonstrate experimentally the near-diffraction-limited size of the beam in the focal point of the device. Switching between two phase states of the VO₂ films results in up to the 38-fold change of intensity in the focal point.     

A sliding mode controller for a model of flow separation in boundary layers

In this paper, we propose a sliding mode controller for a MIMO model of flow separation in boundary layers. The model consists in a bilinear system with constant delays in both the state and the input. The main motivation to consider such a class of systems is that it has shown to be suitable for input‐output modeling and control design of some turbulent flow control systems. Stability and robustness properties of the control scheme are studied by means of Volterra equations theory, which provides easily verifiable stability conditions.     

Sea state in the Baltic Sea from space-borne high-resolution synthetic aperture radar imagery

In this work, remote sensing synthetic aperture radar (SAR) data from X-band TerraSAR-X and TanDEM-X (TS-X and TD-X) satellites have been used to adopt the algorithms for estimating sea state parameters in the specific condition of the Baltic Sea with archipelago islands and where short steep sea state dominates. Since the moving targets can be defocused and shifted in SAR images, sea state consisting of short windsea waves with strong local orbital velocities and wave breaking needs additional effort for accurate estimation of the total significant wave height that consists of swell and windsea parts. The XWAVE_C algorithm, developed for the North Sea, where the long swell waves coming from the Atlantic Ocean are present during storms, was further enhanced for the short steep windsea which dominates under ordinary storm conditions in the Baltics. For the empirical XWAVE_C model function, based on the spectral analysis of subscenes as well as on local wind information, an additional term was incorporated for assessment the minimal windsea significant wave height by applying JONSWAP wave spectra. A term to compensate spectral distortions triggered by windsea waves moving in SAR flight direction has also been introduced. In total, 95 TS-X/TD-X StripMap scenes between 2012 and 2017 were acquired in Eastern Baltic Sea, processed and analysed. The wave height results from SAR images were compared with collocated in situ data from 11 available buoys. The analysed data include both high and low windsea conditions. The comparison of SAR-derived wave heights with measured wave heights shows high agreement with a correlation coefficient r of 0.88. The wind speed, estimated from SAR images, was compared to measurements from 14 collocated in situ stations, yielding a high agreement with an r value of 0.90. This article is focused on the algorithm developments; however, it is also the first study of sea state retrieval in the Baltic Sea using high-resolution satellite-based techniques. The results show the local variability in the wave fields connected to atmospheric features. The observed local wave height can increase by 1–2 m in kilometre-size cells that are accompanied by wind gusts. The developed algorithms are installed in the German Aerospace Center’s (DLR) ground station Neustrelitz and can also be used in near-real-time.     

Towards engineering in memristors for emerging memory and neuromorphic computing:A review

Resistive random-access memory(RRAM),also known as memristors,having a very simple device structure with two terminals,fulfill almost all of the fundamental requirements of volatile memory,nonvolatile memory,and neuromorphic characteristics.Its memory and neuromorphic behaviors are currently being explored in relation to a range of materials,such as biological materials,perovskites,2D materials,and transition metal oxides.In this review,we discuss the different electrical behaviors exhibited by RRAM devices based on these materials by briefly explaining their corresponding switching mechanisms.We then discuss emergent memory technologies using memristors,together with its potential neuromorphic applications,by elucidating the different material engineering techniques used during device fabrication to improve the memory and neuromorphic performance of devices,in areas such as ION/IOFF ratio,endurance,spike time-dependent plasticity(STDP),and paired-pulse facilitation(PPF),among others.The emulation of essential biological synaptic functions realized in various switching materials,including inorganic metal oxides and new organic materials,as well as diverse device structures such as single-layer and multilayer hetero-structured devices,and crossbar arrays,is analyzed in detail.Finally,we discuss current challenges and future prospects for the development of inorganic and new materials-based memristors.     

Structural and physicochemical studies of hydration of crosslinked TBA polyacrylates with different substitution degrees of H+ ions with TBA+ ions

X‐ray powder diffraction studies and physicochemical studies have been carried out of the hydrate phases formed in binary water systems with crosslinked tetrabutylammonium (TBA) polyacrylates (n = 1%) in mixed [x(C₄H₉)₄N + (100?x)H] form with low degrees of substitution of proton ions of the carboxylic groups in poly(acrylic acid) for TBA cations x = 40%, 30%, and 20%. As was shown by structural studies, the clathrate hydrate is formed in the water system with the polyacrylate in the mixed form with x = 40%. The structure is analogous to that of earlier studied hydrates formed by crosslinked polyacrylates in mixed [x(C₄H₉)₄N + (100?x)H] form with higher values of x = ～100%, 80%, and 60% and can be related to the tetragonal structure I, characteristic of the ionic clathrate hydrates of TBA salts with monomeric anions. Decomposition temperature and fusion enthalpy of the studied hydrate were determined using differential thermal analysis and calorimetric methods. It was revealed that the further decrease of x led to the destruction of clathrate hydrate framework. According to the results of X‐ray powder diffraction research, the phase of ice is crystallized instead of the hydrate phase in water systems with the polyacrylates with x = 30% and 20%. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135, 46209.