A structural VAR analysis of electricity consumption and real GDP: Evidence from the G7 countries

In this paper, we depart from the literature on electricity consumption–real GDP in that for the first time we examine the reaction of real GDP to shocks in electricity consumption. To achieve this goal, we use the structural vector autoregressive (SVAR) model and examine the impact of electricity consumption shocks on real GDP for the G7 countries. We find that except for the USA, electricity consumption has a statistically significant positive impact on real GDP over short horizons. This finding implies that except for the USA, electricity conservation policies will hurt real GDP in the G7 countries.     

Microprocessor in controlled transdermal drug delivery of anti-cancer drugs

Microprocessor controlled transdermal delivery of anticancer drugs 5-Fluorouracil (5-FU) and 6-Mercaptopurine (6-MP) was developed and in vitro evaluation was done. Drugs were loaded based on the pharmacokinetics parameters. In vitro diffusion studies were carried at different current density (0.0, 0.1, 0.22, 0.50 mA/cm²). The patches were evaluated for the drug content, thickness, weight, folding endurance, flatness, thumb tack test and adhesive properties all were well with in the specification of transdermal patches with elegant and transparent in appearance. In vitro permeation studies through human cadaver skin showed, passive delivery (0.0 mA/cm²) of 6-MP was low. As the current density was progressively increased, the flux also increased. the flux also increased with 0.1 mA/cm² for 15–20 min, but it was less than desired flux, 0.2 mA/cm² for 30 min showed better flux than 0.1 mA/cm² current, but lag time was more than 4 h, 0.5 mA/cm² current for more than 1 h, flux was >159 µg/cm² h which was desired flux for 6-MP. 5-FU flux reached the minimum effective concentration (MEC) of 54 μg/cm² h with 0.5 mA/cm² current for 30–45 min, drug concentration were within the therapeutic window in post-current phase. We concluded from Ohm’s Law that as the resistance decreases, current increases. Skin resistance decrease with increase in time and current, increase in the drug permeation. Interestingly, for all investigated current densities, as soon as the current was switched off, 5-FU and 6-MP flux decreased fairly, but the controlled drug delivery can be achieved by switching the current for required period of time.     

Plane strain deformation in an orthotropic micropolar thermoelastic solid with a heat source

The problem of plane strain deformation in an orthotropic micropolar generalized thermoelastic half-space subjected to an arbitrary point heat source is solved. Closed-form solutions for spatial distributions of displacements, stresses, and temperature are derived by using the Fourier transform. A numerical inversion technique has been applied to obtain the solution in the physical domain. Numerical results are obtained and presented graphically along with a comparison of the ones for concentrated and distributed, as well as mechanical and thermal, sources.     

Bi-objective optimization of the reliability-redundancy allocation problem for series-parallel system

The main objective of this paper is to solve the bi-objective reliability redundancy allocation problem for series-parallel system where reliability of the system and the corresponding designing cost are considered as two different objectives. In their formulation, reliability of each component is considered as a triangular fuzzy number. In order to solve the problem, developed fuzzy model is converted to a crisp model by using expected values of fuzzy numbers and taking into account the preference of decision maker regarding cost and reliability goals. Finally the obtained crisp optimization problem has been solved with particle swarm optimization (PSO) and compared their results with genetic algorithm (GA). Examples are shown to illustrate the method. Finally statistical simulation has been performed for supremacy the approach.     

Synthesis of Triphenylethylene-Naphthalimide Conjugates as topoisomerase-IIα inhibitor and HSA binder

A series of triphenylethylene-naphthalimide (TPE-naph) conjugates was synthesized by a molecular hybridization technique, and their anticancer activity was evaluated in vitro on 60 human cancer cell lines through their cytotoxicity. The ratios of E and Z isomers were determined on the basis of HPLC methodology and NMR spectroscopy. The structure-activity relationship for anticancer activity was deduced on the basis of the nature and bulkiness of the amine attached to the C-4 position of the naphthalene ring. Experimental and molecular modeling studies of the most active TPE-naph conjugate bearing a morpholinyl group showed that it was able to inhibit topoisomerase-II (TOPO-II) as a possible intracellular target. Moreover, the transportation behavior of TPE-naph conjugate towards human serum albumin (HSA) indicated efficient binding affinity. The steady-state and time-dependent fluorescent results suggested that this conjugate quenched HSA significantly through static as well as dynamic quenching. Thus, this report discloses the scope of triphenylethylene-naphthalimide (TPE-naph) conjugates as efficient anticancer agents.     

Large-scale single-step synthesis of wrinkled N–S doped 3D graphene like nanosheets from Tender palm shoots for high energy density supercapacitors

Herein, we present a simple, large-scale and low-cost process to develop hierarchically porous N–S co-doped 3D wrinkled graphene like nanosheets (3D H-GNS) from carbonization of biomass Tender palm shoots and NaHCO₃. Non-corrosive and non-toxic Na₂CO₃ acts as a reaction mean to control the activation process, developing 3D H-GNS with a high specific surface area of 2095 m² g^?1. A 3D H-GNS-900 electrode exhibits a high specific capacitance of 529 F g^?1 (1.5 A g^?1) and 330 F g^?1 (1 A g^?1) in 1 M H₂SO₄ for 3-electrode and 2-electrode systems respectively. Further, a longer cycle life with 93% capacitance retention over 10,000 cycles at 5 A g^?1 is realized. Also, we are successful in fabricating biocompatible solid-state flexible supercapacitor device with 3D H-GNS-900 electrodes in organic electrolyte with 3 V voltage range, demonstrating to run a toy fan and lightning a LED for 15 min after charging for 60 s.     

A HGGSA Approach to Beam Forming for DOA Estimation in Smart Antenna Arrays

Beam forming is one of the most important processes in smart antenna systems for DOA estimation. The most important function in beam forming is changing beam pattern of antenna for a particular angle. If the antenna does not change the position for the specified angle, the signal losses will be high. For avoiding this, a hybrid method, called HGGSA (hybrid genetic and gravity search algorithm) is proposed that is developed by combining genetic algorithm and GSA to beam forming for DOA estimation in smart antenna arrays. In the proposed method, if an angle is given as input, it will give the maximum signal gain in the beam pattern of the antenna with corresponding position and phase angle after searching through the space based on the HGGSA algorithm.

     

Recommender system: prediction/diagnosis of breast cancer using hybrid machine learning algorithm

Multimedia Tools and Applications - Breast cancer is the second popular cause of the women’s death. There are some existing techniques for identifying the breast cancer and one of them is...     

Salient object based visual sentiment analysis by combining deep features and handcrafted features

Multimedia Tools and Applications - With the rapid growth of social networks, the visual sentiment analysis has quickly emerged for opinion mining. Recent study reveals that the sentiments conveyed...     

An extractive text summarization approach using tagged-LDA based topic modeling

Multimedia Tools and Applications - Automatic text summarization is an exertion of contriving the abridged form of a text document covering salient knowledge. Numerous statistical, linguistic,...