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91.
Bragg gratings used as input-output couplers in polymeric waveguides have been demonstrated at infrared wavelengths. These Bragg grating couplers were holographically formed volume phase gratings with a near-45 degrees fringe slant angle embedded directly into a waveguide layer. A photopolymer was used for both producing a planar waveguide and constructing the embedded Bragg grating coupler. A coupling efficiency of 23% for input and 5% for output has been achieved at 850 nm. The output-coupling beam profiles are also discussed. 相似文献
92.
HL Hinds CT Ashley JS Sutcliffe DL Nelson ST Warren DE Housman M Schalling 《Canadian Metallurgical Quarterly》1993,3(1):36-43
Prostaglandin E2 levels in isolated rat islets were increased from 64 +/- 11 pg/30 islets when incubated in medium containing 2 mM glucose to 115 +/- 9 pg/30 islets in medium containing 20 mM glucose. In contrast, glyceraldehyde (10 mM) reduced prostaglandin E2 levels to 29 +/- 6 pg/30 islets. Inhibition of glucose metabolism by mannoheptulose (10 mM) abolished the stimulatory effect of glucose on prostaglandin E2 levels and inhibited glucose-induced insulin release. The cyclooxygenase inhibitor, flurbiprofen (20 microM), did not affect insulin release caused by glucose or glyceraldehyde. In the presence of 1 mg/ml bovine serum albumin, insulin secretion induced by 20 mM glucose (6.9 +/- 1.1% of islet insulin content) was reduced by the lipoxygenase inhibitor BW755 C (20 microM) to 3.1 +/- 0.6%, and by the phospholipase A2 inhibitor, p-bromophenacyl bromide (10 microM), to 2.1 +/- 0.8%. In the absence of bovine serum albumin the inhibitory action of BW755 C and p-bromophenacyl bromide on glucose-induced insulin release was significantly more pronounced. These drugs whether in the presence or absence of bovine serum albumin, did not affect glyceraldehyde-stimulated insulin secretion. Glyceraldehyde (10 mM), potentiated glucose-induced insulin release in the presence of 2-8 mM glucose, but not for 10-20 mM glucose. Although the phospholipase A2 activator, melittin, initiated insulin release in the presence of 2 mM glucose and enhanced 10 mM glyceraldehyde-stimulated insulin secretion it had no effect on 20 mM glucose-induced insulin release. These two stimulatory effects of melittin on insulin release were totally abolished by p-bromophenacyl bromide.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
93.
Roisman Glenn I.; Holland Ashley; Fortuna Keren; Fraley R. Chris; Clausell Eric; Clarke Alexis 《Canadian Metallurgical Quarterly》2007,92(4):678
Although 10 studies have been published on the empirical overlap of the Adult Attachment Interview (AAI) and measures of self-reported attachment style, results in this literature have been inconsistently interpreted in narrative reviews. This report was designed as a rapprochement of the AAI and attachment style literatures and includes 3 studies. Study 1 (combined N = 961) is a meta-analytic review showing that by J. Cohen's (1992) criteria (mean r = .09), the association between AAI security and attachment style dimensions is trivial to small. Study 2 (N = 160) confirms meta-analytic results with state-of-the-art assessments of attachment security and also examines attachment dimensions in relation to the Big 5 personality traits. Finally, Study 3 is an investigation of 50 engaged couples that shows that developmental and social psychological measures of attachment security predict somewhat distinct--though theoretically anticipated--aspects of functioning in adult relationships. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
94.
Don Ashley 《电子产品世界》2007,(10):68-68,70
引言 作为白炽灯的替换品,LED灯近年来才开始推出市场,但却面临着诸多难题.由于将LED功率驱动电路装入标准灯壳具有难度,因此早期的一些LED灯并没有内部滤波器,也就谈不上符合EMC标准. 相似文献
95.
PU Reber MP Lewis AG Patel A Andren-Sandberg SW Ashley HA Reber 《Canadian Metallurgical Quarterly》1998,43(12):2610-2615
Ethanol is a common cause of both acute and chronic pancreatitis. Studies in other organs suggest that polymorphonuclear neutrophils activated by ethanol may cause tissue injury in a variety of conditions. The aim of this study was to investigate the effects of ethanol on neutrophil extravasation in the feline pancreas. Pancreata were isolated and perfused at different flow rates with varying concentrations of ethanol in either a physiological or neutrophil depleted perfusate. Neutrophil extravasation was assessed by measuring pancreatic tissue myeloperoxidase (MPO) activity. Ethanol at 2.5% (54.25 mmol/liter) was the lowest concentration that still caused significant neutrophil extravasation (3.1+/-0.8 vs 1.9+/-0.2 units, P<0.05) and was accompanied by an increase in vascular resistance of 15%. Reduction of pancreatic perfusion by 15% did not significantly increase neutrophil extravasation. (1.1+/-0.3 vs 1.6+/-0.2 units, NS) Perfusion of the pancreas with neutrophil-depleted blood containing either ethanol or saline, followed by perfusion with an ethanol-free perfusate, showed an increase in neutrophil extravasation in the ethanol group compared to the control group (3.2+/-0.9 vs 1.9+/-0.2 units, P<0.05). In conclusion, ethanol causes neutrophil extravasation in the feline pancreas independent of blood flow changes and occurs despite the absence of direct neutrophil exposure to ethanol. 相似文献
96.
IR Williams EA Rawson L Manning T Karaoli BE Rich TS Kupper 《Canadian Metallurgical Quarterly》1997,159(6):3044-3056
IL-7 is a keratinocyte-derived lymphocyte growth factor critical for the development of gammadelta T cells including murine dendritic epidermal T cells (DETC). We derived transgenic mice that overexpress IL-7 in basal keratinocytes under the control of the human K14 promoter. These K14/IL-7 mice develop dermal and epidermal T cell infiltrates associated with alopecia. This lymphoproliferative skin disease is substantially more severe in mice homozygous for the K14/IL-7 transgene. Conventional DETC expressing a Vgamma5 Vdelta1 TCR are rare or absent among the cutaneous T cells in these mice. The T cells in the skin infiltrates of young K14/IL-7 mice are predominantly gammadelta T cells that express intermediate levels of TCR, are negative for E-cadherin, often lack expression of CD2, and include cells that coexpress NK1.1. T cells expressing intermediate levels of a TCR-alphabeta are also present in transgenic skin, and progressively increase in number as the mice age. Phenotypically similar intermediate gammadelta and alphabeta T cell subsets also constitute the major lymphocyte populations recovered from organ culture of normal mouse skin in the presence of IL-7, suggesting that the T cells that accumulate in the epidermis of K14/IL-7 mice are derived from precursors normally resident in skin. We conclude that intermediate TCR cells, some of which coexpress NK1.1, can be selectively expanded in skin under the influence of IL-7 produced locally. Our results also suggest that features of the epidermal microenvironment besides keratinocyte-derived IL-7 account for the normal predominance of Vgamma5 Vdelta1 DETC in mouse epidermis. 相似文献
97.
J. Alison Bryant Ashley Sanders-Jackson Amber M. K. Smallwood 《Journal of Computer-Mediated Communication》2006,11(2):577-592
Building on previous research in computer-mediated communication, social and communication networks, and adolescent development, this article raises three issues regarding adolescent use of socially interactive technologies (SITs) and their relationship to offline social networks: 1) whether adolescents are creating more, but weaker ties using SITs, 2) to what extent adolescent SIT-facilitated networks overlap with friendship networks, and 3) whether SIT relationships are important for adolescents who have fewer offline peer ties. In order to investigate these questions, network data collection and analysis were integrated with more traditional questionnaire methodology and statistical analysis. The results show that the adolescents in the study were not creating more ties using SITs, nor were they necessarily creating weaker SIT-based ties; that there was little overlap between SIT-facilitated and offline social networks; and that socially isolated adolescents were less likely than other adolescents to use SITs. 相似文献
98.
Watson M.D. Ashley P.R. Abushagur M.A.G. 《Quantum Electronics, IEEE Journal of》2004,40(11):1555-1561
A charge density and current density model of a waveguide system has been developed to explore the effects of electric field electrode poling. An optical waveguide is modeled during poling by considering the dielectric charge distribution, polarization charge distribution, and conduction charge generated by the poling field. The charge distributions are the source of poling current densities. The model shows that boundary charge current density and polarization current density are the major source of currents measured during poling and thermally stimulated discharge measurements. Charge distributions provide insight into the poling mechanisms and are directly related to E/sub A/ and /spl alpha//sub r/. Initial comparisons with experimental data show excellent correlation to the model results. 相似文献
99.
Abbie E Smith Ashley A Walter Jennifer L Graef Kristina L Kendall Jordan R Moon Christopher M Lockwood David H Fukuda Travis W Beck Joel T Cramer Jeffrey R Stout 《Journal of the International Society of Sports Nutrition》2009,6(1):5
Background
Intermittent bouts of high-intensity exercise result in diminished stores of energy substrates, followed by an accumulation of metabolites, promoting chronic physiological adaptations. In addition, β-alanine has been accepted has an effective physiological hydrogen ion (H+) buffer. Concurrent high-intensity interval training (HIIT) and β-alanine supplementation may result in greater adaptations than HIIT alone. The purpose of the current study was to evaluate the effects of combining β-alanine supplementation with high-intensity interval training (HIIT) on endurance performance and aerobic metabolism in recreationally active college-aged men. 相似文献100.
Ashley T. Dean A.B. Elliott C.T. McConville C.F. Whitehouse C.R. 《Electronics letters》1988,24(20):1270-1272
Molecular-beam epitaxy has been used for the first time to fabricate np junctions in InSb grown onto p -type InSb (100) substrates. Diodes formed by the epitaxial growth of a silicon-doped layer on undoped homoepitaxial material exhibited a bulk generation-recombination-limited R 0A value of 105 Ω cm2 and D λpk * of 3×1012 cm Hz1/2 W-1 at liquid nitrogen temperature 相似文献