Quantification of Entrainment Using an Optical Inline Probe

In distillation and absorption processes, entrainment above trays or packings reduces stage and column efficiency. A modified version of the optical multimode online probe enables a seminal insight and, thus, quantification of entrained droplets on various axial and radial positions. A purging mechanism inhibits precipitation of droplets on the front lenses, while telecentric optics and illumination provide distance‐independent and precise imaging of entrained droplets between two valve trays. Experiments were performed in a DN 450 cold flow (air‐water) test rig. The results were compared with noninvasive phase Doppler anemometry data.     

iPSC-Cardiomyocyte Models of Brugada Syndrome—Achievements,Challenges and Future Perspectives

Brugada syndrome (BrS) is an inherited cardiac arrhythmia that predisposes to ventricular fibrillation and sudden cardiac death. It originates from oligogenic alterations that affect cardiac ion channels or their accessory proteins. The main hurdle for the study of the functional effects of those variants is the need for a specific model that mimics the complex environment of human cardiomyocytes. Traditionally, animal models or transient heterologous expression systems are applied for electrophysiological investigations, each of these models having their limitations. The ability to create induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs), providing a source of human patient-specific cells, offers new opportunities in the field of cardiac disease modelling. Contemporary iPSC-CMs constitute the best possible in vitro model to study complex cardiac arrhythmia syndromes such as BrS. To date, thirteen reports on iPSC-CM models for BrS have been published and with this review we provide an overview of the current findings, with a focus on the electrophysiological parameters. We also discuss the methods that are used for cell derivation and data acquisition. In the end, we critically evaluate the knowledge gained by the use of these iPSC-CM models and discuss challenges and future perspectives for iPSC-CMs in the study of BrS and other arrhythmias.     

Quantum ballistic transport in the junctionless nanowire pinch-off field effect transistor

In this work we investigate quantum ballistic transport in ultrasmall junctionless and inversion mode semiconducting nanowire transistors within the framework of the self-consistent Schrödinger-Poisson problem. The quantum transmitting boundary method is used to generate open boundary conditions between the active region and the electron reservoirs. We adopt a subband decomposition approach to make the problem numerically tractable and make a comparison of four different numerical approaches to solve the self-consistent Schrödinger-Poisson problem. Finally we discuss the IV-characteristics for small (r≤5 nm) GaAs nanowire transistors. The novel junctionless pinch-off FET or junctionless nanowire transistor is extensively compared with the gate-all-around (GAA) nanowire MOSFET.     

Adult Parasitoids of Honeydew-Producing Insects Prefer Honeydew Sugars to Cover their Energetic Needs

To meet their carbohydrate requirements, adult parasitoids exploit a broad range of sugar resources, including floral and extrafloral nectar and honeydew. Although honeydew might be the predominant sugar source, especially in agricultural systems, it often is nutritionally inferior to sugar sources like nectar. Given its broad availability, it may be expected that sugar-feeding insects have evolved specialized adaptations to deal with this typically inferior sugar source. This would apply especially to organisms that have a close association with honeydew producers. Here, we hypothesized that parasitoids of honeydew-producing insects should show a pronounced response to sugars, such as fructose, sucrose, melezitose, and trehalose, and to a lesser extent glucose. To test this hypothesis, we investigated sugar consumption, feeding behavior and survival of the aphid parasitoid Aphidius ervi on several sugars (equiweight solutions). Our results show that A. ervi adults consumed typical honeydew sugars (sucrose, fructose, trehalose, and melezitose) the most, while consuming considerably less glucose or melibiose. Rhamnose, which does not occur in aphid honeydew, was not, or was only marginally, consumed. When different sugars were provided at the same time, A. ervi adults preferred sucrose or fructose over glucose or melezitose. Furthermore, pre-exposure to sucrose or fructose significantly reduced subsequent intake of glucose, suggesting an acquired distaste for glucose after being previously exposed to highly preferred sugars such as sucrose and fructose. Altogether, this study shows that A. ervi adults prefer sugars (fructose, melezitose, trehalose, and sucrose) that are overrepresented in aphid honeydew and show a lower preference to one (glucose) that is underrepresented in honeydew.     

Us and them: a social capital perspective on the relationship between the business and IT departments

In this paper, a social capital perspective is applied to the relationship between the IT department and the Business organization. IT and Business are conceptualized as different occupational communities, with different understandings of their work. Our focus is on the level of social capital and the process of knowledge sharing between these occupational communities. We analyze the role that these factors play in reaching a mutual understanding within the process of IS development, and the influence this has on the perceived performance of the IT organization. Our study, combining qualitative and quantitative methods, points out that a lack of social capital (structural, relational as well as cognitive) can serve as an explanation for the often problematic relationship between these communities. Our analyses also show that social capital is especially relevant for the Business organization's perception of IT performance, whereas the IT department's perception is that performance is primarily dependent on the exchange of information.     

Clogging in submerged entry nozzles

Casting high quality steel grades requires the use of a submerged entry nozzle (SEN) to prevent oxygen and nitrogen pick‐up and to achieve favourable steel flow conditions in the mould. Clogging of the SEN leads to instability of the casting operation as well as to a decrease in slab quality. To understand the interactions between liquid steel and the SEN, 156 nozzles from the Sidmar steel plant were investigated with respect to the amount of clogging. A linear relation between the clogging volume and the clogging weight was observed. This indicates that the clogging material's density remains constant during the clogging process for the different steel grades. A distinct relationship was also found between the amount of clogging and the cast steel weight. No relation between the amount of clogging and the superheating of the steel nor the steel flow rate was noticed, however. It was also concluded that for AI killed steels the high Mn (> 3000 ppm) and high C (> 500 ppm) grades cause less clogging than AI killed steel grades with low Mn content (< 3000 ppm) and that Al/Si killed steel grades cause less clogging when compared to AI killed steel grades. When comparing these different steel grades with respect to their total oxygen concentration in the ladle, it appears that steel grades, which have a low total oxygen concentration, cause less clogging in the SEN. Based on these observations three combinations SEN/steel grade were selected for further analysis with electron microscopy.     

Extension of <Emphasis Type="Italic">O</Emphasis>(<Emphasis Type="Italic">n</Emphasis> log <Emphasis Type="Italic">n</Emphasis>) Filtering Algorithms for the Unary Resource Constraint to Optional Activities

Scheduling is one of the most successful application areas of constraint programming mainly thanks to special global constraints designed to model resource restrictions. Among these global constraints, edge-finding and not-first/not-last are the most popular filtering algorithms for unary resources. In this paper we introduce new O(n log n) versions of these two filtering algorithms and one more O(n log n) filtering algorithm called detectable precedences. These algorithms use a special data structures Θ-tree and Θ-Λ-tree. These data structures are especially designed for “what-if” reasoning about a set of activities so we also propose to use them for handling so called optional activities, i.e. activities which may or may not appear on the resource. In particular, we propose new O(n log n) variants of filtering algorithms which are able to handle optional activities: overload checking, detectable precedences and not-first/not-last.     

Board-Level Information Technology Governance Effects on Organizational Performance: The Roles of Strategic Alignment and Authoritarian Governance Style

ABSTRACT

We report on two empirical studies that explore key factors that help translate information technology governance by the board of directors into organizational performance. The first study shows that strategic alignment partially mediates the effect of board-level information technology governance on performance. The second study demonstrates that authoritarian governance style negatively moderates the effect of board-level information technology governance on performance. Together, these studies open up the black box between board-level information technology governance and organizational performance.     

Regular Random k-SAT: Properties of Balanced Formulas

We consider a model for generating random k-SAT formulas, in which each literal occurs approximately the same number of times in the formula clauses (regular random and k-SAT). Our experimental results show that such regular random k-SAT instances are much harder than the usual uniform random k-SAT problems. This is in agreement with other results that show that more balanced instances of random combinatorial problems are often much more difficult to solve than uniformly random instances, even at phase transition boundaries. There are almost no formal results known for such problem distributions. The balancing constraints add a dependency between variables that complicates a standard analysis. Regular random 3-SAT exhibits a phase transition as a function of the ratio α of clauses to variables. The transition takes place at approximately α = 3.5. We show that for α > 3.78 with high probability (w.h.p.) random regular 3-SAT formulas are unsatisfiable. Specifically, the events hold with high probability if Pr when n → ∞. We also show that the analysis of a greedy algorithm proposed by Kaporis et al. for the uniform 3-SAT model can be adapted for regular random 3-SAT. In particular, we show that for formulas with ratio α < 2.46, a greedy algorithm finds a satisfying assignment with positive probability.