The impact of biophilic design in Maggie’s Centres: A meta-synthesis analysis

This paper presents a meta-synthesis conducted to identify, compare and synthesize published qualitative data related to the Maggie's Centres, as a paradigmatic architectural example in the provision of non-institutional cancer support. These centres are internationally renowned for their unique architecture, where the careful design of indoors and outdoors spaces plays a critical role in their agenda for supporting care. Previous research has thoroughly analysed this approach to therapeutic environments, not only confirming the importance of designed space as originally conceived in Maggie's philosophy but also identifying precise supporting effects associated with specific elements within their design. This paper aims to provide a new reading of Maggie's contribution to cancer support by offering an examination of all these data through the lens of biophilia, which clarifies the impact of design decisions connected to nature on cancer patients' lives. The analytic process included a systematic search strategy, extraction and classification of salient concepts using an open-coding approach, and lastly an interpretive evaluation. The systematically selected data helped to identify and rank the biophilic design parameters that appear the most critical for promoting and supporting human health and wellbeing in non-clinical therapeutic environments, from the user's perspective. It also provided a compilation of distinctive design interventions related to biophilic parameters, which provides benchmark information for future research and design guidance in these environments.     

Fabrication of Patchy Silica Microspheres with Tailor-Made Patch Functionality using Photo-Iniferter Reversible-Addition-Fragmentation Chain-Transfer (PI-RAFT) Polymerization (Small 43/2023)

Their inherent directional information renders patchy particles interesting building blocks for advanced applications in materials science. In this study, a feasible method to fabricate patchy silicon dioxide microspheres is demonstrated, which they are able to equip with tailor-made polymeric materials as patches. Their fabrication method relies on a solid-state supported microcontact printing (µCP) routine optimized for the transfer of functional groups to capillary-active substrates, which is used to introduce amino functionalities as patches to a monolayer of particles. Acting as anchor groups for polymerization, photo-iniferter reversible addition-fragmentation chain-transfer (RAFT) is used to graft polymer from the patch areas. Accordingly, particles with poly(N-acryloyl morpholine), poly(N-isopropyl acrylamide), and poly(n-butyl acrylate) are prepared as representative acrylic acid-derived functional patch materials. To facilitate their handling in water, a passivation strategy of the particles for aqueous systems is introduced. The protocol introduced here, therefore, promises a vast degree of freedom in engineering the surface properties of highly functional patchy particles. This feature is unmatched by other techniques to fabricate anisotropic colloids. The method, thus, can be considered a platform technology, culminating in the fabrication of particles that possess locally precisely formed patches on particles at a low µm scale with a high material functionality.