Silicon single electron transistors with SOI and MOSFET structures: the role of access resistances

Coulomb blockade has been widely reported in silicon and metallic structures without intentional tunnel barriers. In particular, a simple constriction in silicon-on-insulator (SOI) allows to build a three-terminal silicon single-electron transistor (SET) operating at moderate temperature. The key parameters are the access resistances confining the electrons and the size of the gate-channel overlap, which sets the Coulomb energy. Thin films of doped silicon with sheet resistance of a few tens of h/e/sup 2/ are well suited for fabricating optimized access resistances. Low doped extensions with typical resistivity 1000 /spl Omega//spl mu/m (at 300 K) are also good candidates. We illustrate this MOS-SET principle in SOI constriction and standard MOSFET of similar size. Although relying on different concepts, the ultimate MOSFET and MOS-SET are shown to be technologically close, differing mostly by the ratio between the channel resistance over the access resistance. Because this ratio is decreasing as the gate length shrinks, single electron effects should become more and more important at high temperature in the subthreshold regime of standard field effect transistor devices.     

Effect of nadroparin, a low-molecular-weight heparin, on clinical and angiographic restenosis after coronary balloon angioplasty: the FACT study. Fraxiparine Angioplastie Coronaire Transluminale

BACKGROUND: Experimental studies suggest that the antiproliferative effect of heparin after arterial injury is maximized by pretreatment. No previous studies of restenosis have used a pretreatment strategy. We designed this study to determine whether treatment with nadroparin, a low-molecular-weight heparin, started 3 days before the procedure and continued for 3 months, affected angiographic restenosis or clinical outcome after coronary angioplasty. METHODS AND RESULTS: In a prospective multicenter, double-blind, randomized trial, elective coronary angioplasty was performed on 354 patients who were treated with daily subcutaneous nadroparin (0.6 mL of 10,250 anti-Xa IU/mL) or placebo injections started 3 days before angioplasty and continued for 3 months. Angiography was performed just before and immediately after angioplasty and at follow-up. The primary study end point was angiographic restenosis, assessed by quantitative coronary angiography 3 months after balloon angioplasty. Clinical follow-up was continued up to 6 months. Clinical and procedural variables and the occurrence of periprocedural complications did not differ between groups. At angiographic follow-up, the mean minimal lumen diameter and the mean residual stenosis in the nadroparin group (1.37+/-0.66 mm, 51.9+/-21.0%) did not differ from the corresponding values in the control group (1.48+/-0.59 mm, 48.8+/-18.9%). Combined major cardiac-related clinical events (death, myocardial infarction, target lesion revascularization) did not differ between groups (30.3% versus 29.6%). CONCLUSIONS: Pretreatment with the low-molecular-weight heparin nadroparin continued for 3 months after balloon angioplasty had no beneficial effect on angiographic restenosis or on adverse clinical outcomes.     

用有源滤波电路和示波器检验D类放大器的输出

人们对D类放大器的日益接受帮助它们从线性AB类放大器那儿赢得了市场份额.这种接受并不令人吃惊,D类放大器的优点很多,但这类放大器也需要新的评估方法.     

The S-kernel: A measure of symmetry of objects

In this paper we introduce a new symmetry feature named “symmetry kernel” (SK) to support a measure of symmetry. Given any symmetry transform S, SK of a pattern P is the maximal included symmetric sub-set of P for all directions and shifts. We provide a first algorithm to exhibit this kernel where the centre of symmetry is assumed to be the centre of mass. Then we prove that, in any direction, the optimal axis corresponds to the maximal correlation of a pattern with its symmetric version. That leads to a second algorithm. The associated symmetry measure is a modified difference between the respective surfaces of a pattern and its kernel. A series of experiments supports the actual algorithm validation.     

SBLOCA long term cooling procedure for the integral type PWR

An advanced integral-type pressurized water reactor (IPWR) with a maximum thermal power of 65 MW has been developed at the Korea Atomic Energy Research Institute (KAERI). This 65 MW IPWR enhances the safety and reliability by adopting inherent safety design characteristics and an advanced passive design feature.