Experimental investigation of the effect of compression ratio and injection pressure in a direct injection diesel engine running on Jatropha methyl ester

Being a fuel of different origin, the standard design parameters of a diesel engine may not be suitable for Jatropha methyl ester (JME). This study targets at finding the effects of the engine design parameters viz. compression ratio (CR) and fuel injection pressure (IP) jointly on the performance with regard to fuel consumption (BSFC), brake thermal efficiency (BTHE) and emissions of CO, CO₂, HC, NO_x and Smoke opacity with JME as fuel. Comparison of performance and emission was done for different values of compression ratio along with injection pressure to find best possible combination for operating engine with JME. It is found that the combined increase of compression ratio and injection pressure increases the BTHE and reduces BSFC while having lower emissions. For small sized direct injection constant speed engines used for agricultural applications (3.5 kW), the optimum combination was found as CR of 18 with IP of 250 bar.     

Reliability‐based robust design optimization: A multi‐objective framework using hybrid quality loss function

In this globally competitive business environment, design engineers are constantly striving to establish new and effective tools and techniques to ensure a robust and reliable product design. Robust design (RD) and reliability‐based design approaches have shown the potential to deal with variability in the life cycle of a product. This paper explores the possibilities of combining both approaches into a single model and proposes a hybrid quality loss function‐based multi‐objective optimization model. The model is unique because it uses a hybrid form of quality loss‐based objective function that is defined in terms of desirable as well as undesirable deviations to obtain efficient design points with minimum quality loss. The proposed approach attempts to optimize the product design by addressing quality loss, variability, and life‐cycle issues simultaneously by combining both reliability‐based and RD approaches into a single model with various customer aspirations. The application of the approach is demonstrated using a leaf spring design example. Copyright © 2009 John Wiley & Sons, Ltd.     

Design,preparation, and evaluation of liposomal gel formulations for treatment of acne: in vitro and in vivo studies

The study highlights the significance of co-application of bioactive components into liposomal gel formulations and their comparison to azithromycin for treatment of Acne. A Design of Experiments (DoE) approach was utilized to obtain optimized liposomal formulation encapsulating curcumin, with size and zeta potential of ～100?nm and ～14?mV, respectively, characterized by DLS, HR-TEM, FESEM, and AFM. The curcumin liposomal dispersion depicted excellent stability over the period of 60?days, which was further converted in gel form using Carbopol. Pharmacokinetics of curcumin-loaded liposomal gel showed that T_max for curcumin was achieved within 1?h of post application in both stratum corneum and skin, indicating quick penetration of nano-sized liposomes. Stratum corneum depicted C_max of 688.3?ng/mL and AUC_0-t of 5857.5?h?×?ng/mL, while the skin samples displayed C_max of 203.3?ng/gm and AUC_0-t of 2938.1?h?×?ng/gm. Lauric acid and azithromycin liposomal gel formulations were prepared as per the optimum parameters obtained by DoE. In antibacterial activity using agar diffusion assay, lauric acid gel formulation revealed ～1.5 fold improved antibacterial effect than curcumin gel formulation. Interestingly, their co-application (1:1) exhibited significantly enhanced antibacterial effect against both macrolide-sensitive (1.81 versus 1.25 folds) and resistant strains of P. acnes (2.93 versus 1.22 folds) than their individual counterparts. The in vivo studies in rat ear model displayed a ～2 fold reduction in comedones count and cytokines (TNF-α and IL-1β) on co-application with curcumin and lauric acid liposomal gel compared to placebo treated group.     

Propagation modes and regimes of intense laser beam in magnetized plasma

This paper presents an analytical and numerical investigation of a circularly polarized beam propagating along the static magnetic field parallel to oscillating magnetic field in plasma at relativistic intensities. In the high intensity regime, such a magnetic field is created by the pulse itself. The authors have identified three regimes of propagation taking into account the relativistic mass correction. Based on WKB and paraxial ray theory, an appropriate expression for a dielectric tensor has been evaluated in the presence of an externally applied magnetic field. The natural electromagnetic modes are circularly polarized. Consequently, extraordinary and ordinary modes propagate, which are significantly affected due to the relativistic mechanism. The regimes are characterized by dimensionless power and beamwidth, characterizing the nature of propagation as steady divergence, oscillatory divergence and self-focusing. Numerical computations are presented and discussed for typical parameters of laser plasma interaction; defined through critical parameters, namely cyclotron-to-beam frequency (Ω _c ), plasma-to-beam frequency (Ω _p ) and beam power for arbitrary large intensities.     

Dopant induced polarity inversion in polar ZnO nanorods

Highly oriented and polarity controlled ZnO nanorod thin films are deposited by chemical bath deposition where the preferred polarity depends on the anionic nature of the Zn salt. Significant differences are noticed in magnesium (Mg) doping concentration on Zn- and O-polar ZnO nanorods. Higher doping concentration is achieved in Zn polar nanorods, which is characterized with different spectroscopic techniques. A noteworthy contribution in morphological changes is noted upon by Mg doping on both Zn- and O-polar ZnO nanorods. Polarity inversion of the individual nanorods are found at certain doping condition, characterized by chemical etching rate measurements and Schottky Barrier Height determination of the individual nanorod.     

Error analysis of tomographic filters II: results

The convolution backprojection algorithm (CBP) has been studied from the point-of-view of the already published error formula which relates the error in reconstructions, under certain ideal conditions, to the Fourier-space derivatives of the filter functions employed in CBP. The results, for simulated images representing a damaged nuclear reactor fuel assembly and a cross-section of human brain, indicate that the error pattern obtained is in concurrence with the theory. Experimental results for a pixel size of 20 μm are also included.     

Ehrlichia chaffeensis and Rochalimaea antibodies in Kawasaki disease

Sera from 38 patients with Kawasaki disease were tested for immunofluorescent antibodies to Ehrlichia chaffeensis, Rochalimaea henselae, and R. quintana Oklahoma. Only 2.5% of the patients tested positive for E. chaffeensis, and 5% were positive for R. henselae and R. quintana Oklahoma. Our data suggest that Ehrlichia and Rochalimaea spp. do not play a unique role in the etiology of Kawasaki disease.     

Generalized Miller theorem and its applications

Four general Miller equivalent circuits, one for each of the four possible connections of two two-port networks, are derived. Based on these, a generalized Miller theorem is stated. A number of illustrative examples are included to demonstrate the power of the Miller theorem as an analytical tool in the analysis and synthesis of networks. It is pointed out that many known results such as capacitance multiplication, high input impedance of the emitter follower and the Darlington pair, and synthesis of driving point and transfer functions by some network configurations can be understood through the Miller theorem.<>