The lack of long-term detrimental effects on liver allografts caused by donor-specific anti-HLA antibodies

Recent reports indicate a higher incidence of both acute and chronic liver allograft rejection when, at the time of transplantation, the recipients serum contains donor-specific anti-HLA antibodies. From 9/89 to 5/91, 133 liver allografts were performed at our institution. Thirteen liver recipients had donor-specific IgG anti-HLA antibodies (complement-fixing) at the time of transplantation. In eleven patients, antibodies reacted to donor class I antigens while in 1 patient the donor-specific antibody had class II reactivity. Twelve patients have been followed for a minimum of 12 months (median 18 months, range 28-12 months). No hyperacute rejection was seen in any of the cases and four patients had acute rejections. Thus far only one of the twelve patients has biopsy evidence suggestive of chronic liver injury. The remaining have normal liver enzymes and bilirubin. Three of these twelve patients died (one from a myocardial infarction and the others from sepsis) accounting for a one-year graft survival of 75%. There was no significant statistical difference in the one-year graft survival in those recipients without donor-specific antibodies (i.e., 80.5%). In eight of the twelve patients, pretransplant preformed antibody level (PRA) was > 50%. In six of the thirteen patients donor-specific antibody was present at dilutions greater than 1:64. As previously reported, the donor-specific antibody disappeared from the serum posttransplant within hours and did not reappear. In vitro studies demonstrated no factor in portal or hepatic artery blood that could inhibit rabbit complement mediated lysis of anti-HLA antibodies. We conclude that it is not a contraindication to do liver transplants in the presence of donor-specific anti-HLA antibodies.     

锚网支护在综采工作面开切眼中的应用

介绍了平煤集团一矿在戊8— 310 40综合机械化采煤工作面开切眼实施煤巷锚网支护的基本情况。总结了经验 ,为同类条件下的锚网支护设计提供了依据。     

基于ODMG—93标准的面向对象视图集成机制

模式集成多数据库系统中需要解决的关键问题之一，己存在的大多数面向多数据库系统都采用了面向对象视图机制来建立集成模式。为了满足基于ＣＯＲＢＡ的ＣＩＭＳ信息集成平台呆订成的需要，本文提出了一种基于数据库管理组ＯＤＭＧ的ＯＤＭＧ－９３标准的视图集成机制并通过一个完整的例子说明了这种视图机制在模式集成中的应用。     

An anthropocentric approach to knowledge-based preventive maintenance

It is common knowledge today that application of sound manufacturing concepts and techniques will only provide cost-effective, long-term return when manufacturing functions are totally integrated with the operators, maintenance engineers and other associated personnel. This paper presents a human-centred methodology and its associated knowledge-based tool, to utilize equipment failure information for the purpose of machine down-time minimization. Based upon a structured and rigorous assessment of each breakdown, and combined with total employee participation, continuous improvement of maintenance function and operational effectiveness of equipment can be made a reality.     

核桃软糖的防粘结研究

主要针对核桃软糖在气温稍高、湿度较大的环境中容易粘结，造成质量下降和贮藏期缩短的现象，通过改进配方和工艺，防止和延缓核桃软糖粘结，延长了产品的贮藏时间。     

落脚河水电站引水发电系统的调节保证计算分析

水轮发电机组在运行中遇到启动、正常停机、增减负荷、事故甩负荷等工况变化时，经常会引起引水发电系统的水力过渡过程，所以在设计中必须通过调节保证计算以选择合适的导叶调节规律及其调节时间，从而优化压力引水系统的运行工况，使水电站的水工建筑物布置既经济合理又安全可靠。     

专用超大规模集成电路在LED显示系统中的应用

自1976年蒙特利尔奥运会采用了第一块黑白视频显示屏以来，各种大屏幕特别是LED显示屏得到了迅猛发展，在现代信息社会中更是随处可见。在这些显示系统中，应用了大量的不同种类的集成电路作为驱动芯片。本文叙述了运用于LED显示系统中的超大规模集成电路的强大功能。     

长安之星车用空调放大器的反求设计

长安之星空调放大器所具有延时启动、温度控制、过热保护、加速切断、点火控制以及转速控制等功能.该放大器以进口空调放大器为原型,通过其原理、结构及功能的分析,对软件和硬件分别进行反求设计,研制开发出能替代原产品的新产品.该产品硬件采用MDT2005单片机作核心控制,温度和水温采集用LM324实现模数转换,发动机转速经过两级滤波、降压后,再进入LM324作波形整理.MDT2005的8位计数器采用递增方式计数,当计至FFH时自动复零,并重新开始计数,一直循环.程序设计以循环方式与分支处理方式相结合,以实现空调放大器的各种控制功能与技术指标.     

n-Al2O3P/Ni复合刷镀层的组织和摩擦磨损特性

研究了镍基纳米Al2O3复合电刷镀层（n-Al2O3^p/Ni）的组织特征及擦磨损特性，并与快镍刷镀（Ni)进行了比较。结果表明：n-Al2O3^p/Ni复合刷镀层表面粗糙度更小，组织更致密，镀层摩擦系数随镀液中纳米粒子含量增加稍有增大；n-Al2O3在复合刷镀层中弥散分布，与基相良好结合；复合镀的耐磨性能明显优于Ni刷镀层，镀液中n-Al2O3含量为20g/L时，复合刷镀层具有最佳耐磨性能。