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The objectives of this study were 1) to evaluate interleukin-8 concentrations in cervical secretions in predicting preterm delivery, microbial invasion of the amniotic cavity and histologic chorioamnionitis in patients with preterm labor and intact membranes and 2) to compare the diagnostic value of interleukin-8 with fetal fibronectin determinations in predicting preterm delivery, microbial invasion of the amniotic cavity and histologic chorioamnionitis in patients with preterm labor and intact membranes. Interleukin-8 and fetal fibronectin were assayed in cervical secretions in 106 patients with singleton pregnancies and intact membranes admitted for preterm labor. Amniotic fluid obtained by amniocentesis was cultured and placentas (No = 43) analyzed for the presence of chorioamnionitis. The prevalence of pregnancies delivered preterm was 46.2% (49/106) and 15.09% (16/106) of amniotic fluid cultures were positive. Interleukin-8 levels in cervical secretions were significantly increased in patients who delivered preterm (p < or = 0.0001), in presence of positive amniotic fluid culture (p = 0.0016) and histological chorioamnionitis (p = 0.008) than in patients with negative findings. Receiver-operator characteristics curve analysis showed that an interleukin-8 value > 450 pg/ml is comparable to that of a fetal fibronectin value > 50 ng/ml in predicting preterm delivery (p = 0.247). Among patients who delivered preterm interleukin-8 concentrations > 860 pg/ml predicted a positive amniotic fluid culture with a sensitivity of 81.2% and a specificity 66.6%. Further, in patients who delivered preterm and had a negative amniotic fluid culture, IL-8 concentrations > 480 pg/ml predicted histological chorioamnionitis with a sensitivity 78.5% and specificity 61.5%. A positive fetal fibronectin > 50 ng/ml was not predictve of either a positive amniotic fluid culture or the presence of histological chorioamnionitis. In conclusion, increased concentrations of interleukin-8 and fetal fibronectin are associated with impending delivery and their diagnostic value seems comparable. However, interleukin-8 concentrations identify patients at risk of a positive amniotic fluid culture and the presence of histological chorioamnionitis. Measurement of interleukin-8 in cervical secretion is a non-invasive method to identify patients at risk for both preterm delivery and intrauterine infection.  相似文献   
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In this paper, characterization is given of clinical and biochemical features of VH B course against the background of narcomania. Recordable in such patient populations are high percentage of delta hepatitis (14.2%), unusual severity of the intoxication syndrome, protracted course with exacerbations (12.2%) and recurrences (8%), outcome being a chronic hepatitis (14.2%), slower normalization of biochemical indicators, persistently low ratio of AIAT activity in diluted and whole blood sera. The persistence of viral markers in drug addicts discharged from the hospital (68%) is fraught with danger of spreading viral hepatitis of prophylactic measures are not strictly observed.  相似文献   
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The fractal characteristics of an electromagnetic radiation signal image in a frequency range are calculated. It is shown that the fractal dimension of time section of the signal can serve as a characteristic that the failure surface has formed. __________ Translated from Fiziko-Tekhnicheskie Problemy Razrabotki Poleznykh Iskopaemykh, No. 2, pp. 55–68, March–April, 2007.  相似文献   
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The basic concepts of solid-state nuclear magnetic resonance (NMR) spectroscopy are explained in a clear and concise manner. First the reader is introduced to the principles of NMR spectroscopy and techniques that are most commonly utilized today. Next, an overview of advanced magic-angle spinning (MAS) NMR experiments, which can provide valuable insight into molecular structure, connectivity, dynamics, domains, and phases of inorganic polymers, is presented. The final chapter discusses the major classes of inorganic polymers, their properties and applications. It addresses their characterization including, if any, the role of solution and solid-state NMR spectroscopy, and provides prospective on potential applications of these techniques for the given class of material.  相似文献   
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Emulsifier‐free batch emulsion polymerization of n‐butyl acrylate and its semi‐batch copolymerization with 2,2,3,3,4,4,5,5‐octafluoropentyl acrylate and 2,2,3,4,4,4‐hexafluorobutyl acrylate both mediated by poly(acrylic acid) containing the trithiocarbonate group in the chain was employed to produce amphiphilic triblock copolymers. The polymerization‐induced self‐assembly of these copolymers in aqueous media gave rise to spherical core–shell particles. Irrespective of the experimental conditions, the polymeric product was characterized by a bimodal molecular weight distribution. The apparent violation of the reversible addition–fragmentation chain transfer polymerization mechanism may be attributed to restricted accessibility of the trithiocarbonate group in the self‐assembled block copolymers for propagating radicals that enter into the particle. Mean‐field theoretical arguments were employed to explain the exclusively spherical morphology of the particles observed in the experiment. © 2019 Society of Chemical Industry  相似文献   
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